Nina Seiwert Selected Research

Temozolomide (Temodar)

1/2019	Immunological and mass spectrometry-based approaches to determine thresholds of the mutagenic DNA adduct O6-methylguanine in vivo.
8/2015	Lipoic acid inhibits the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) and triggers its depletion in colorectal cancer cells with concomitant autophagy induction.

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Nina Seiwert Research Topics

Disease

11	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 08/2015
11	Neoplasms (Cancer) 01/2022 - 08/2015
5	Carcinogenesis 01/2021 - 01/2018
3	Inflammation (Inflammations) 01/2021 - 01/2018
1	Dysbiosis 01/2021
1	Intestinal Neoplasms (Intestinal Cancer) 11/2020
1	Reperfusion Injury 10/2019
1	Hypoxia (Hypoxemia) 01/2018
1	Genomic Instability 01/2017
1	Chromosomal Instability (Chromosome Stability) 12/2016
1	Chromosome Aberrations (Chromosome Abnormalities) 12/2016

Drug/Important Bio-Agent (IBA)

4	DNA (Deoxyribonucleic Acid)IBA 06/2021 - 12/2016
4	Heme (Haem)IBA 01/2021 - 01/2020
3	IronIBA 01/2021 - 01/2020
3	Thioctic Acid (Lipoic Acid)IBA 01/2019 - 08/2015
2	Antineoplastic Agents (Antineoplastics)IBA 01/2022 - 01/2019
2	Fluorouracil (Carac)FDA LinkGeneric 01/2022 - 10/2015
2	AzoxymethaneIBA 01/2021 - 01/2018
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2021 - 01/2018
2	MethyltransferasesIBA 01/2021 - 08/2015
2	Dextrans (Dextran)FDA Link 01/2021 - 01/2018
2	Temozolomide (Temodar)FDA LinkGeneric 01/2019 - 08/2015
1	Irinotecan (Camptosar)FDA LinkGeneric 01/2022
1	devimistatIBA 01/2022
1	3-hydroxycholest-7-ene-14-carbaldehydeIBA 01/2021
1	CurcuminIBA 01/2021
1	MicellesIBA 01/2021
1	Nitroso CompoundsIBA 01/2021
1	16S Ribosomal RNAIBA 01/2021
1	SolutionsIBA 01/2021
1	DNA Repair EnzymesIBA 01/2021
1	Drinking WaterIBA 01/2021
1	A-factor (Streptomyces)IBA 11/2020
1	tert-ButylhydroperoxideIBA 10/2019
1	Tumor Suppressor Protein p53IBA 01/2019
1	Oxidoreductases (Dehydrogenase)IBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	CytokinesIBA 01/2018
1	Cyclin D1IBA 01/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 01/2017
1	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 12/2016
1	CarcinogensIBA 12/2016
1	Glutathione (Reduced Glutathione)IBA 08/2015
1	Proteins (Proteins, Gene)FDA Link 08/2015
1	SmokeIBA 08/2015
1	DisulfidesIBA 08/2015
1	Alkylating AgentsIBA 08/2015

Therapy/Procedure

5	Therapeutics 01/2022 - 08/2015
2	Drug Therapy (Chemotherapy) 06/2021 - 08/2015