John J Spinelli Selected Research

Prednisone (Sone)

1/2017	Genetic polymorphism at BCL2 as a predictor for rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone efficacy in patients with diffuse large B-cell lymphoma.
8/2005	Introduction of combined CHOP plus rituximab therapy dramatically improved outcome of diffuse large B-cell lymphoma in British Columbia.

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John J Spinelli Research Topics

Disease

34	Neoplasms (Cancer) 05/2023 - 08/2003
20	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2005
16	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/2020 - 08/2005
8	Multiple Myeloma 05/2023 - 03/2006
6	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 12/2020 - 08/2005
4	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 12/2020 - 09/2005
4	Lymphoma (Lymphomas) 01/2020 - 09/2005
3	Colorectal Neoplasms (Colorectal Cancer) 01/2023 - 01/2022
3	Hodgkin Disease (Hodgkin's Disease) 06/2020 - 03/2006
3	Hypersensitivity (Allergy) 01/2020 - 12/2012
3	Leukemia 08/2014 - 03/2008
2	Cutaneous Malignant Melanoma 01/2022 - 04/2011
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 12/2020 - 04/2016
2	Inflammation (Inflammations) 10/2019 - 11/2018
2	Autoimmune Diseases (Autoimmune Disease) 10/2019 - 08/2014
2	Insulin Resistance 11/2018 - 03/2014
2	Seasonal Allergic Rhinitis (Hay Fever) 08/2014 - 12/2012
2	Herpes Zoster 01/2012 - 08/2003
2	Prostatic Neoplasms (Prostate Cancer) 01/2008 - 10/2007
1	Carcinogenesis 05/2023
1	Type 2 Diabetes Mellitus (MODY) 01/2021
1	Uterine Cervical Dysplasia 01/2021
1	Infections 10/2020
1	Hematologic Neoplasms (Hematological Malignancy) 10/2020
1	Genetic Risk Score 01/2020
1	T-Cell Lymphoma (Lymphoma, T Cell) 01/2020
1	Disease Progression 01/2020
1	Chromosome Fragility 01/2019
1	Triple Negative Breast Neoplasms 01/2019
1	Bone Fractures (Bone Fracture) 04/2018
1	Alzheimer Disease (Alzheimer's Disease) 03/2017
1	Necrosis 01/2017
1	Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral) 04/2016
1	Urinary Bladder Neoplasms (Bladder Cancer) 12/2015
1	Eczema 08/2014

Drug/Important Bio-Agent (IBA)

9	Estrogen ReceptorsIBA 01/2022 - 01/2014
6	Biomarkers (Surrogate Marker)IBA 05/2023 - 09/2005
6	Progesterone Receptors (Progesterone Receptor)IBA 01/2022 - 01/2014
6	PesticidesIBA 06/2020 - 02/2009
4	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2022 - 04/2007
4	InsecticidesIBA 12/2020 - 01/2012
4	ORALIT (ORS)IBA 01/2020 - 05/2008
3	Proteins (Proteins, Gene)FDA Link 05/2023 - 05/2014
3	human ERBB2 proteinIBA 01/2022 - 01/2019
3	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 11/2007
3	Hormones (Hormone)IBA 01/2021 - 01/2019
3	Polychlorinated Biphenyls (PCBs)IBA 10/2018 - 12/2007
3	Rituximab (Mabthera)FDA Link 01/2017 - 08/2005
3	Insulin-Like PeptidesIBA 01/2016 - 01/2008
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2023 - 06/2022
2	Angiotensin Receptor AntagonistsIBA 01/2023 - 06/2022
2	Antihypertensive Agents (Antihypertensives)IBA 01/2023 - 06/2022
2	DiureticsIBA 01/2023 - 06/2022
2	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 01/2023 - 06/2022
2	Progesterone FDA LinkGeneric 01/2021 - 01/2014
2	Tamoxifen FDA LinkGeneric 01/2020 - 04/2018
2	Transcription Factors (Transcription Factor)IBA 01/2020 - 11/2017
2	AntigensIBA 10/2019 - 05/2014
2	OrganophosphatesIBA 01/2019 - 12/2012
2	HLA Antigens (Human Leukocyte Antigens)IBA 01/2018 - 10/2014
2	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017 - 08/2005
2	CytokinesIBA 01/2017 - 01/2006
2	Vincristine (Oncovin)FDA LinkGeneric 01/2017 - 08/2005
2	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2017 - 08/2005
2	Prednisone (Sone)FDA LinkGeneric 01/2017 - 08/2005
2	Antidepressive Agents (Antidepressants)IBA 05/2014 - 05/2013
2	Interleukin-10 (Interleukin 10)IBA 02/2010 - 01/2006
2	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2010 - 10/2009
2	Insect RepellentsIBA 03/2006 - 08/2005
1	Immunoglobulins (Immunoglobulin)IBA 05/2023
1	Persistent Organic PollutantsIBA 01/2022
1	XenobioticsIBA 01/2022
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2022
1	Papillomavirus Vaccines (HPV Vaccines)IBA 01/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	Homeodomain Proteins (Proteins, Homeobox)IBA 01/2020
1	Phenobarbital (Luminal)FDA Link 01/2020
1	Glyphosate (Roundup)IBA 11/2019
1	CarbamatesIBA 01/2019
1	diepoxybutaneIBA 01/2019
1	olaparibIBA 01/2019
1	A-Form DNA (A-DNA)IBA 01/2019
1	lysyllysine (Lys-Lys)IBA 01/2019
1	Branched-Chain Amino AcidsIBA 11/2018
1	Glycoproteins (Glycoprotein)IBA 11/2018
1	FatsIBA 11/2018
1	A-factor (Streptomyces)IBA 11/2018
1	Aromatase InhibitorsIBA 04/2018
1	Apolipoproteins E (ApoE)IBA 03/2017
1	CholesterolIBA 03/2017
1	LipidsIBA 03/2017
1	Vitamin D FDA LinkGeneric 05/2016
1	cyclo(Arg-Pro) (CI 4)IBA 12/2015
1	HLA-A Antigens (HLA-A)IBA 05/2014

Therapy/Procedure

3	Therapeutics 01/2022 - 08/2005
2	Blood Transfusion (Blood Transfusions) 08/2019 - 08/2014
2	Length of Stay 04/2003 - 07/2002
1	Tattooing 10/2020
1	Tonsillectomy 01/2020