Xiaoyan Sun Selected Research

p21-Activated Kinases

6/2023	Azeliragon inhibits PAK1 and enhances the therapeutic efficacy of AKT inhibitors in pancreatic cancer.
4/2022	Natural Compound Shikonin Is a Novel PAK1 Inhibitor and Enhances Efficacy of Chemotherapy against Pancreatic Cancer Cells.
4/2020	Identification of a novel PAK1 inhibitor to treat pancreatic cancer.
10/2019	Targeting PKCι-PAK1 signaling pathways in EGFR and KRAS mutant adenocarcinoma and lung squamous cell carcinoma.

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Xiaoyan Sun Research Topics

Disease

53	Neoplasms (Cancer) 04/2024 - 09/2003
23	Alzheimer Disease (Alzheimer's Disease) 01/2024 - 12/2003
13	Inflammation (Inflammations) 12/2023 - 12/2012
11	Neoplasm Metastasis (Metastasis) 05/2023 - 01/2017
9	Wounds and Injuries (Trauma) 06/2021 - 03/2012
7	Adenocarcinoma of Lung 12/2023 - 05/2019
7	Pain (Aches) 01/2023 - 01/2013
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2022 - 01/2019
6	Chronic Obstructive Pulmonary Disease (COPD) 12/2023 - 01/2017
6	Melanoma (Melanoma, Malignant) 01/2023 - 08/2016
6	Hypoxia (Hypoxemia) 02/2017 - 01/2008
5	Sepsis (Septicemia) 09/2003 - 02/2002
4	Hemorrhage 12/2023 - 05/2019
4	Mitochondrial Diseases (Mitochondrial Disease) 11/2022 - 08/2015
4	Carcinogenesis 04/2020 - 03/2014
4	Cognitive Dysfunction 01/2018 - 08/2012
4	Insulin Resistance 04/2017 - 01/2014
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 10/2023 - 10/2018
3	Pancreatic Neoplasms (Pancreatic Cancer) 06/2023 - 04/2020
3	Lung Neoplasms (Lung Cancer) 10/2022 - 10/2019
3	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2022 - 01/2022
3	Reperfusion Injury 04/2010 - 01/2007
3	Heart Arrest (Cardiac Arrest) 04/2010 - 01/2007
2	Dementia (Dementias) 01/2024 - 08/2012
2	Bites and Stings (Sting) 01/2024 - 12/2023
2	Liver Neoplasms (Liver Cancer) 01/2024 - 01/2022
2	Keratitis 12/2023 - 01/2022
2	Atopic Dermatitis (Atopic Eczema) 09/2023 - 01/2022
2	Endometriosis 10/2022 - 05/2022
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2022 - 10/2019
2	Weight Loss (Weight Reduction) 01/2022 - 01/2017
2	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 07/2015
2	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 01/2022 - 04/2017
2	Colorectal Neoplasms (Colorectal Cancer) 04/2021 - 06/2017

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 01/2024 - 02/2002
13	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2009
7	Amyloid (Amyloid Fibrils)IBA 11/2022 - 12/2003
7	EnzymesIBA 01/2022 - 03/2005
7	Amyloid beta-PeptidesIBA 11/2009 - 12/2003
6	MicroRNAs (MicroRNA)IBA 10/2023 - 08/2016
6	Messenger RNA (mRNA)IBA 03/2022 - 02/2002
6	Peptides (Polypeptides)IBA 08/2015 - 12/2003
6	GlucocorticoidsIBA 02/2004 - 02/2002
5	CytokinesIBA 12/2023 - 12/2011
5	RNA (Ribonucleic Acid)IBA 11/2023 - 01/2018
5	AntioxidantsIBA 11/2022 - 01/2008
5	Transcription Factors (Transcription Factor)IBA 12/2021 - 02/2002
5	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 02/2004 - 02/2002
5	Mifepristone (RU 486)FDA Link 02/2004 - 02/2002
4	DNA (Deoxyribonucleic Acid)IBA 04/2024 - 02/2002
4	NeurograninIBA 01/2024 - 11/2016
4	Hormones (Hormone)IBA 11/2023 - 02/2002
4	p21-Activated KinasesIBA 06/2023 - 10/2019
4	Circular RNAIBA 10/2022 - 05/2020
4	salicylhydroxamic acid (SHAM)IBA 05/2022 - 02/2002
4	Glucose (Dextrose)FDA LinkGeneric 03/2022 - 01/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2017 - 08/2012
3	LipidsIBA 01/2024 - 08/2021
3	InflammasomesIBA 01/2024 - 12/2020
3	Phosphotransferases (Kinase)IBA 06/2023 - 01/2014
3	ErbB Receptors (EGF Receptor)IBA 09/2022 - 08/2016
3	EstersIBA 07/2022 - 01/2016
3	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 12/2020 - 01/2020
3	Immunologic Factors (Immunomodulators)IBA 08/2020 - 01/2018
3	Antidepressive Agents (Antidepressants)IBA 01/2020 - 12/2007
3	Retinaldehyde (Retinal)IBA 01/2018 - 01/2018
3	Insulin (Novolin)FDA Link 04/2017 - 01/2016
3	Angiopoietin-2IBA 02/2017 - 08/2012
3	Erythropoietin FDA Link 02/2017 - 08/2012
3	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 02/2017 - 08/2012
2	AntigensIBA 01/2024 - 01/2022
2	B7-H1 AntigenIBA 01/2024 - 07/2022
2	Interleukin-2 (IL2)IBA 01/2024 - 12/2011
2	Blood Glucose (Blood Sugar)IBA 11/2023 - 01/2017
2	PhosphoproteinsIBA 01/2023 - 01/2019
2	Immune Checkpoint InhibitorsIBA 09/2022 - 07/2022
2	Adenosine Triphosphate (ATP)IBA 09/2022 - 05/2022
2	IntegrinsIBA 09/2022 - 11/2019
2	AcidsIBA 07/2022 - 01/2022
2	Interleukin-6 (Interleukin 6)IBA 05/2022 - 01/2016
2	Indicators and Reagents (Reagents)IBA 01/2022 - 01/2016
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2022 - 01/2021
2	ImmunosorbentsIBA 01/2022 - 01/2022
2	Gemcitabine FDA Link 01/2022 - 04/2020
2	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 01/2022 - 01/2014
2	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 08/2021 - 01/2021
2	Anaplastic Lymphoma KinaseIBA 01/2021 - 01/2020
2	chikusetsu saponin IVaIBA 01/2021 - 01/2016

Therapy/Procedure

27	Therapeutics 04/2024 - 01/2014
10	Immunotherapy 01/2024 - 01/2018
5	Ligation 12/2023 - 02/2002
5	Punctures 10/2022 - 02/2002
4	Chinese Traditional Medicine (Traditional Chinese Medicine) 10/2022 - 12/2016
4	Drug Therapy (Chemotherapy) 09/2022 - 01/2018
3	Length of Stay 01/2023 - 01/2022
3	Resuscitation 04/2010 - 01/2007
2	Radiotherapy 04/2024 - 02/2012
2	Operative Time 12/2023 - 01/2021
2	Aftercare (After-Treatment) 05/2022 - 01/2021
2	Photothermal Therapy 05/2022 - 01/2020