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Stefanie Schrauwen Selected Research

Neoplasms (Cancer)

1/2019Addition of IMP3 to L1CAM for discrimination between low- and high-grade endometrial carcinomas: a European Network for Individualised Treatment of Endometrial Cancer collaboration study.
1/2018Added Value of Estrogen Receptor, Progesterone Receptor, and L1 Cell Adhesion Molecule Expression to Histology-Based Endometrial Carcinoma Recurrence Prediction Models: An ENITEC Collaboration Study.
10/2016Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.
10/2015Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies.
8/2015The antitumor effect of metformin with and without carboplatin on primary endometrioid endometrial carcinoma in vivo.
7/2015Dual blockade of PI3K/AKT/mTOR (NVP-BEZ235) and Ras/Raf/MEK (AZD6244) pathways synergistically inhibit growth of primary endometrioid endometrial carcinoma cultures, whereas NVP-BEZ235 reduces tumor growth in the corresponding xenograft models.
3/2015Microsatellite instable and microsatellite stable primary endometrial carcinoma cells and their subcutaneous and orthotopic xenografts recapitulate the characteristics of the corresponding primary tumor.
3/2015Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk.
8/2014Mismatch repair deficiency endows tumors with a unique mutation signature and sensitivity to DNA double-strand breaks.
2/2013Increased expression of placental growth factor in high-grade endometrial carcinoma.

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Stefanie Schrauwen Research Topics

Disease

10Neoplasms (Cancer)
01/2019 - 02/2013
9Endometrial Neoplasms (Endometrial Cancer)
01/2019 - 02/2013
3Endometrioid Carcinoma
01/2019 - 02/2013
2Carcinoma (Carcinomatosis)
01/2019 - 02/2013
2Neoplasm Metastasis (Metastasis)
09/2017 - 02/2013
1Carcinosarcoma
10/2016
1Uterine Neoplasms (Uterine Cancer)
10/2016
1Microsatellite Instability
10/2015
1Turcot syndrome
08/2014

Drug/Important Bio-Agent (IBA)

3Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA
01/2019 - 09/2016
3Messenger RNA (mRNA)IBA
01/2019 - 02/2013
2Proteins (Proteins, Gene)FDA Link
01/2019 - 02/2013
2dactolisibIBA
10/2015 - 07/2015
2Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
10/2015 - 07/2015
2AZD 6244IBA
10/2015 - 07/2015
1Carrier Proteins (Binding Protein)IBA
01/2019
1Insulin-Like Growth Factor II (Somatomedin A)IBA
01/2019
1Estrogen ReceptorsIBA
01/2018
1Progesterone Receptors (Progesterone Receptor)IBA
01/2018
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
10/2016
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
10/2016
1Estradiol (Delestrogen)FDA LinkGeneric
02/2016
1Keratins (Keratin)IBA
10/2015
1VimentinIBA
10/2015
1Metformin (Glucophage)FDA LinkGeneric
08/2015
1Carboplatin (JM8)FDA LinkGeneric
08/2015
1Telomerase (Telomerase Reverse Transcriptase)IBA
03/2015
1Hepatocyte Nuclear Factor 1IBA
03/2015
1DNA (Deoxyribonucleic Acid)IBA
08/2014
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
08/2014
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
02/2013
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
02/2013

Therapy/Procedure

3Therapeutics
10/2015 - 02/2013
2Drug Therapy (Chemotherapy)
09/2017 - 10/2015