Hiroyuki Sugimoto Selected Research

acarboxyprothrombin (PIVKA)

10/2009	The tumor suppressor NPRL2 in hepatocellular carcinoma plays an important role in progression and can be served as an independent prognostic factor.
2/2003	Des-gamma-carboxy prothrombin (DCP) ratio, a novel parameter measured by monoclonal antibodies MU-3 and 19B7, as a new prognostic indicator for hepatocellular carcinoma.

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Hiroyuki Sugimoto Research Topics

Disease

65	Neoplasms (Cancer) 01/2020 - 02/2003
34	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 02/2003
25	Stomach Neoplasms (Stomach Cancer) 01/2018 - 09/2012
16	Neoplasm Metastasis (Metastasis) 01/2019 - 06/2005
16	Pancreatic Neoplasms (Pancreatic Cancer) 03/2017 - 04/2008
11	Fibrosis (Cirrhosis) 03/2022 - 05/2002
8	Pancreatic Fistula (Pancreatic Fistulas) 02/2016 - 01/2006
7	Adenocarcinoma 07/2016 - 03/2010
6	Melanoma (Melanoma, Malignant) 01/2017 - 12/2013
6	Colorectal Neoplasms (Colorectal Cancer) 01/2017 - 10/2012
6	Lymphatic Metastasis 09/2016 - 01/2009
5	Carcinogenesis 05/2015 - 04/2003
4	Starvation 01/2022 - 04/2010
4	Disease Progression 12/2015 - 10/2004
4	Inflammation (Inflammations) 12/2015 - 10/2008
4	Infections 05/2015 - 01/2011
4	Head and Neck Neoplasms (Head and Neck Cancer) 05/2012 - 06/2005
3	Heart Failure 11/2021 - 01/2018
3	Liver Diseases (Liver Disease) 01/2018 - 04/2005
3	Esophageal Neoplasms (Esophageal Cancer) 05/2015 - 11/2012
2	Pituitary Neoplasms (Pituitary Adenoma) 03/2024 - 01/2020
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2019 - 12/2014
2	Breast Neoplasms (Breast Cancer) 11/2017 - 04/2015
2	Sarcopenia 03/2017 - 06/2016
2	Esophageal Squamous Cell Carcinoma 01/2017 - 02/2016
2	Body Weight (Weight, Body) 03/2016 - 01/2006
2	Thrombosis (Thrombus) 01/2016 - 10/2004
2	Hemorrhage 01/2016 - 11/2015
2	Pathologic Constriction (Stenosis) 04/2015 - 04/2012
2	Pleural Effusion (Pleural Effusions) 03/2015 - 12/2009
2	Lymphoma (Lymphomas) 10/2010 - 10/2004
2	Hypersensitivity (Allergy) 10/2008 - 10/2008
1	Acute Kidney Injury (Acute Renal Failure) 01/2022
1	Atrial Fibrillation 01/2022
1	Glioblastoma (Glioblastoma Multiforme) 01/2022
1	Renal Insufficiency (Renal Failure) 01/2022
1	Obesity 01/2022
1	Insulin Resistance 11/2021
1	Type 2 Diabetes Mellitus (MODY) 11/2021

Drug/Important Bio-Agent (IBA)

25	Messenger RNA (mRNA)IBA 01/2022 - 01/2014
16	Biomarkers (Surrogate Marker)IBA 01/2018 - 02/2014
9	Proteins (Proteins, Gene)FDA Link 11/2016 - 04/2010
7	AntigensIBA 08/2016 - 04/2007
5	Bevacizumab (Avastin)FDA Link 01/2017 - 09/2012
5	Cadherins (E-Cadherin)IBA 11/2014 - 07/2007
4	BilirubinIBA 01/2019 - 09/2002
4	Indicators and Reagents (Reagents)IBA 03/2015 - 02/2003
4	Contrast MediaIBA 10/2012 - 11/2002
3	Protein Isoforms (Isoforms)IBA 01/2020 - 11/2014
3	AlbuminsIBA 01/2019 - 11/2011
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2019 - 05/2002
3	CarbohydratesIBA 01/2018 - 09/2014
3	VimentinIBA 11/2014 - 11/2013
2	Carboplatin (JM8)FDA LinkGeneric 05/2019 - 12/2014
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2018 - 07/2010
2	Carcinoembryonic AntigenIBA 01/2018 - 09/2014
2	Blood Coagulation Factors (Coagulation Factor)IBA 02/2017 - 11/2014
2	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 02/2017 - 09/2016
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2017 - 04/2014
2	Phosphatidylcholines (Phosphatidylcholine)IBA 11/2016 - 06/2011
2	Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA 08/2016 - 03/2016
2	Transcription Factors (Transcription Factor)IBA 03/2016 - 11/2014
2	Cell Adhesion MoleculesIBA 02/2016 - 08/2014
2	Vitamin K FDA Link 12/2015 - 05/2015
2	Tumor Biomarkers (Tumor Markers)IBA 12/2015 - 01/2015
2	Sorafenib (BAY 43-9006)FDA Link 10/2015 - 11/2014
2	dihydropyrimidinaseIBA 05/2015 - 08/2014
2	Monoclonal AntibodiesIBA 04/2015 - 02/2003
2	Gemcitabine FDA Link 11/2013 - 04/2008
2	Epidermal Growth Factor (EGF)IBA 01/2013 - 03/2010
2	fibulinIBA 08/2011 - 03/2010
2	acarboxyprothrombin (PIVKA)IBA 10/2009 - 02/2003
2	Thymic Stromal LymphopoietinIBA 10/2008 - 10/2008
1	Hormones (Hormone)IBA 03/2024
1	Cholesterol 24-Hydroxylase (CYP46A1)IBA 01/2022
1	Thyroid HormonesIBA 01/2022
1	CreatinineIBA 01/2022
1	Co-Repressor ProteinsIBA 01/2022
1	Blood Glucose (Blood Sugar)IBA 11/2021
1	dapagliflozinIBA 11/2021

Therapy/Procedure

22	Therapeutics 03/2022 - 01/2007
15	Pancreatectomy 02/2016 - 08/2009
13	Hepatectomy 09/2017 - 09/2002
12	Gastrectomy 01/2018 - 01/2016
10	Pancreaticoduodenectomy 11/2015 - 08/2009
8	Lymph Node Excision (Lymph Node Dissection) 07/2017 - 06/2005
8	Drug Therapy (Chemotherapy) 03/2017 - 04/2008
5	Adjuvant Chemotherapy 03/2017 - 11/2013
5	Esophagectomy 05/2015 - 11/2012
3	Laparotomy 05/2017 - 01/2008
3	Blood Transfusion (Blood Transfusions) 07/2016 - 05/2009
3	Neoadjuvant Therapy 09/2015 - 08/2011
2	Perioperative Period 01/2022 - 09/2016
2	Liver Transplantation 09/2016 - 07/2010
2	Enteral Nutrition (Feeding, Tube) 11/2015 - 05/2015
2	Aftercare (After-Treatment) 07/2015 - 12/2009
2	Injections 09/2012 - 01/2011
2	Oncolytic Virotherapy 09/2011 - 04/2008
2	Contraindications 05/2009 - 01/2009
1	Catheter Ablation 01/2022