Dominik Spensberger Selected Research

Neoplasms (Cancer)

1/2023	PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.
1/2018	Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
11/2017	PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.
9/2010	JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia.

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Dominik Spensberger Research Topics

Disease

4	Neoplasms (Cancer) 01/2023 - 09/2010
2	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 11/2017
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/2008 - 06/2005
1	Cytopenia 05/2024
1	Infections 01/2023
1	Breast Neoplasms (Breast Cancer) 11/2017
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 06/2011
1	Leukemia 06/2011
1	Essential Thrombocythemia 09/2010
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 08/2008
1	Chromosome Aberrations (Chromosome Abnormalities) 08/2008

Drug/Important Bio-Agent (IBA)

2	phosphoinositide-3,4-bisphosphateIBA 01/2023 - 11/2017
2	Transcription Factors (Transcription Factor)IBA 06/2011 - 08/2008
1	plastinIBA 05/2024
1	Messenger RNA (mRNA)IBA 01/2023
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 01/2023
1	Immunoglobulins (Immunoglobulin)IBA 01/2023
1	Tyrosine (L-Tyrosine)FDA Link 01/2023
1	Epidermal Growth Factor (EGF)IBA 11/2017
1	phosphoinositide-3,4,5-triphosphateIBA 11/2017
1	Hemoglobins (Hemoglobin)IBA 09/2010
1	Histone MethyltransferasesIBA 08/2008
1	Proteins (Proteins, Gene)FDA Link 06/2005

Therapy/Procedure

1	Immunotherapy 01/2018
1	Transplantation 09/2010