Nicole Streiner Selected Research

PF-06840003

12/2018

Characterization of the Selective Indoleamine 2,3-Dioxygenase-1 (IDO1) Catalytic Inhibitor EOS200271/PF-06840003 Supports IDO1 as a Critical Resistance Mechanism to PD-(L)1 Blockade Therapy.

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Nicole Streiner Research Topics

Disease

10	Neoplasms (Cancer) 12/2021 - 12/2010
2	Hypoxia (Hypoxemia) 04/2012 - 12/2010
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 09/2012
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/2012
1	Ovarian Neoplasms (Ovarian Cancer) 04/2012
1	Prostatic Neoplasms (Prostate Cancer) 10/2011
1	Pain (Aches) 03/2011

Drug/Important Bio-Agent (IBA)

5	silmitasertibIBA 09/2012 - 12/2010
3	Casein Kinase II (Casein Kinase 2)IBA 09/2012 - 01/2011
2	ErbB Receptors (EGF Receptor)IBA 09/2012 - 04/2012
2	proto-oncogene proteins pimIBA 05/2012 - 02/2012
2	Carboxylic AcidsIBA 10/2011 - 01/2011
1	Biomarkers (Surrogate Marker)IBA 12/2021
1	KynurenineIBA 12/2018
1	PF-06840003IBA 12/2018
1	LigandsIBA 12/2018
1	Blocking AntibodiesIBA 12/2018
1	Tyrosine Kinase InhibitorsIBA 09/2012
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 09/2012
1	Drug CombinationsIBA 04/2012
1	Interleukin-6 (Interleukin 6)IBA 04/2012
1	Cisplatin (Platino)FDA LinkGeneric 04/2012
1	Gemcitabine FDA Link 04/2012
1	Proteins (Proteins, Gene)FDA Link 10/2011
1	Formaldehyde (Formol)FDA Link 03/2011
1	Ribosomal RNAIBA 02/2011
1	DNA-Directed RNA Polymerases (RNA Polymerase)IBA 02/2011
1	RNA Polymerase I (Polymerase I, RNA)IBA 02/2011
1	CX 5461IBA 02/2011
1	Adenosine Triphosphate (ATP)IBA 01/2011

Therapy/Procedure

4	Therapeutics 12/2018 - 03/2011
1	Immunotherapy 12/2018