Thomas T Simopoulos Selected Research

Intervertebral Disc Displacement (Herniated Disc)

10/2022	Comparative Systematic Review and Meta-Analysis of Cochrane Review of Epidural Injections for Lumbar Radiculopathy or Sciatica.
1/2021	Epidural Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Comprehensive Evidence-Based Guidelines.
1/2015	Comparison of the efficacy of saline, local anesthetics, and steroids in epidural and facet joint injections for the management of spinal pain: A systematic review of randomized controlled trials.
4/2013	An update of comprehensive evidence-based guidelines for interventional techniques in chronic spinal pain. Part II: guidance and recommendations.
4/2010	Plasma disc decompression compared with fluoroscopy-guided transforaminal epidural steroid injections for symptomatic contained lumbar disc herniation: a prospective, randomized, controlled trial.

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Thomas T Simopoulos Research Topics

Disease

30	Pain (Aches) 12/2023 - 07/2003
10	Chronic Pain 10/2023 - 09/2005
8	Neuralgia (Stump Neuralgia) 11/2023 - 01/2013
5	Intervertebral Disc Displacement (Herniated Disc) 10/2022 - 04/2010
5	Intractable Pain 04/2022 - 03/2008
4	Spinal Stenosis (Stenosis, Spinal) 10/2022 - 09/2008
3	Radiculopathy (Radiculopathy, Cervical) 10/2022 - 04/2010
3	Infections 10/2021 - 09/2008
3	Low Back Pain (Lumbago) 11/2012 - 01/2005
2	Wounds and Injuries (Trauma) 11/2023 - 07/2014
2	Post-Dural Puncture Headache 11/2023 - 10/2016
2	Post-Traumatic Headache 02/2023 - 11/2022
2	Neck Pain (Cervicalgia) 02/2023 - 11/2022
2	COVID-19 01/2022 - 01/2020
2	Hemorrhage 01/2019 - 04/2013
2	Hematoma 01/2019 - 04/2013
2	Opioid-Related Disorders (Opiate Addiction) 01/2017 - 07/2014
2	Cancer Pain 01/2017 - 09/2009
2	Back Pain (Backache) 04/2010 - 09/2008
1	Respiratory Insufficiency (Respiratory Failure) 10/2023
1	Postoperative Pain 03/2023
1	Sciatica (Sciatic Neuralgia) 10/2022
1	Paresthesia (Dysesthesia) 02/2021
1	Pathologic Constriction (Stenosis) 01/2021
1	Brain Injuries (Brain Injury) 01/2019
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 01/2019
1	Hypoventilation 01/2019
1	Spinal Cord Injuries (Spinal Cord Injury) 01/2019
1	Ankylosing Spondylitis 01/2019
1	Thrombosis (Thrombus) 01/2019
1	Complex Regional Pain Syndromes 01/2019
1	Substance-Related Disorders (Drug Abuse) 01/2017
1	Constipation 01/2017
1	Headache (Headaches) 10/2016
1	Failed Back Surgery Syndrome 04/2013
1	Hypersensitivity (Allergy) 01/2013
1	Dermatitis 01/2013
1	Shoulder Pain 01/2012

Drug/Important Bio-Agent (IBA)

6	SteroidsIBA 10/2022 - 09/2008
4	Local AnestheticsIBA 01/2015 - 01/2005
3	Opioid Analgesics (Opioids)IBA 03/2023 - 07/2014
2	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020 - 01/2012
2	Ticlopidine (Ticlid)FDA LinkGeneric 01/2019 - 04/2013
2	Prasugrel Hydrochloride FDA Link 01/2019 - 04/2013
2	AnticoagulantsIBA 01/2019 - 04/2013
2	Warfarin (Coumadin)FDA LinkGeneric 01/2019 - 04/2013
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2019 - 04/2013
2	Phosphodiesterase InhibitorsIBA 01/2019 - 04/2013
2	Dabigatran FDA Link 01/2019 - 04/2013
2	Cilostazol (Pletal)FDA LinkGeneric 01/2019 - 04/2013
2	Clopidogrel (Plavix)FDA Link 01/2019 - 04/2013
2	Dipyridamole (Persantine)FDA LinkGeneric 01/2019 - 04/2013
2	RivaroxabanIBA 01/2019 - 04/2013
2	Analgesics (Analgesic Drugs)IBA 07/2016 - 01/2012
1	Gabapentin (Neurontin)FDA LinkGeneric 10/2023
1	Anti-Bacterial Agents (Antibiotics)IBA 10/2021
1	Heparin (Liquaemin)FDA LinkGeneric 01/2019
1	desirudin (Iprivask)FDA Link 01/2019
1	bivalirudin (Angiomax)FDA Link 01/2019
1	lepirudin (Refludan)FDA Link 01/2019
1	apixabanIBA 01/2019
1	betrixabanIBA 01/2019
1	edoxabanIBA 01/2019
1	Fondaparinux (Arixtra)FDA Link 01/2019
1	TicagrelorIBA 01/2019
1	Dihydrotachysterol (AT 10)IBA 01/2019
1	argatroban (MPQA)FDA Link 01/2019
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2019
1	HirudinsIBA 01/2019
1	Controlled SubstancesIBA 01/2017
1	Botulinum Toxins (Botulinum Toxin)IBA 09/2015
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 04/2013
1	Fibrinolytic Agents (Antithrombotic Agents)IBA 04/2013
1	Dipyridamole Drug Combination Aspirin FDA LinkGeneric 04/2013
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 04/2013
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2013
1	Anesthetics (Anesthetic Agents)IBA 01/2012

Therapy/Procedure

17	Spinal Cord Stimulation 12/2023 - 05/2010
15	Therapeutics 12/2023 - 03/2008
8	Injections 10/2022 - 09/2008
5	Denervation 02/2023 - 05/2012
4	Pain Management 12/2023 - 07/2011
4	Epidural Injections 10/2022 - 09/2008
4	Nerve Block (Nerve Blocks) 01/2022 - 11/2012
3	Intra-Articular Injections 01/2022 - 01/2012
2	Punctures 11/2023 - 10/2016
2	Conduction Anesthesia (Regional Anesthesia) 12/2021 - 10/2021
2	Conservative Treatment 01/2021 - 10/2016
1	Arthrodesis 01/2022
1	Bridge Therapy 01/2019
1	Conscious Sedation 01/2019
1	Surgical Decompression 01/2019
1	Perioperative Period 01/2019
1	Transjugular Intrahepatic Portasystemic Shunt 01/2017
1	Epidural Blood Patch 10/2016
1	Activities of Daily Living (ADL) 07/2016
1	Radiofrequency Ablation 07/2011
1	Knee Replacement Arthroplasty (Total Knee Replacement) 05/2010
1	Decompression 04/2010
1	Combined Modality Therapy 09/2009