Fumiko Sekiguchi Selected Research

Multiple Myeloma

1/2021	Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice.
1/2019	Critical role of Cav3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Fumiko Sekiguchi Research Topics

Disease

46	Hyperalgesia 06/2023 - 03/2004
34	Pain (Aches) 01/2024 - 07/2004
16	Visceral Pain 01/2023 - 03/2004
12	Neoplasms (Cancer) 01/2023 - 05/2006
11	Peripheral Nervous System Diseases (PNS Diseases) 01/2024 - 01/2016
11	Inflammation (Inflammations) 01/2023 - 12/2003
10	Cystitis 01/2023 - 10/2012
9	Pancreatitis 01/2023 - 05/2006
8	Hypersensitivity (Allergy) 01/2023 - 01/2016
7	Stroke (Strokes) 04/2004 - 04/2002
5	Neuralgia (Stump Neuralgia) 01/2023 - 07/2010
5	Intractable Pain 12/2022 - 01/2013
5	Breast Neoplasms (Breast Cancer) 05/2021 - 03/2002
4	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 10/2015
4	Edema (Dropsy) 01/2018 - 08/2006
4	Nociceptive Pain 02/2015 - 11/2010
3	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 05/2006
3	Interstitial Cystitis (Interstitial Cystitis, Chronic) 06/2020 - 02/2015
2	Multiple Myeloma 01/2021 - 01/2019
2	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 11/2020 - 05/2020
2	Disseminated Intravascular Coagulation 01/2019 - 11/2013
2	Referred Pain 01/2018 - 01/2012
2	Stomach Neoplasms (Stomach Cancer) 01/2016 - 05/2007
2	Adenocarcinoma 01/2010 - 12/2008

Drug/Important Bio-Agent (IBA)

17	HMGB1 Protein (HMG1)IBA 01/2022 - 11/2013
14	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 07/2019 - 11/2007
13	ThrombomodulinIBA 05/2021 - 11/2013
12	T-Type Calcium Channels (T-Type Calcium Channel)IBA 01/2023 - 03/2009
11	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2023 - 10/2012
10	Proteins (Proteins, Gene)FDA Link 12/2020 - 05/2007
9	CeruletideIBA 01/2023 - 05/2006
9	Protein Isoforms (Isoforms)IBA 12/2022 - 07/2012
9	sodium bisulfide (NaHS)IBA 01/2019 - 11/2007
8	EnzymesIBA 01/2023 - 05/2006
8	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2016
7	GasotransmittersIBA 01/2023 - 11/2007
7	CystathionineIBA 01/2023 - 10/2012
7	LyasesIBA 01/2023 - 10/2012
7	Thrombin FDA Link 01/2021 - 04/2014
7	NNC 55-0396IBA 06/2019 - 01/2012
7	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 07/2004
5	Cysteine (L-Cysteine)FDA Link 01/2023 - 11/2007
5	sodium sulfideIBA 01/2023 - 02/2014
5	Receptor for Advanced Glycation End ProductsIBA 01/2021 - 04/2014
5	Neutralizing AntibodiesIBA 12/2020 - 06/2004
4	ZincIBA 06/2023 - 02/2015
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 03/2022 - 01/2018
4	Nuclear Proteins (Protein, Nuclear)IBA 01/2021 - 11/2013
4	Toll-Like Receptor 4IBA 01/2021 - 04/2014
4	Phenobarbital (Luminal)FDA Link 01/2018 - 03/2004
4	Analgesics (Analgesic Drugs)IBA 01/2016 - 08/2006
4	MibefradilIBA 10/2012 - 11/2007
3	Calcium Channels (Calcium Channel)IBA 01/2023 - 01/2018
3	Adenosine Triphosphate (ATP)IBA 01/2022 - 08/2006
3	Dihydrotachysterol (AT 10)IBA 01/2021 - 08/2006
3	Bortezomib (Velcade)FDA Link 01/2021 - 01/2019
3	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 12/2020 - 04/2014
3	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2019 - 07/2012
3	AndrogensIBA 01/2019 - 10/2015
3	Minocycline (Cyclops)FDA LinkGeneric 10/2018 - 01/2017
3	LipopolysaccharidesIBA 01/2018 - 04/2014
3	Trastuzumab (Herceptin)FDA Link 07/2010 - 03/2002
3	Capecitabine (Xeloda)FDA Link 05/2007 - 03/2002
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2003 - 12/2002
3	Caffeine (No Doz)FDA LinkGeneric 04/2003 - 04/2002
2	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 06/2023 - 01/2018
2	Chelating AgentsIBA 06/2023 - 01/2018
2	Sulfides (Thioethers)IBA 01/2023 - 10/2009
2	Pimozide (Orap)FDA Link 12/2022 - 01/2021
2	Butyrates (Butyrate)IBA 02/2021 - 11/2020
2	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2021 - 01/2019
2	Vincristine (Oncovin)FDA LinkGeneric 12/2020 - 01/2016
2	PAR-2 ReceptorIBA 11/2020 - 11/2010
2	Substance PIBA 06/2020 - 01/2018
2	Immunosuppressive Agents (Immunosuppressants)IBA 05/2020 - 01/2017
2	Tacrolimus (Prograf)FDA LinkGeneric 05/2020 - 01/2017
2	CalcineurinIBA 05/2020 - 01/2017
2	Capsaicin (Zostrix)FDA Link 05/2020 - 03/2004
2	capsazepineIBA 05/2020 - 11/2010
2	Calcineurin InhibitorsIBA 05/2020 - 01/2017
2	AntioxidantsIBA 01/2020 - 02/2015
2	Acetylcysteine (Siran)FDA LinkGeneric 01/2020 - 10/2018
2	Dacarbazine (DIC)FDA LinkGeneric 01/2019 - 11/2013
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2017
2	AsparagineIBA 01/2019 - 01/2017
2	ethyl pyruvateIBA 10/2018 - 12/2017
2	Clodronic Acid (Clodronate)IBA 10/2018 - 12/2017
2	prolinedithiocarbamate (PDTC)IBA 10/2018 - 01/2018
2	2-furoyl-LIGRLO-amideIBA 01/2018 - 05/2006
2	Alanine (L-Alanine)FDA Link 01/2018 - 01/2018
2	Indomethacin (Indometacin)FDA LinkGeneric 01/2018 - 12/2002
2	CurcuminIBA 01/2018 - 01/2010
2	zinc chloride FDA Link 02/2015 - 07/2012
2	Ethosuximide (Zarontin)FDA LinkGeneric 02/2013 - 11/2007
2	propargylglycineIBA 07/2010 - 11/2007
2	3-cyanoalanineIBA 07/2010 - 11/2007

Therapy/Procedure

9	Drug Therapy (Chemotherapy) 03/2022 - 05/2007
7	Therapeutics 05/2021 - 03/2002
3	Oral Administration 02/2013 - 05/2006
2	Ligation 01/2018 - 01/2018