Toshiro Sugiyama Selected Research

Inflammation (Inflammations)

6/2022	The potential of soluble CD14 in discriminating nonalcoholic steatohepatitis from nonalcoholic fatty liver disease.
1/2020	Transient Receptor Potential Vanilloid 4 Regulation of Adenosine Triphosphate Release by the Adenosine Triphosphate Transporter Vesicular Nucleotide Transporter, a Novel Therapeutic Target for Gastrointestinal Baroreception and Chronic Inflammation.
12/2019	Distinct DNA methylation targets by aging and chronic inflammation: a pilot study using gastric mucosa infected with Helicobacter pylori.
1/2015	Anti-inflammatory effect of cinnamaldehyde in Helicobacter pylori induced gastric inflammation.
12/2013	IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.
1/2013	A case of primary biliary cirrhosis that progressed rapidly after treatment involving rituximab.
1/2012	Theaflavin attenuates ischemia-reperfusion injury in a mouse fatty liver model.
9/2005	Geranylgeranylacetone protects mice from dextran sulfate sodium-induced colitis.
2/2005	Pathophysiological roles of macrophage migration inhibitory factor in gastrointestinal, hepatic, and pancreatic disorders.

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Toshiro Sugiyama Research Topics

Disease

22	Neoplasms (Cancer) 08/2018 - 02/2003
22	Autistic Disorder (Autism) 03/2017 - 12/2006
17	Infections 10/2023 - 01/2002
14	Stomach Neoplasms (Stomach Cancer) 10/2018 - 07/2007
9	Inflammation (Inflammations) 06/2022 - 02/2005
9	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 08/2005
8	Peptic Ulcer (Peptic Ulcers) 01/2018 - 01/2003
8	Neoplasm Metastasis (Metastasis) 01/2017 - 04/2008
7	Autism Spectrum Disorder 08/2020 - 01/2010
6	Hemorrhage 06/2018 - 11/2010
6	Ulcer 07/2015 - 01/2003
5	Liver Cirrhosis (Hepatic Cirrhosis) 07/2018 - 06/2008
5	Stomach Ulcer (Gastric Ulcer) 07/2015 - 02/2004
5	Carcinogenesis 02/2015 - 09/2004
4	Non-alcoholic Fatty Liver Disease 06/2022 - 06/2009
4	Fibrosis (Cirrhosis) 06/2022 - 12/2013
4	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 09/2021 - 06/2004
4	Gastroesophageal Reflux (GERD) 01/2018 - 07/2011
4	Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor) 04/2016 - 06/2008
4	Fatty Liver 02/2016 - 08/2009
4	Carcinoma (Carcinomatosis) 04/2011 - 01/2002
4	Duodenal Ulcer (Curling's Ulcer) 11/2010 - 02/2004
4	Colitis 07/2007 - 07/2002
3	Hypersensitivity (Allergy) 01/2021 - 07/2011
3	Lymphoma (Lymphomas) 04/2018 - 06/2004
3	Reperfusion Injury 01/2017 - 01/2012
3	Hepatitis B 07/2016 - 07/2010
3	Colorectal Neoplasms (Colorectal Cancer) 12/2013 - 04/2011
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2012 - 07/2002
2	Pain (Aches) 01/2021 - 12/2010
2	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020 - 01/2009
2	Esophageal Neoplasms (Esophageal Cancer) 08/2018 - 09/2015
2	Neuroendocrine Carcinoma 03/2018 - 01/2015
2	Hepatic Encephalopathy 01/2018 - 02/2011
2	Wounds and Injuries (Trauma) 01/2018 - 04/2015
2	Hypoxia (Hypoxemia) 01/2017 - 02/2003
2	Liver Diseases (Liver Disease) 09/2016 - 01/2013
2	Dyspepsia (Indigestion) 01/2015 - 02/2013
2	Pancreatitis 01/2015 - 02/2012
2	Pancreatic Neoplasms (Pancreatic Cancer) 01/2013 - 02/2003

