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Tomasz Skorski Selected Research

Dacarbazine (DIC)

1/2023Histone Deacetylases (HDAC) Inhibitor-Valproic Acid Sensitizes Human Melanoma Cells to Dacarbazine and PARP Inhibitor.
11/2016PARP1 inhibitor olaparib (Lynparza) exerts synthetic lethal effect against ligase 4-deficient melanomas.

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Tomasz Skorski Research Topics

Disease

43Leukemia
11/2023 - 01/2002
30Neoplasms (Cancer)
04/2024 - 05/2002
28BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021 - 08/2002
12Genomic Instability
01/2024 - 05/2002
5Chromosome Aberrations (Chromosome Abnormalities)
05/2013 - 09/2008
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
05/2024 - 01/2018
4Genetic Translocation (Chromosomal Translocation)
04/2008 - 06/2002
3Philadelphia Chromosome
10/2005 - 08/2002
3Lymphoma (Lymphomas)
06/2002 - 01/2002
2Hematologic Neoplasms (Hematological Malignancy)
12/2023 - 01/2023
2Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
12/2023 - 04/2008
2Glioblastoma (Glioblastoma Multiforme)
08/2023 - 12/2018
2Melanoma (Melanoma, Malignant)
01/2023 - 11/2016
2Breast Neoplasms (Breast Cancer)
06/2020 - 10/2018
2Prostatic Neoplasms (Prostate Cancer)
01/2019 - 05/2005
2Disease Progression
01/2018 - 07/2011
2Glioma (Gliomas)
07/2017 - 11/2016
2Carcinoma (Carcinomatosis)
01/2016 - 08/2013
2Myeloproliferative Disorders (Myeloproliferative Disorder)
06/2012 - 09/2008
2Blast Crisis (Blast Phase)
07/2011 - 09/2008
2Lymphoid Leukemia
10/2005 - 08/2002
2Myeloid Leukemia (Leukemia, Myelocytic)
11/2004 - 11/2002
2Non-Hodgkin Lymphoma (Lymphosarcoma)
03/2003 - 06/2002
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
12/2023
1Ovarian Neoplasms (Ovarian Cancer)
04/2023
1Hypoxia (Hypoxemia)
10/2020
1Carcinogenesis
01/2019
1Burkitt Lymphoma (Burkitt's Lymphoma)
01/2017
1Hypersensitivity (Allergy)
01/2017

Drug/Important Bio-Agent (IBA)

21Phosphotransferases (Kinase)IBA
11/2023 - 05/2002
21DNA (Deoxyribonucleic Acid)IBA
11/2023 - 05/2002
17Imatinib Mesylate (Gleevec)FDA Link
01/2021 - 08/2002
13Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
10/2019 - 01/2002
12Proteins (Proteins, Gene)FDA Link
04/2024 - 04/2004
101,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
04/2023 - 06/2002
9Poly(ADP-ribose) Polymerase InhibitorsIBA
11/2023 - 12/2017
8Reactive Oxygen Species (Oxygen Radicals)IBA
01/2018 - 05/2007
7Tyrosine Kinase InhibitorsIBA
01/2021 - 02/2011
6Tyrosine (L-Tyrosine)FDA Link
11/2023 - 05/2002
5talazoparibIBA
08/2023 - 01/2017
4Serine (L-Serine)FDA Link
11/2023 - 05/2006
4Therapeutic UsesIBA
11/2023 - 01/2017
4Alkylating AgentsIBA
08/2023 - 11/2016
4Histones (Histone)IBA
08/2023 - 05/2006
4olaparibIBA
06/2020 - 11/2016
4bcr-abl Fusion ProteinsIBA
05/2007 - 12/2004
4Anaplastic Lymphoma KinaseIBA
12/2004 - 01/2002
3Histone Deacetylases (Histone Deacetylase)IBA
08/2023 - 02/2012
3Peptides (Polypeptides)IBA
08/2013 - 07/2011
3Cisplatin (Platino)FDA LinkGeneric
05/2006 - 05/2005
2DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
04/2024 - 11/2023
2Doxorubicin (Adriamycin)FDA LinkGeneric
10/2023 - 01/2006
2Valproic Acid (Depakote)FDA LinkGeneric
08/2023 - 01/2023
2Temozolomide (Temodar)FDA LinkGeneric
08/2023 - 12/2018
2Histone Deacetylase InhibitorsIBA
08/2023 - 01/2023
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2023 - 06/2017
2Dacarbazine (DIC)FDA LinkGeneric
01/2023 - 11/2016
2Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
10/2019 - 07/2007
2NAD (NADH)IBA
01/2019 - 01/2019
2DNA Ligases (Ligases, DNA)IBA
12/2018 - 11/2016
2BRCA1 ProteinIBA
10/2018 - 01/2014
2AntioxidantsIBA
01/2018 - 07/2006
2EnzymesIBA
01/2018 - 11/2016
2Mitomycin (Mitomycin-C)FDA LinkGeneric
02/2012 - 05/2006
2Oncogene Proteins (Oncogene Protein)IBA
07/2010 - 11/2004
2Complementary DNA (cDNA)IBA
04/2006 - 06/2003
1Biomarkers (Surrogate Marker)IBA
05/2024
1NucleosidesIBA
12/2023
1ProdrugsIBA
12/2023
1Formaldehyde (Formol)FDA Link
11/2023
1CCCTC-Binding FactorIBA
10/2023
1DNA Polymerase thetaIBA
10/2023
1ProteomeIBA
04/2023
1Transcription Factors (Transcription Factor)IBA
04/2023
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
04/2023
1nuclear pore complex protein 98IBA
01/2023
1Novobiocin (Streptonivicin)FDA Link
12/2022
1Interleukin-21 ReceptorsIBA
01/2022
1Type II Tumor Necrosis Factor ReceptorsIBA
01/2022
1DioxygenasesIBA
10/2021
1Staphylococcal Protein A (Protein A)IBA
01/2021
1NucleotidesIBA
01/2021
1Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
01/2021
1Transforming Growth Factor beta (TGF-beta)IBA
10/2020
1Transforming Growth Factor beta Receptors (TGF beta Receptors)IBA
10/2020
1poly ADP-ribose glycohydrolaseIBA
01/2019
1RNA-Binding Proteins (RNA-Binding Protein)IBA
10/2018
1Protein Kinase CIBA
01/2018
1Protein Kinase C-epsilonIBA
01/2018
1fms-Like Tyrosine Kinase 3IBA
01/2018
1ruxolitinibIBA
12/2017
1Messenger RNA (mRNA)IBA
07/2017
1DNA-Activated Protein KinaseIBA
06/2017
1Cytarabine (Cytosar-U)FDA LinkGeneric
01/2017
1Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA
01/2017

Therapy/Procedure

16Therapeutics
10/2023 - 04/2008
4Drug Therapy (Chemotherapy)
10/2023 - 01/2017
4Precision Medicine
11/2022 - 11/2015
2Aftercare (After-Treatment)
11/2016 - 05/2006
1Radiotherapy
12/2018