Kamaleshwar P Singh Selected Research

Carcinogenesis

1/2024	Estrogen-induced reactive oxygen species, through epigenetic reprogramming, causes increased growth in breast cancer cells.
7/2020	Pressurized liquid extraction followed by liquid chromatography coupled to a fluorescence detector and atmospheric pressure chemical ionization mass spectrometry for the determination of benzo(a)pyrene metabolites in liver tissue of an animal model of colon cancer.
1/2019	Arsenic-Induced Neoplastic Transformation Involves Epithelial-Mesenchymal Transition and Activation of the β-Catenin/c-Myc Pathway in Human Kidney Epithelial Cells.
1/2014	Chronic oxidative stress increases growth and tumorigenic potential of MCF-7 breast cancer cells.
1/2012	Effects of chronic exposure to arsenic and estrogen on epigenetic regulatory genes expression and epigenetic code in human prostate epithelial cells.
3/2011	Chronic exposure to arsenic causes increased cell survival, DNA damage, and increased expression of mitochondrial transcription factor A (mtTFA) in human prostate epithelial cells.
6/2009	Long duration exposure to cadmium leads to increased cell survival, decreased DNA repair capacity, and genomic instability in mouse testicular Leydig cells.
1/2008	Allelic loss and mutations in a new ETRG-1 gene are early events in diethylstilbestrol-induced renal carcinogenesis in Syrian hamsters.
7/2007	Gene expression changes and induction of cell proliferation by chronic exposure to arsenic of mouse testicular Leydig cells.
1/2007	Genetic and epigenetic changes induced by chronic low dose exposure to arsenic of mouse testicular Leydig cells.

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Kamaleshwar P Singh Research Topics

Disease

15	Neoplasms (Cancer) 01/2023 - 01/2004
12	Carcinogenesis 01/2024 - 01/2004
10	Breast Neoplasms (Breast Cancer) 01/2024 - 07/2005
5	Kidney Neoplasms (Kidney Cancer) 11/2022 - 01/2016
3	Fibrosis (Cirrhosis) 12/2023 - 01/2019
3	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 01/2012
3	Renal Cell Carcinoma (Grawitz Tumor) 11/2022 - 01/2016
2	Visceral Leishmaniasis (Kala Azar) 11/2023 - 01/2021
2	Infections 11/2023 - 01/2021
2	Genomic Instability 06/2009 - 01/2007
1	Neglected Diseases 11/2023
1	Leishmaniasis 11/2023
1	Cutaneous Leishmaniasis 11/2023
1	Bites and Stings (Sting) 01/2021
1	Colonic Neoplasms (Colon Cancer) 07/2020
1	Kidney Diseases (Kidney Disease) 11/2018
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 02/2015
1	Lung Neoplasms (Lung Cancer) 01/2012
1	Testicular Neoplasms (Testicular Cancer) 07/2007

Drug/Important Bio-Agent (IBA)

9	Estrogens (Estrogen)FDA Link 01/2024 - 05/2005
8	ArsenicIBA 12/2023 - 01/2007
6	Doxorubicin (Adriamycin)FDA LinkGeneric 06/2021 - 01/2012
4	Diethylstilbestrol (Stilbestrol)FDA Link 01/2024 - 01/2004
4	DNA (Deoxyribonucleic Acid)IBA 02/2015 - 03/2004
3	Estradiol (Delestrogen)FDA LinkGeneric 01/2024 - 03/2012
3	Estradiol Congeners (Synthetic Estrogens)IBA 01/2024 - 01/2008
3	AntioxidantsIBA 01/2024 - 05/2005
3	CarcinogensIBA 07/2020 - 01/2008
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024 - 01/2014
2	VaccinesIBA 11/2023 - 01/2021
2	Nicotine FDA Link 01/2019 - 11/2018
2	Estrogen ReceptorsIBA 06/2017 - 08/2015
2	Oxidants (Oxidizing Agents)IBA 07/2005 - 05/2005
1	Cysteine (L-Cysteine)FDA Link 01/2024
1	AntigensIBA 11/2023
1	leishmaninIBA 11/2023
1	AndrogensIBA 01/2023
1	Androgen Receptors (Androgen Receptor)IBA 01/2023
1	Folic Acid (Vitamin M)FDA LinkGeneric 11/2022
1	theasinensin AIBA 06/2021
1	Interleukin-10 (Interleukin 10)IBA 01/2021
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 01/2021
1	Leishmaniasis VaccinesIBA 01/2021
1	Benzo(a)pyreneIBA 07/2020
1	CollagenIBA 01/2019
1	Fibronectins (Fibronectin)IBA 01/2019
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2019
1	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2019
1	CateninsIBA 01/2019
1	Cisplatin (Platino)FDA LinkGeneric 01/2017
1	Estrogen Receptor alphaIBA 08/2015
1	PolyphenolsIBA 02/2015
1	TeaIBA 02/2015
1	Decitabine FDA Link 02/2015
1	leptomycin BIBA 01/2012
1	CadmiumIBA 06/2009
1	Biomarkers (Surrogate Marker)IBA 01/2008
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 05/2005
1	Nuclear Respiratory Factor 1IBA 05/2005
1	Transcription Factors (Transcription Factor)IBA 05/2005
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 03/2004
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 01/2004

Therapy/Procedure

10	Therapeutics 01/2023 - 07/2005
8	Drug Therapy (Chemotherapy) 01/2023 - 01/2016
1	Immunotherapy 01/2023
1	Intradermal Injections 01/2021