Nobuyuki Shimizu Selected Research

Burns

3/2013	iNOS inhibitor, L-NIL, reverses burn-induced glycogen synthase kinase-3β activation in skeletal muscle of rats.
1/2012	Inducible nitric oxide synthase deficiency ameliorates skeletal muscle insulin resistance but does not alter unexpected lower blood glucose levels after burn injury in C57BL/6 mice.

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Nobuyuki Shimizu Research Topics

Disease

15	Stomach Neoplasms (Stomach Cancer) 09/2018 - 04/2002
12	Inflammation (Inflammations) 01/2024 - 03/2004
9	Neoplasms (Cancer) 07/2018 - 02/2005
6	Infections 07/2023 - 01/2002
5	Insulin Resistance 01/2012 - 04/2005
4	Hyperglycemia 10/2011 - 05/2005
4	Carcinogenesis 07/2009 - 10/2002
3	Thrombosis (Thrombus) 12/2023 - 04/2002
3	Aneurysm (Aneurysms) 09/2019 - 12/2014
3	Esophageal Neoplasms (Esophageal Cancer) 01/2016 - 01/2013
3	Obesity 10/2011 - 04/2005
2	Ischemic Stroke 12/2023 - 01/2019
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2023 - 01/2021
2	Microcephaly 10/2023 - 10/2022
2	Vaccinia 10/2023 - 04/2022
2	Multiple Myeloma 11/2021 - 11/2020
2	Intracranial Aneurysm (Cerebral Aneurysm) 09/2019 - 12/2014
2	Hemorrhage 05/2017 - 01/2014
2	Body Weight (Weight, Body) 03/2017 - 12/2007
2	Burns 03/2013 - 01/2012
2	Neoplasm Metastasis (Metastasis) 01/2012 - 05/2008
2	Hyperinsulinism (Hyperinsulinemia) 10/2011 - 07/2009
2	Type 2 Diabetes Mellitus (MODY) 08/2011 - 03/2007
2	Adenocarcinoma 07/2009 - 10/2002
2	Spasm (Spasms) 08/2008 - 04/2003
1	Smith-Lemli-Opitz Syndrome 04/2024
1	Renal Tubular Acidosis (Distal Renal Tubular Acidosis) 01/2024
1	Acidosis 01/2024
1	Sensorineural Hearing Loss 01/2024
1	Hearing Loss (Hearing Impairment) 01/2024
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2024
1	Fatty Liver 01/2024
1	Disease Progression 01/2024
1	Liver Diseases (Liver Disease) 01/2024
1	Pathologic Constriction (Stenosis) 12/2023
1	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 12/2023
1	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 10/2023
1	Stroke (Strokes) 10/2023
1	Central Nervous System Vascular Malformations (Dural Arteriovenous Fistula) 07/2023
1	Brain Abscess (Abscess, Brain) 07/2023
1	Hyperemia 07/2023
1	Wounds and Injuries (Trauma) 07/2023
1	COVID-19 01/2022
1	Chromosome 5q Deletion Syndrome 11/2021
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 11/2021
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 11/2021
1	Pontocerebellar Hypoplasia 01/2021
1	Colonic Pseudo-Obstruction (Ogilvie Syndrome) 10/2019
1	Brain Ischemia (Cerebral Ischemia) 01/2019
1	Reperfusion Injury 01/2019

Drug/Important Bio-Agent (IBA)

8	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 11/2014 - 04/2005
5	Proteins (Proteins, Gene)FDA Link 10/2022 - 12/2007
5	Insulin (Novolin)FDA Link 01/2012 - 05/2005
5	Cisplatin (Platino)FDA LinkGeneric 01/2012 - 02/2003
3	Glucose (Dextrose)FDA LinkGeneric 01/2012 - 07/2009
3	Carboplatin (JM8)FDA LinkGeneric 10/2009 - 04/2007
3	Methylnitrosourea (N-Methyl-N-nitrosourea)IBA 07/2009 - 12/2002
2	Phosphotransferases (Kinase)IBA 10/2023 - 04/2022
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2023 - 04/2022
2	pomalidomideIBA 11/2021 - 11/2020
2	Lenalidomide (CC 5013)FDA Link 11/2021 - 11/2020
2	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 01/2012
2	Methotrexate (Mexate)FDA LinkGeneric 07/2018 - 06/2004
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 11/2014 - 04/2013
2	Glycogen Synthase (Synthase I)IBA 03/2013 - 10/2011
2	Insulin Receptor Substrate ProteinsIBA 01/2012 - 03/2007
2	Acetylcholine (Acetylcholine Chloride)FDA Link 12/2008 - 08/2008
2	Fluorouracil (Carac)FDA LinkGeneric 05/2008 - 06/2004
2	Etoposide (VP 16)FDA LinkGeneric 05/2008 - 04/2007
2	Irinotecan (Camptosar)FDA LinkGeneric 06/2004 - 02/2003
2	CarcinogensIBA 03/2003 - 04/2002
1	CholesterolIBA 04/2024
1	7-dehydrocholesterolIBA 04/2024
1	Adenosine Triphosphatases (ATPase)IBA 01/2024
1	dirhodium tetraacetate (DRTA)IBA 01/2024
1	Adenosine Triphosphate (ATP)IBA 01/2024
1	Adenosine (Adenocard)FDA LinkGeneric 01/2024
1	beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA 01/2024
1	Dopamine (Intropin)FDA LinkGeneric 10/2023
1	MorpholinosIBA 10/2022
1	COVID-19 VaccinesIBA 01/2022
1	VaccinesIBA 01/2022
1	Transfer RNA (tRNA)IBA 01/2021
1	RNA Precursors (Precursor, mRNA)IBA 01/2021
1	Thalidomide (Thalomid)FDA Link 11/2020
1	Apoptosis Regulatory ProteinsIBA 01/2019
1	Monoclonal AntibodiesIBA 01/2019

Therapy/Procedure

8	Therapeutics 01/2024 - 04/2002
8	Gastrectomy 09/2018 - 01/2002
6	Drug Therapy (Chemotherapy) 07/2018 - 06/2004
4	Stents 05/2017 - 03/2004
4	Lymph Node Excision (Lymph Node Dissection) 01/2013 - 05/2008
3	Esophagectomy 05/2014 - 01/2014
2	Thrombectomy 12/2023 - 01/2019
2	Length of Stay 09/2018 - 12/2017
2	Combination Drug Therapy (Combination Chemotherapy) 10/2009 - 05/2008
1	Catheters 12/2023
1	Craniotomy 07/2023
1	Colectomy 10/2019
1	Decompression 09/2019