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E A Sausville Selected Research

Ataxia Telangiectasia (Louis Bar Syndrome)

2/2000The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01.

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E A Sausville Research Topics

Disease

23Neoplasms (Cancer)
04/2004 - 02/2000
5Breast Neoplasms (Breast Cancer)
08/2001 - 06/2000
2Carcinoma (Carcinomatosis)
04/2002 - 05/2000
1Hodgkin Disease (Hodgkin's Disease)
01/2016
1Renal Cell Carcinoma (Grawitz Tumor)
04/2004
1Acquired Immunodeficiency Syndrome (AIDS)
04/2002
1Hematologic Neoplasms (Hematological Malignancy)
04/2002
1Pathologic Constriction (Stenosis)
11/2001
1Hemolysis
09/2001
1Melanoma (Melanoma, Malignant)
09/2001
1Colonic Neoplasms (Colon Cancer)
06/2001
1Rhabdomyosarcoma
06/2001
1Diarrhea
02/2001
1Carcinogenesis
01/2001
1Alzheimer Disease (Alzheimer's Disease)
10/2000
1Leukemia
06/2000
1Lymphoma (Lymphomas)
05/2000
1B-Cell Lymphoma (Lymphoma, B Cell)
04/2000
1Ataxia Telangiectasia (Louis Bar Syndrome)
02/2000
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2000
1Blast Crisis (Blast Phase)
01/2000

Drug/Important Bio-Agent (IBA)

5alvocidib (flavopiridol)IBA
04/2002 - 07/2000
4Cyclin-Dependent Kinases (cdk Proteins)IBA
02/2001 - 07/2000
3Cytochrome P-450 CYP1A1 (CYP1A1)IBA
04/2004 - 09/2000
3Proteins (Proteins, Gene)FDA Link
04/2002 - 02/2000
37-hydroxystaurosporine (UCN 01)IBA
04/2002 - 02/2000
3Phosphotransferases (Kinase)IBA
11/2001 - 01/2000
3Immunotoxins (Immunotoxin)IBA
05/2000 - 02/2000
2Messenger RNA (mRNA)IBA
02/2001 - 01/2001
2Monoclonal AntibodiesIBA
10/2000 - 04/2000
2Caspase 3 (Caspase-3)IBA
06/2000 - 01/2000
2Cytochromes c (Cytochrome c)IBA
06/2000 - 01/2000
1NivolumabIBA
01/2016
1aminoflavoneIBA
04/2004
1DepsipeptidesIBA
04/2002
1hydroxypropyl methacrylateIBA
09/2001
1Macrocyclic LactamsIBA
08/2001
1Sirolimus (Rapamycin)FDA Link
06/2001
1temsirolimusFDA Link
06/2001
1EstersIBA
06/2001
1Eukaryotic Initiation Factor-4EIBA
06/2001
1Indicators and Reagents (Reagents)IBA
05/2001
1Antineoplastic Agents (Antineoplastics)IBA
03/2001
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
03/2001
1Transforming Growth Factor beta (TGF-beta)IBA
02/2001
1entinostat (MS 275)IBA
02/2001
1Histone Deacetylase InhibitorsIBA
02/2001
1Transforming Growth Factor-beta Type I ReceptorIBA
02/2001
1Transforming Growth Factor-beta Type II ReceptorIBA
02/2001
1Transforming Growth Factors (Transforming Growth Factor)IBA
02/2001
1Histone Deacetylases (Histone Deacetylase)IBA
02/2001
1Histones (Histone)IBA
02/2001
1Adenosine Triphosphate (ATP)IBA
01/2001
1FlavonoidsIBA
01/2001
1ranpirnase (Pannon)IBA
01/2001
1RNA (Ribonucleic Acid)IBA
01/2001
1Telomerase (Telomerase Reverse Transcriptase)IBA
01/2001
1Cytotoxins (Cytolysins)IBA
12/2000
1Immunoconjugates (Immunoconjugate)IBA
10/2000
1Trastuzumab (Herceptin)FDA Link
10/2000
1geldanamycinIBA
10/2000
1EnzymesIBA
10/2000
1alsterpaulloneIBA
10/2000
1Glycogen Synthase Kinase 3 betaIBA
10/2000
1Carrier Proteins (Binding Protein)IBA
10/2000
1NSC 674495IBA
09/2000
1olomoucineIBA
07/2000
1purineIBA
07/2000
1NU2058IBA
07/2000
1pyrimidineIBA
07/2000
14- cyclohexylmethoxy- 5- nitrosopyrimidine- 2,6- diamineIBA
07/2000
1Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric
06/2000
1Paclitaxel (Taxol)FDA LinkGeneric
06/2000
1Brefeldin AIBA
05/2000
1N-caproylsphingosineIBA
05/2000
1Glycoproteins (Glycoprotein)IBA
05/2000
1Fluorescent Dyes (Fluorescent Probes)IBA
05/2000
1Coloring Agents (Dyes)IBA
05/2000
1Carcinoembryonic AntigenIBA
05/2000
1KRN 5500 (KRN5500)IBA
05/2000
14,4- difluoro- 4- bora- 3a,4a- diaza- s- indacene (BODIPY)IBA
05/2000
1RicinIBA
04/2000
1combotoxIBA
04/2000
1Complementary DNA (cDNA)IBA
03/2000
1DNA (Deoxyribonucleic Acid)IBA
02/2000
1Protein Kinase InhibitorsIBA
02/2000
1LigandsIBA
02/2000
1Peptides (Polypeptides)IBA
02/2000
1Caspase 9IBA
01/2000
1tyrphostin AG957IBA
01/2000
1NSC 680410IBA
01/2000

Therapy/Procedure

6Therapeutics
04/2002 - 02/2000
3Drug Therapy (Chemotherapy)
08/2001 - 03/2000
1Stem Cell Transplantation
01/2016