Nikaïa Smith Selected Research

COVID-19

5/2024	Increased levels of GM-CSF and CXCL10 and low CD8+ memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people.
11/2022	Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.
11/2021	Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.
1/2021	Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection.
10/2020	Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.
1/2020	Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.

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Nikaïa Smith Research Topics

Disease

10	Infections 01/2023 - 01/2013
6	COVID-19 05/2024 - 01/2020
4	Inflammation (Inflammations) 01/2023 - 01/2019
3	HIV Infections (HIV Infection) 01/2016 - 01/2013
2	Pneumonia (Pneumonitis) 11/2022 - 10/2020
2	Neoplasms (Cancer) 01/2019 - 01/2017
1	Arthritis (Polyarthritis) 01/2023
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 01/2023
1	Bone Resorption 01/2023
1	Disease Progression 01/2023
1	Tuberculosis (Tuberculoses) 01/2022
1	Latent Infection 11/2021
1	COVID-19 related pediatric multisystem inflammatory disease 10/2021
1	Myocarditis (Carditis) 10/2021
1	Melanoma (Melanoma, Malignant) 01/2021
1	Severe Dengue 01/2020
1	Glomerulonephritis 01/2019
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019
1	Virus Diseases (Viral Diseases) 07/2018
1	Bites and Stings (Sting) 01/2017
1	Human Influenza (Influenza) 01/2017
1	Carcinogenesis 01/2017

Drug/Important Bio-Agent (IBA)

8	Interferon Type IIBA 11/2022 - 01/2017
6	CytokinesIBA 05/2024 - 01/2019
3	InterferonsIBA 11/2022 - 07/2018
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2021 - 01/2016
3	Antiviral Agents (Antivirals)IBA 01/2021 - 01/2013
2	Histamine (Histamine Dihydrochloride)FDA Link 01/2023 - 01/2017
2	LigandsIBA 01/2019 - 01/2013
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2024
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 05/2024
1	SpermineIBA 01/2023
1	CollagenIBA 01/2023
1	SpermidineIBA 01/2023
1	Chemokine ReceptorsIBA 01/2023
1	AutoantibodiesIBA 11/2022
1	Proteins (Proteins, Gene)FDA Link 11/2022
1	Interleukin-1 (Interleukin 1)IBA 01/2022
1	SolutionsIBA 11/2021
1	AntibodiesIBA 11/2021
1	Neutralizing AntibodiesIBA 11/2021
1	ChemokinesIBA 10/2021
1	Immune Checkpoint InhibitorsIBA 01/2021
1	Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA 10/2020
1	Toll-Like Receptor 3IBA 10/2020
1	Interleukin-6 (Interleukin 6)IBA 01/2020
1	anti-dsDNA autoantibodyIBA 01/2019
1	Toll-Like Receptor 7IBA 01/2019
1	DNA (Deoxyribonucleic Acid)IBA 01/2017
1	B-Cell Activating FactorIBA 01/2016

Therapy/Procedure

1	Therapeutics 01/2017