Manuela Sommerfeld Selected Research

Telmisartan (Micardis)

1/2017	AT1-receptor blockade attenuates outward aortic remodeling associated with diet-induced obesity in mice.
12/2008	Telmisartan prevents aneurysm progression in the rat by inhibiting proteolysis, apoptosis and inflammation.

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Manuela Sommerfeld Research Topics

Disease

3	Fibrosis (Cirrhosis) 05/2021 - 07/2013
3	Myocardial Infarction 05/2021 - 12/2008
3	Infarction (Infarctions) 05/2021 - 12/2008
3	Aneurysm (Aneurysms) 01/2018 - 09/2004
2	Abdominal Aortic Aneurysm 01/2018 - 12/2008
2	Obesity 01/2018 - 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 12/2022
1	Neoplasms (Cancer) 05/2021
1	Metabolic Diseases (Metabolic Disease) 12/2020
1	Glucose Intolerance 01/2018
1	Insulin Resistance 01/2018
1	Hypertension (High Blood Pressure) 01/2016
1	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2016
1	Chronic Renal Insufficiency 01/2016
1	Hypertrophy 01/2016
1	Weight Gain 07/2013
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 07/2013
1	Necrosis 12/2008
1	Inflammation (Inflammations) 12/2008
1	Atherosclerotic Plaque (Atheroma) 09/2004
1	Atherosclerosis 09/2004
1	Aortic Aneurysm (Aneurysm, Aortic) 09/2004
1	Vascular Remodeling 09/2004
1	Fatty Liver 09/2004
1	Genetic Predisposition to Disease (Genetic Predisposition) 09/2004

Drug/Important Bio-Agent (IBA)

3	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2021 - 03/2014
3	Type 2 Angiotensin ReceptorIBA 01/2018 - 12/2008
3	compound 21IBA 01/2018 - 12/2008
2	Proteins (Proteins, Gene)FDA Link 05/2021 - 12/2008
2	salicylhydroxamic acid (SHAM)IBA 01/2018 - 12/2008
2	Pancreatic Elastase (Elastase)IBA 01/2018 - 12/2008
2	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2017 - 01/2016
2	Telmisartan (Micardis)FDA Link 01/2017 - 12/2008
2	CollagenIBA 03/2014 - 07/2013
2	Caspase 3 (Caspase-3)IBA 12/2008 - 12/2008
2	Fas Ligand Protein (Fas Ligand)IBA 12/2008 - 12/2008
1	CannabinoidsIBA 12/2022
1	empagliflozinIBA 05/2021
1	Matrix Metalloproteinases (MMPs)IBA 05/2021
1	Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA 05/2021
1	Sodium-Hydrogen Exchanger 1IBA 05/2021
1	Proline (L-Proline)FDA Link 12/2020
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	ElastinIBA 01/2016
1	Angiotensin IIIBA 01/2016
1	Valsartan (Vals)FDA Link 01/2016
1	Transforming Growth Factors (Transforming Growth Factor)IBA 03/2014
1	Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA 03/2014
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 07/2013
1	RimonabantIBA 07/2013
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 07/2013
1	NF-kappa B (NF-kB)IBA 12/2008
1	Metalloproteases (Metalloproteinases)IBA 12/2008
1	Angiotensin II Type 1 Receptor BlockersIBA 12/2008
1	Cathepsin DIBA 12/2008
1	CholesterolIBA 09/2004
1	LipidsIBA 09/2004
1	Kininogens (Kininogen)IBA 09/2004

Therapy/Procedure

2	Ligation 05/2021 - 12/2008
1	Catheters 12/2008