Naoki Shinojima Selected Research

Vorinostat

1/2020

Histone deacetylase inhibition enhances the therapeutic effects of methotrexate on primary central nervous system lymphoma.

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Naoki Shinojima Research Topics

Disease

26	Neoplasms (Cancer) 03/2024 - 05/2002
13	Glioma (Gliomas) 01/2023 - 05/2003
7	Glioblastoma (Glioblastoma Multiforme) 07/2023 - 10/2003
6	Lymphoma (Lymphomas) 01/2024 - 01/2018
3	Craniopharyngioma (Craniopharyngiomas) 01/2024 - 01/2015
3	Carcinogenesis 01/2023 - 05/2009
3	Pituitary Neoplasms (Pituitary Adenoma) 09/2019 - 09/2017
3	Astrocytoma (Pilocytic Astrocytoma) 04/2016 - 10/2003
2	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2009
2	Germinoma 01/2021 - 01/2021
2	Leukemia 05/2009 - 03/2009
1	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 07/2023
1	Chordoma 07/2023
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 02/2023
1	Gliosarcoma 01/2022
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2021
1	Diabetes Insipidus 01/2021
1	Burkitt Lymphoma (Burkitt's Lymphoma) 01/2020
1	Type 2 Diabetes Mellitus (MODY) 09/2019
1	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 05/2019
1	Hyperthyroidism 11/2018
1	Papillary Thyroid Cancer 11/2018
1	Thyroid Crisis (Thyrotoxic Crisis) 11/2018
1	Growth Hormone-Secreting Pituitary Adenoma 09/2017
1	Dystonia (Limb Dystonia) 03/2016
1	Parkinson Disease (Parkinson's Disease) 01/2016
1	Camptocormia 01/2016
1	Meningioma (Meningiomas) 09/2015
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2011
1	Pathologic Processes 09/2010
1	Wounds and Injuries (Trauma) 09/2010
1	Stroke (Strokes) 09/2010

Drug/Important Bio-Agent (IBA)

3	Agammaglobulinaemia Tyrosine KinaseIBA 01/2024 - 01/2021
3	tirabrutinibIBA 01/2024 - 01/2021
3	Methotrexate (Mexate)FDA LinkGeneric 01/2023 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2020 - 01/2018
2	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 07/2023 - 01/2023
2	MethyltransferasesIBA 01/2023 - 02/2004
2	Temozolomide (Temodar)FDA LinkGeneric 01/2023 - 05/2014
2	NF-kappa B (NF-kB)IBA 01/2022 - 11/2007
2	Tumor Biomarkers (Tumor Markers)IBA 01/2021 - 01/2021
2	Growth Hormone (Somatotropin)IBA 09/2019 - 09/2017
2	Conditioned Culture MediaIBA 01/2018 - 01/2010
2	AcidsIBA 01/2014 - 02/2004
2	Tyrosine (L-Tyrosine)FDA Link 10/2011 - 05/2009
2	Imatinib Mesylate (Gleevec)FDA Link 05/2009 - 03/2009
2	DNA (Deoxyribonucleic Acid)IBA 02/2004 - 05/2002
1	Brachyury protein (Brachyury)IBA 01/2024
1	Immune Checkpoint InhibitorsIBA 07/2023
1	Biomarkers (Surrogate Marker)IBA 07/2023
1	Macrophage Colony-Stimulating FactorIBA 02/2023
1	Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA 02/2023
1	alpha-hydroxyglutarateIBA 01/2023
1	Ribosomal Proteins (Ribosomal Protein)IBA 04/2022
1	Etoposide (VP 16)FDA LinkGeneric 01/2022
1	Interleukin-6 (Interleukin 6)IBA 01/2022
1	Ifosfamide FDA LinkGeneric 01/2022
1	Carboplatin (JM8)FDA LinkGeneric 01/2022
1	InterleukinsIBA 01/2022
1	Ribosomal Protein S6IBA 06/2020
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2020
1	Leucovorin (Folinic Acid)FDA Link 01/2020
1	Histone Deacetylase InhibitorsIBA 01/2020
1	folylpolyglutamate synthetaseIBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	HydrolasesIBA 01/2020
1	Vorinostat FDA Link 01/2020
1	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)IBA 01/2020
1	Transfer RNA (tRNA)IBA 09/2019
1	EnzymesIBA 09/2019
1	Hormones (Hormone)IBA 09/2019
1	Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA 05/2019
1	indium-111-octreotideIBA 11/2018
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 11/2018
1	Octreotide (Sandostatin)FDA LinkGeneric 11/2018
1	Small Interfering RNA (siRNA)IBA 01/2018
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2018
1	Ligases (Synthetase)IBA 01/2018
1	Histones (Histone)IBA 04/2016
1	Levodopa (L Dopa)FDA LinkGeneric 01/2016
1	Neurofibromin 2 (Merlin)IBA 09/2015
1	Fibrin Tissue Adhesive (Fibrin Sealant)IBA 05/2014
1	Caspase 3 (Caspase-3)IBA 05/2014
1	AntibodiesIBA 05/2014
1	Polyglactin 910IBA 01/2014
1	Prostaglandins AIBA 01/2014
1	Retinoblastoma ProteinIBA 10/2010

Therapy/Procedure

13	Therapeutics 01/2022 - 05/2003
8	Radiotherapy 03/2024 - 02/2004
4	Drug Therapy (Chemotherapy) 03/2024 - 02/2004
2	Deep Brain Stimulation 03/2016 - 01/2016
1	Immunotherapy 07/2023
1	Salvage Therapy 01/2022
1	Craniospinal Irradiation 01/2021
1	Ligation 05/2019
1	Perioperative Period 11/2018
1	Operative Surgical Procedures 04/2017
1	Endoscopes 01/2015
1	Surgical Instruments (Clip) 01/2015
1	Intra-Arterial Injections 08/2011