Ian A Semple Selected Research

Mechanistic Target of Rapamycin Complex 1

1/2019	Concurrent activation of growth factor and nutrient arms of mTORC1 induces oxidative liver injury.
2/2016	Tumor suppressive role of sestrin2 during colitis and colon carcinogenesis.
3/2015	Sestrin2 inhibits mTORC1 through modulation of GATOR complexes.

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Ian A Semple Research Topics

Disease

2	Inflammation (Inflammations) 02/2016 - 09/2014
2	Obesity 03/2015 - 09/2014
1	Jaundice (Icterus) 01/2019
1	Liver Failure 01/2019
1	Bites and Stings (Sting) 10/2018
1	Colitis 02/2016
1	Carcinogenesis 02/2016
1	Colonic Neoplasms (Colon Cancer) 02/2016
1	Neoplasms (Cancer) 02/2016
1	Hypertension (High Blood Pressure) 09/2014
1	Insulin Resistance 09/2014

Drug/Important Bio-Agent (IBA)

3	Mechanistic Target of Rapamycin Complex 1IBA 01/2019 - 03/2015
2	SestrinsIBA 02/2016 - 03/2015
2	Proteins (Proteins, Gene)FDA Link 02/2016 - 09/2014
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 10/2018
1	InterferonsIBA 10/2018
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 09/2014
1	CalciumIBA 09/2014