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Adam Skarka Selected Research

Tyrosine Kinase Inhibitors

11/2021Tepotinib Inhibits Several Drug Efflux Transporters and Biotransformation Enzymes: The Role in Drug-Drug Interactions and Targeting Cytostatic Resistance In Vitro and Ex Vivo.
3/2020Ensartinib (X-396) Effectively Modulates Pharmacokinetic Resistance Mediated by ABCB1 and ABCG2 Drug Efflux Transporters and CYP3A4 Biotransformation Enzyme.

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Adam Skarka Research Topics

Disease

14Neoplasms (Cancer)
10/2023 - 10/2009
3Intestinal Neoplasms (Intestinal Cancer)
11/2017 - 08/2015
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2021 - 03/2020
2Breast Neoplasms (Breast Cancer)
11/2017 - 08/2015
1Hypoxia (Hypoxemia)
04/2024
1Glioma (Gliomas)
04/2024
1Alzheimer Disease (Alzheimer's Disease)
10/2023
1Carcinoma (Carcinomatosis)
10/2022
1Colonic Neoplasms (Colon Cancer)
10/2022
1Colorectal Neoplasms (Colorectal Cancer)
12/2021
1Organophosphate Poisoning
12/2018

Drug/Important Bio-Agent (IBA)

6Doxorubicin (Adriamycin)FDA LinkGeneric
01/2019 - 08/2015
3EnzymesIBA
10/2023 - 09/2014
3caryophyllene oxideIBA
11/2017 - 08/2015
3nerolidolIBA
11/2017 - 08/2015
3SesquiterpenesIBA
11/2017 - 08/2015
3Volatile Oils (Essential Oils)IBA
06/2017 - 08/2015
3AnthracyclinesIBA
09/2014 - 05/2011
2Hormones (Hormone)IBA
10/2023 - 09/2014
2Oxidoreductases (Dehydrogenase)IBA
10/2023 - 08/2015
2Cadherins (E-Cadherin)IBA
10/2022 - 12/2021
2Tyrosine Kinase InhibitorsIBA
11/2021 - 03/2020
2valenceneIBA
06/2017 - 08/2015
2humuleneIBA
06/2017 - 08/2015
2Cytostatic AgentsIBA
06/2017 - 01/2016
1Formaldehyde (Formol)FDA Link
04/2024
1ParaffinIBA
04/2024
1MLN 8237IBA
01/2022
1Aurora Kinase AIBA
01/2022
1Sirolimus (Rapamycin)FDA Link
01/2022
1Oxaliplatin (Eloxatin)FDA LinkGeneric
12/2021
1Irinotecan (Camptosar)FDA LinkGeneric
12/2021
1tepotinibIBA
11/2021
1Messenger RNA (mRNA)IBA
03/2020
1ensartinibIBA
03/2020
1AnthelminticsIBA
01/2019
1flubendazoleIBA
01/2019
1benzimidazoleIBA
01/2019
1TubulinIBA
01/2019
1AcidsIBA
12/2018
1AntidotesIBA
12/2018
1Nerve AgentsIBA
12/2018
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2016
1AntioxidantsIBA
01/2016
1caryophylleneIBA
08/2015
1Docetaxel (Taxotere)FDA Link
08/2015
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
08/2015
1Fluorouracil (Carac)FDA LinkGeneric
08/2015
1Paclitaxel (Taxol)FDA LinkGeneric
08/2015
1TamoxifenFDA LinkGeneric
08/2015
1Idarubicin (4 Demethoxydaunorubicin)FDA LinkGeneric
08/2014
1Daunorubicin (Cerubidine)FDA LinkGeneric
08/2014
1Aldo-Keto ReductasesIBA
08/2014
12'-hydroxyflavanoneIBA
08/2014
1oracineIBA
10/2009

Therapy/Procedure

4Therapeutics
01/2022 - 08/2015
2Drug Therapy (Chemotherapy)
08/2015 - 08/2014