Naomi Shimizu Selected Research

Drug Therapy (Chemotherapy)

8/2022	Urothelial Carcinoma With Pulmonary Tumor Thrombotic Microangiopathy After Chemotherapy for Hodgkin Lymphoma.
7/2022	Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP) therapy increases carotid intima-media thickness and plaque score with von Willebrand factor activity elevation in patients with malignant lymphoma.
6/2022	PHOSPHATE exporter XPR1/SLC53A1 is required for the tumorigenicity of epithelial ovarian cancer.
4/2022	CRISPR/Cas9 Screening for Identification of Genes Required for the Growth of Ovarian Clear Cell Carcinoma Cells.
1/2020	Importance of doctor-initiated management of the balance between work and treatment for lung cancer patients: Results of a nationwide survey by the Japan Lung Cancer Society.
3/2018	PIK3CA and KRAS mutations in cell free circulating DNA are useful markers for monitoring ovarian clear cell carcinoma.
12/2017	Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Mucosa-associated Lymphoid Tissue Lymphoma.
8/2017	The Elevation of Cardio-Ankle Vascular Index in a Patient With Malignant Lymphoma Treated With a Combination Therapy of Rituximab and Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone.
10/2012	Circulating soluble LR11/SorLA levels are highly increased and ameliorated by chemotherapy in acute leukemias.
2/2012	Posterior reversible encephalopathy syndrome in an adult patient with acute lymphoblastic leukemia after remission induction chemotherapy.

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Naomi Shimizu Research Topics

Disease

10	Neoplasms (Cancer) 08/2022 - 03/2011
5	Carcinoma (Carcinomatosis) 08/2022 - 03/2018
4	POEMS Syndrome (Syndrome, POEMS) 10/2018 - 08/2008
4	Leukemia 04/2014 - 02/2012
4	Multiple Myeloma 02/2014 - 11/2007
3	Atherosclerosis 07/2022 - 12/2016
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019 - 10/2006
3	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 08/2017 - 10/2013
2	B-Cell Lymphoma (Lymphoma, B Cell) 11/2023 - 10/2014
2	Morbid Obesity 01/2023 - 01/2021
2	Lymphoma (Lymphomas) 07/2022 - 08/2017
2	Type 2 Diabetes Mellitus (MODY) 10/2021 - 07/2019
2	Sepsis (Septicemia) 10/2021 - 12/2014
2	Body Weight (Weight, Body) 10/2021 - 01/2021
2	Wilms Tumor (Wilm's Tumor) 11/2020 - 01/2016
2	Arteriosclerosis 08/2020 - 08/2017
2	Lung Neoplasms (Lung Cancer) 01/2020 - 02/2009
2	Hypertension (High Blood Pressure) 08/2017 - 02/2012
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 04/2014 - 02/2012
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2014 - 01/2007
2	Crush Injuries 11/2011 - 08/2009
1	Insulin Resistance 01/2023
1	Pathologic Complete Response 08/2022
1	Thrombotic Microangiopathies 08/2022
1	Heart Failure 08/2022
1	Hodgkin Disease (Hodgkin's Disease) 08/2022
1	Ovarian Epithelial Carcinoma 06/2022
1	Neoplasm Metastasis (Metastasis) 01/2022
1	Carcinogenesis 01/2022
1	Bacterial Infections (Bacterial Infection) 10/2021
1	Albuminuria 01/2021
1	Weight Loss (Weight Reduction) 01/2021
1	Pancytopenia 11/2020
1	Hydrocephalus (Hydrocephaly) 01/2019
1	Subependymal Glioma (Subependymoma) 01/2019
1	Brain Neoplasms (Brain Tumor) 01/2019
1	Urogenital Neoplasms 01/2019
1	Melanoma (Melanoma, Malignant) 01/2019
1	Pneumoperitoneum 01/2019
1	Glioblastoma (Glioblastoma Multiforme) 11/2018
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 04/2018
1	Endometriosis 03/2018
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2018
1	Inappropriate ADH Syndrome (SIADH) 12/2017
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 12/2017

Drug/Important Bio-Agent (IBA)

8	Biomarkers (Surrogate Marker)IBA 10/2021 - 10/2013
3	Rituximab (Mabthera)FDA Link 11/2023 - 08/2017
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 07/2022 - 12/2009
3	Semaphorin-3AIBA 09/2015 - 08/2009
2	Doxorubicin (Adriamycin)FDA LinkGeneric 07/2022 - 08/2017
2	Prednisolone (Predate)FDA LinkGeneric 07/2022 - 08/2017
2	Vincristine (Oncovin)FDA LinkGeneric 07/2022 - 08/2017
2	Azacitidine (5 Azacytidine)FDA Link 11/2020 - 04/2013
2	CytokinesIBA 01/2018 - 04/2016
2	Messenger RNA (mRNA)IBA 01/2018 - 04/2013
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 02/2017 - 12/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2016 - 08/2008
2	Proteins (Proteins, Gene)FDA Link 04/2016 - 04/2013
2	Interleukin-2 Receptors (IL 2 Receptor)IBA 03/2014 - 01/2014
2	Urokinase Plasminogen Activator ReceptorsIBA 03/2014 - 04/2013
1	Estrogens (Estrogen)FDA Link 11/2023
1	Prorenin ReceptorIBA 01/2023
1	von Willebrand FactorIBA 07/2022
1	Phosphates (Orthophosphate)IBA 06/2022
1	RNA Splicing FactorsIBA 01/2022
1	Adenosine Triphosphate (ATP)IBA 01/2022
1	RNA Helicases (RNA Helicase)IBA 01/2022
1	Glucose (Dextrose)FDA LinkGeneric 10/2021
1	EnzymesIBA 10/2021
1	AlbuminsIBA 01/2021
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2021
1	Hemoglobins (Hemoglobin)IBA 11/2020
1	Indicators and Reagents (Reagents)IBA 08/2020
1	Immune Checkpoint InhibitorsIBA 01/2020
1	Eicosapentaenoic AcidIBA 07/2019
1	BezafibrateIBA 07/2019
1	Fibric Acids (Fibrates)IBA 07/2019
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 07/2019
1	Bevacizumab (Avastin)FDA Link 01/2019
1	monooxyethylene trimethylolpropane tristearate (MTTS)IBA 01/2019
1	Lysine (L-Lysine)FDA Link 11/2018
1	Sirtuin 2IBA 11/2018
1	Inosine Triphosphate (ITP)IBA 04/2018
1	Thrombopoietin ReceptorsIBA 04/2018
1	SteroidsIBA 04/2018
1	Cell-Free Nucleic AcidsIBA 03/2018
1	OxysterolsIBA 01/2018
1	Arachidonate 12-Lipoxygenase (12 Lipoxygenase)IBA 01/2018
1	7-ketocholesterolIBA 01/2018
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2018
1	Vasopressins (Vasopressin)IBA 12/2017

Therapy/Procedure

11	Therapeutics 11/2023 - 02/2009
10	Drug Therapy (Chemotherapy) 08/2022 - 02/2012
5	Stem Cell Transplantation 10/2018 - 12/2009
2	Bariatric Surgery 10/2021 - 01/2021
1	Radiotherapy 01/2022
1	Glycemic Control 10/2021
1	Gastrectomy 01/2021
1	Ventriculoperitoneal Shunt 01/2019
1	Molecular Targeted Therapy 01/2019