Hiroyuki Takano Selected Research

Wounds and Injuries (Trauma)

9/2014

Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice.

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Hiroyuki Takano Research Topics

Disease

17	Myocardial Infarction 02/2016 - 01/2003
14	Cardiomegaly (Heart Hypertrophy) 12/2011 - 01/2002
13	Heart Failure 02/2016 - 05/2003
11	Atherosclerosis 01/2017 - 01/2002
10	Cardiovascular Diseases (Cardiovascular Disease) 09/2017 - 01/2002
10	Ventricular Remodeling 08/2016 - 08/2003
6	Fibrosis (Cirrhosis) 12/2017 - 01/2002
6	Infarction (Infarctions) 08/2016 - 08/2003
5	Neoplasms (Cancer) 01/2022 - 02/2002
5	Myocardial Ischemia (Ischemic Heart Diseases) 02/2016 - 02/2006
4	Hypoxia (Hypoxemia) 09/2017 - 09/2014
4	Hypertrophy 01/2012 - 03/2002
3	Inflammation (Inflammations) 11/2021 - 08/2003
3	Myocarditis (Carditis) 05/2012 - 02/2005
3	Reperfusion Injury 06/2006 - 12/2003
2	Breast Neoplasms (Breast Cancer) 01/2022 - 02/2019
2	Lung Neoplasms (Lung Cancer) 01/2022 - 01/2022
2	Hypertension (High Blood Pressure) 01/2012 - 08/2008
2	Insulin Resistance 01/2010 - 01/2002
2	Acute Coronary Syndrome 09/2009 - 02/2004
2	Rheumatoid Arthritis 02/2009 - 01/2004
2	Diabetes Mellitus 02/2009 - 01/2004
2	Chronic Disease (Chronic Diseases) 02/2009 - 01/2004
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2009 - 01/2004
2	Alzheimer Disease (Alzheimer's Disease) 02/2009 - 01/2004
2	Ischemia 07/2006 - 06/2006
1	Compartment Syndromes 01/2020
1	Rhabdomyolysis 01/2020
1	Muscle Weakness 01/2020
1	Type 2 Diabetes Mellitus (MODY) 01/2017
1	Cicatrix (Scar) 08/2016
1	Heart Rupture 08/2016
1	Neoplasm Metastasis (Metastasis) 12/2014
1	Wounds and Injuries (Trauma) 09/2014
1	Death (Near-Death Experience) 01/2013
1	Essential Hypertension 11/2011
1	Kimura Disease 04/2010

Drug/Important Bio-Agent (IBA)

13	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 05/2012 - 01/2003
9	LigandsIBA 01/2010 - 01/2002
8	PPAR gammaIBA 01/2010 - 01/2002
5	CalcineurinIBA 12/2011 - 01/2002
4	Proteins (Proteins, Gene)FDA Link 01/2020 - 06/2002
4	Dipeptidyl-Peptidase IV InhibitorsIBA 12/2017 - 02/2016
4	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2013 - 08/2003
4	pitavastatin (itavastatin)FDA Link 01/2013 - 01/2012
4	CytokinesIBA 05/2004 - 01/2003
3	Transcription Factors (Transcription Factor)IBA 11/2021 - 06/2002
3	Phosphotransferases (Kinase)IBA 01/2020 - 07/2002
2	NucleotidesIBA 01/2022 - 06/2002
2	Glucose (Dextrose)FDA LinkGeneric 09/2017 - 04/2005
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2017 - 01/2002
2	Rosuvastatin Calcium (Crestor)FDA Link 01/2013 - 04/2012
2	Losartan (Cozaar)FDA LinkGeneric 01/2012 - 11/2011
2	Angiotensin Receptor AntagonistsIBA 01/2012 - 11/2011
2	Telmisartan (Micardis)FDA Link 01/2012 - 11/2011
2	Protein Kinases (Protein Kinase)IBA 12/2011 - 02/2002
2	Heat Shock Transcription FactorsIBA 11/2011 - 12/2003
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 11/2011 - 04/2005
2	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 06/2006 - 06/2004
2	Pioglitazone (Actos)FDA Link 02/2005 - 03/2002
2	Angiotensin IIIBA 06/2004 - 03/2002
2	Calmodulin (Calcium-Dependent Activator Protein)IBA 05/2003 - 07/2002
2	CalciumIBA 05/2003 - 07/2002
2	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 07/2002 - 02/2002
1	Cadherins (E-Cadherin)IBA 01/2022
1	Glutamine (L-Glutamine)FDA Link 01/2022
1	Inosine Monophosphate (IMP)IBA 01/2022
1	lometrexolIBA 01/2022
1	AngiomotinsIBA 01/2020
1	Propofol (Diprivan)FDA LinkGeneric 01/2020
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2020
1	TEA Domain Transcription FactorsIBA 01/2020
1	Forkhead Transcription Factors (Forkhead Box Proteins)IBA 02/2019
1	Estrogen ReceptorsIBA 02/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2019
1	CateninsIBA 09/2017
1	diprotin AIBA 09/2017
1	cadherin 5IBA 09/2017
1	CollagenIBA 08/2016
1	cyanoginosin LR (microcystin LR)IBA 12/2014
1	EnzymesIBA 09/2014
1	4-hydroxy-2-nonenal (4-hydroxynonenal)IBA 09/2014
1	Mitochondrial Aldehyde DehydrogenaseIBA 09/2014
1	AldehydesIBA 09/2014
1	TenascinIBA 05/2012
1	Apolipoproteins E (ApoE)IBA 05/2012
1	ApolipoproteinsIBA 05/2012
1	olmesartanIBA 01/2012
1	Valsartan (Vals)FDA Link 01/2012
1	candesartanIBA 01/2012
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 12/2011
1	Biomarkers (Surrogate Marker)IBA 11/2011
1	Erythropoietin FDA Link 06/2010
1	SteroidsIBA 04/2010

Therapy/Procedure

11	Therapeutics 04/2012 - 07/2002
1	Artificial Respiration (Mechanical Ventilation) 01/2020
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020
1	Fasciotomy 01/2020
1	Ligation 02/2016
1	Stents 09/2009