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Monica Spinola Selected Research

Lung Neoplasms (Lung Cancer)

12/2010Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.
3/2010MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment.
3/2010Genome-wide association study in discordant sibships identifies multiple inherited susceptibility alleles linked to lung cancer.
3/2009Transcription deregulation at the 15q25 locus in association with lung adenocarcinoma risk.
10/2007New molecularly targeted therapies for lung cancer.
9/2007Evidence of gene gene interactions in lung carcinogenesis in a large pooled analysis.
6/2007Genome-wide single nucleotide polymorphism analysis of lung cancer risk detects the KLF6 gene.
3/2007Ethnic differences in frequencies of gene polymorphisms in the MYCL1 region and modulation of lung cancer patients' survival.
4/2006Association of the PDCD5 locus with lung cancer risk and prognosis in smokers.
12/2005Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study.
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Monica Spinola Research Topics

Disease

11Lung Neoplasms (Lung Cancer)
12/2010 - 02/2005
10Neoplasms (Cancer)
12/2010 - 04/2003
7Asthma (Bronchial Asthma)
11/2019 - 12/2011
6Adenocarcinoma of Lung
12/2010 - 02/2005
4Genetic Predisposition to Disease (Genetic Predisposition)
09/2007 - 04/2003
2Chronic Obstructive Pulmonary Disease (COPD)
01/2017 - 01/2016
2Adenocarcinoma
02/2010 - 03/2009
2Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2004 - 04/2003
1Inflammation (Inflammations)
12/2011
1Hyperplasia
02/2010
1Carcinoma in Situ
02/2010
1Adenoma (Adenomas)
02/2005
1Carcinogenesis
11/2003
1Skin Neoplasms (Skin Cancer)
04/2003

Drug/Important Bio-Agent (IBA)

7Beclomethasone (Beclometasone)FDA Link
01/2017 - 12/2011
7Formoterol Fumarate (Oxis)FDA Link
01/2017 - 12/2011
7DNA (Deoxyribonucleic Acid)IBA
03/2010 - 02/2005
5Adrenal Cortex Hormones (Corticosteroids)IBA
01/2017 - 03/2012
5Messenger RNA (mRNA)IBA
03/2010 - 08/2005
5Proteins (Proteins, Gene)FDA Link
02/2010 - 04/2003
2Cytochrome P-450 CYP1A1 (CYP1A1)IBA
09/2007 - 12/2005
2Environmental CarcinogensIBA
09/2007 - 12/2005
2CarcinogensIBA
09/2007 - 12/2005
2tRNA isopentenyltransferaseIBA
03/2007 - 08/2005
2Complementary DNA (cDNA)IBA
04/2006 - 11/2003
1Glycopyrrolate (Glycopyrronium Bromide)FDA LinkGeneric
01/2017
1Tiotropium Bromide (Spiriva)FDA Link
01/2017
1Muscarinic AntagonistsIBA
01/2017
1Fluticasone-Salmeterol Drug Combination (Advair)FDA Link
10/2016
1AerosolsIBA
03/2012
1SteroidsIBA
12/2011
1Adenosine Monophosphate (AMP)IBA
12/2011
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2011
1Aldehyde DehydrogenaseIBA
12/2010
1Small Interfering RNA (siRNA)IBA
12/2010
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
12/2010
1Type 4 Fibroblast Growth Factor ReceptorIBA
06/2009
1Proteasome Endopeptidase Complex (Proteasome)IBA
03/2009
1Cholinergic ReceptorsIBA
03/2009
1Iron Regulatory Protein 2IBA
03/2009
1Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA
09/2007
1SmokeIBA
09/2007
1IsopentenyladenosineIBA
06/2007
1phenylalanylphenylalanineIBA
03/2007
1ElementsIBA
03/2007
1arginylarginine (Arg-Arg)IBA
10/2005
1Transfer RNA (tRNA)IBA
08/2005
1RNA IsoformsIBA
08/2005
1Amino AcidsFDA Link
02/2005
1EnzymesIBA
05/2004
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
05/2004
1Monophenol Monooxygenase (Tyrosinase)IBA
05/2004
1SerpinsIBA
04/2003

Therapy/Procedure

3Therapeutics
11/2019 - 10/2007
3Nebulizers and Vaporizers (Inhaler)
10/2014 - 12/2011
2Dry Powder Inhalers
10/2014 - 09/2014
1Precision Medicine
11/2019
1Drug Therapy (Chemotherapy)
03/2012