Ken-Ichi Takemaru Selected Research

Catenins

3/2017	Chibby1 knockdown promotes mesenchymal-to-epithelial transition-like changes.
1/2015	14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia.
7/2014	Abrogation of β-catenin signaling in oligodendrocyte precursor cells reduces glial scarring and promotes axon regeneration after CNS injury.
9/2013	Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells.

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Ken-Ichi Takemaru Research Topics

Disease

6	Neoplasms (Cancer) 03/2017 - 02/2003
2	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2015 - 09/2013
1	Pancreatitis 01/2021
1	Pemphigus (Pemphigus Vulgaris) 01/2019
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2019
1	Ectopic Pregnancy 01/2017
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2017
1	Infections 01/2015
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 01/2015
1	Ciliopathies 10/2014
1	Cystic Kidney Diseases (Cystic Kidney Disease) 10/2014
1	Agenesis of Cerebellar Vermis 10/2014
1	Crush Injuries 07/2014
1	Cicatrix (Scar) 07/2014
1	Hypertrophy 07/2014
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 09/2013
1	Carcinoma (Carcinomatosis) 03/2006
1	Colorectal Neoplasms (Colorectal Cancer) 03/2006
1	Leukemia 01/2004
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2004
1	Autosomal Recessive 3 Severe Congenital Neutropenia 01/2004
1	Hamartoma 02/2003
1	Tuberous Sclerosis (Bourneville's Disease) 02/2003

Drug/Important Bio-Agent (IBA)

5	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2003
5	beta CateninIBA 06/2008 - 02/2003
4	CateninsIBA 03/2017 - 09/2013
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2015 - 09/2013
1	Egtazic Acid (EGTA)IBA 01/2019
1	GTP Phosphohydrolases (GTPases)IBA 01/2019
1	Immunoglobulin G (IgG)IBA 01/2019
1	DesmogleinsIBA 01/2019
1	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 01/2017
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2017
1	bcr-abl Fusion ProteinsIBA 09/2013
1	Glycogen Synthase Kinase 3IBA 09/2013
1	Messenger RNA (mRNA)IBA 03/2006
1	Peptide Hydrolases (Proteases)FDA Link 01/2004
1	Transcription Factors (Transcription Factor)IBA 01/2004
1	core binding factor alphaIBA 01/2004
1	Leukocyte Elastase (Neutrophil Elastase)IBA 01/2004
1	Oncogene Proteins (Oncogene Protein)IBA 04/2003
1	Tuberous Sclerosis Complex 2 ProteinIBA 02/2003
1	trans-sodium crocetinate (crocetin)IBA 02/2003
1	Cyclin D1IBA 02/2003

Therapy/Procedure

1	Transjugular Intrahepatic Portasystemic Shunt 01/2015