Benjamin Schmid Selected Research

Frontotemporal Dementia (Semantic Dementia)

11/2021	Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3.
1/2017	Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B.
11/2016	Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.
11/2016	Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia.
11/2016	Generation of an isogenic, gene-corrected iPSC line from a symptomatic 57-year-old female patient with frontotemporal dementia caused by a P301L mutation in the microtubule associated protein tau (MAPT) gene.
11/2016	Generation of an isogenic, gene-corrected iPSC line from a pre-symptomatic 28-year-old woman with an R406W mutation in the microtubule associated protein tau (MAPT) gene.

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Benjamin Schmid Research Topics

Disease

10	Alzheimer Disease (Alzheimer's Disease) 04/2024 - 01/2010
6	Frontotemporal Dementia (Semantic Dementia) 11/2021 - 11/2016
5	Chromosome 3-Linked Frontotemporal Dementia 10/2023 - 01/2016
5	Inflammation (Inflammations) 03/2022 - 01/2019
4	Neoplasms (Cancer) 03/2024 - 02/2008
4	Colitis 03/2022 - 11/2019
3	Parkinson Disease (Parkinson's Disease) 01/2021 - 06/2014
3	Dementia (Dementias) 01/2012 - 01/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2024 - 01/2017
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2022 - 01/2020
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 11/2019
2	Lewy Body Disease (Lewy Body Dementia) 01/2010 - 01/2010
1	Prostatic Neoplasms (Prostate Cancer) 03/2024
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023
1	Cardiomyopathies (Cardiomyopathy) 10/2022
1	Colorectal Neoplasms (Colorectal Cancer) 03/2022
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	Glioblastoma (Glioblastoma Multiforme) 01/2021
1	Fibrosis (Cirrhosis) 01/2017
1	Gaucher Disease (Gaucher's Disease) 06/2014
1	Osteosarcoma (Osteogenic Sarcoma) 04/2013

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 10/2023 - 02/2008
4	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 11/2016 - 11/2016
2	Apolipoproteins E (ApoE)IBA 04/2024 - 01/2021
2	CalciumIBA 10/2021 - 06/2014
2	SynucleinsIBA 01/2021 - 01/2010
2	EnzymesIBA 11/2020 - 07/2018
2	AcidsIBA 01/2020 - 06/2014
2	Presenilin-1IBA 11/2016 - 01/2016
2	Endosomal Sorting Complexes Required for TransportIBA 01/2016 - 01/2016
2	Amyloid beta-PeptidesIBA 05/2010 - 01/2010
1	Androgen Receptors (Androgen Receptor)IBA 03/2024
1	AndrogensIBA 03/2024
1	Glutamine (L-Glutamine)FDA Link 10/2023
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2022
1	DesminIBA 10/2022
1	Collagen Type VIIBA 03/2022
1	Collagen Type I (Type I Collagen)IBA 03/2022
1	Histones (Histone)IBA 01/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021
1	Apolipoprotein E4IBA 10/2021
1	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2021
1	ColforsinIBA 01/2021
1	ApolipoproteinsIBA 01/2021
1	1- (5- Isoquinolinesulfonyl)- 2- Methylpiperazine (H 7)IBA 01/2021
1	Cyclic AMP (AMP, Cyclic)IBA 01/2021
1	BucladesineIBA 01/2021
1	Dextrans (Dextran)FDA Link 01/2021
1	Arginine (L-Arginine)FDA Link 11/2020
1	ArginaseIBA 11/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Protein Deglycase DJ-1IBA 01/2020
1	Imatinib Mesylate (Gleevec)FDA Link 11/2019
1	cadherin 5IBA 11/2019
1	ChemokinesIBA 01/2019
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2019
1	CytokinesIBA 01/2019
1	Serine Proteases (Serine Protease)IBA 01/2019
1	CationsIBA 10/2018
1	Oxygen (Dioxygen)IBA 01/2017
1	IronIBA 01/2017
1	GadoliniumIBA 01/2017
1	Glucosylceramidase (Glucocerebrosidase)IBA 06/2014
1	Messenger RNA (mRNA)IBA 04/2013
1	Prealbumin (Transthyretin)IBA 01/2012
1	Peptides (Polypeptides)IBA 05/2010
1	Amyloid (Amyloid Fibrils)IBA 01/2010
1	Neprilysin (Neutral Endopeptidase)IBA 01/2010
1	Cystatin CIBA 01/2010
1	CarcinogensIBA 02/2008
1	anthraceneIBA 02/2008
1	Codon (Codons)IBA 02/2008
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 02/2008
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 02/2008

Therapy/Procedure

1	Hematopoietic Stem Cell Transplantation 01/2023
1	Aftercare (After-Treatment) 01/2021
1	Drug Therapy (Chemotherapy) 01/2021
1	Fecal Microbiota Transplantation 11/2020