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 04/2017 - 10/2004
8	CytokinesIBA 07/2018 - 07/2002
8	Messenger RNA (mRNA)IBA 04/2017 - 07/2002
7	DNA (Deoxyribonucleic Acid)IBA 09/2015 - 05/2005
5	AcidsIBA 01/2021 - 07/2011
5	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2018 - 04/2008
5	Proton Pump InhibitorsIBA 01/2018 - 03/2004
5	Imatinib Mesylate (Gleevec)FDA Link 04/2016 - 06/2008
5	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 07/2015 - 02/2004
4	Docetaxel (Taxotere)FDA Link 10/2018 - 04/2010
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 03/2017 - 09/2005
4	Monoclonal AntibodiesIBA 12/2013 - 03/2004
4	AntibodiesIBA 10/2011 - 07/2002
4	Serotonin (5 Hydroxytryptamine)IBA 03/2011 - 10/2008
4	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2010 - 02/2005
3	UreaseIBA 01/2023 - 03/2004
3	S-1 plus cisplatinIBA 10/2018 - 01/2012
3	Rituximab (Mabthera)FDA Link 04/2018 - 01/2013
3	Methionine (L-Methionine)FDA Link 02/2016 - 08/2005
3	Choline (Choline Chloride)IBA 02/2016 - 05/2010
3	Cisplatin (Platino)FDA LinkGeneric 02/2016 - 01/2011
3	Fluorouracil (Carac)FDA LinkGeneric 02/2016 - 02/2009
3	Oxytocin Receptors (Oxytocin Receptor)IBA 01/2016 - 03/2010
3	Sorafenib (BAY 43-9006)FDA Link 07/2015 - 04/2010
3	Anti-Bacterial Agents (Antibiotics)IBA 05/2015 - 03/2004
3	Irinotecan (Camptosar)FDA LinkGeneric 11/2013 - 01/2011
3	EnzymesIBA 02/2012 - 01/2007
3	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 03/2011 - 10/2008
3	Glutamic Acid (Glutamate)FDA Link 09/2007 - 12/2006
3	Dextran SulfateIBA 07/2007 - 07/2002
3	CarcinogensIBA 09/2004 - 01/2002
2	nasIBA 06/2022 - 06/2009
2	InterferonsIBA 09/2021 - 12/2013
2	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2021 - 04/2007
2	NucleotidesIBA 01/2020 - 09/2015
2	MicroRNAs (MicroRNA)IBA 12/2019 - 05/2009
2	ParaffinIBA 08/2018 - 09/2015
2	Formaldehyde (Formol)FDA Link 08/2018 - 09/2015
2	Biomarkers (Surrogate Marker)IBA 08/2018 - 11/2012
2	Paclitaxel (Taxol)FDA LinkGeneric 03/2018 - 10/2012
2	AmmoniaIBA 01/2018 - 02/2011
2	Branched-Chain Amino AcidsIBA 01/2018 - 02/2011
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 09/2016 - 07/2012
2	Antiviral Agents (Antivirals)IBA 05/2016 - 12/2010
2	Serine (L-Serine)FDA Link 04/2016 - 12/2006
2	IronIBA 02/2016 - 04/2009
2	Infliximab (Remicade)FDA Link 10/2015 - 09/2011
2	PlatinumIBA 01/2015 - 11/2013
2	acceleratory factor from growth hormone (AcG)IBA 09/2014 - 11/2012
2	Immunoglobulin M (IgM)IBA 01/2014 - 10/2011
2	Collagen Type I (Type I Collagen)IBA 12/2013 - 08/2009
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 11/2013 - 01/2012
2	Immunoglobulins (Immunoglobulin)IBA 08/2013 - 04/2007

Therapy/Procedure

20	Therapeutics 10/2023 - 01/2003
19	Drug Therapy (Chemotherapy) 03/2018 - 07/2007
4	Aftercare (After-Treatment) 01/2013 - 01/2003
3	Oral Administration 04/2015 - 09/2005
2	Combination Drug Therapy (Combination Chemotherapy) 03/2018 - 02/2011
2	Liver Transplantation 09/2017 - 12/2010
2	Radiofrequency Ablation 07/2016 - 02/2009