Silvia Santamarina-Fojo Selected Research

Apolipoproteins B (ApoB)

4/2009	Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.
1/2007	Hepatic ABCG5/G8 overexpression reduces apoB-lipoproteins and atherosclerosis when cholesterol absorption is inhibited.
1/2007	Lipolytic and ligand-binding functions of hepatic lipase protect against atherosclerosis in LDL receptor-deficient mice.
10/2004	The ligand-binding function of hepatic lipase modulates the development of atherosclerosis in transgenic mice.
8/2003	Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice.
1/2002	The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.

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Silvia Santamarina-Fojo Research Topics

Disease

15	Atherosclerosis 04/2009 - 01/2002
3	Tangier Disease 04/2004 - 04/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2003 - 04/2003
1	Hyperlipidemias (Hyperlipidemia) 12/2006
1	Hepatocellular Carcinoma (Hepatoma) 10/2005
1	Coronary Artery Disease (Coronary Atherosclerosis) 08/2003
1	Hypercholesterolemia 08/2003
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 08/2003
1	Sitosterolemia 04/2003

Drug/Important Bio-Agent (IBA)

9	Lipoproteins (Lipoprotein)IBA 04/2009 - 01/2002
9	CholesterolIBA 01/2007 - 01/2002
7	LipidsIBA 12/2006 - 01/2002
6	Apolipoproteins B (ApoB)IBA 04/2009 - 01/2002
6	Apolipoproteins E (ApoE)IBA 12/2006 - 01/2002
4	HDL CholesterolIBA 04/2009 - 04/2003
4	Lipase (Acid Lipase)FDA Link 01/2007 - 08/2003
3	ATP-Binding Cassette Transporters (ABC Transporters)IBA 06/2003 - 01/2002
2	LigandsIBA 01/2007 - 10/2004
2	LDL Receptors (LDL Receptor)IBA 01/2007 - 05/2004
2	SterolsIBA 01/2007 - 05/2004
2	oxidized low density lipoproteinIBA 12/2006 - 08/2003
2	Proteins (Proteins, Gene)FDA Link 10/2004 - 08/2003
2	Apolipoprotein A-I (Apolipoprotein A1)IBA 04/2004 - 04/2003
2	HDL LipoproteinsIBA 08/2003 - 04/2003
1	Ezetimibe (Zetia)FDA Link 01/2007
1	Biomarkers (Surrogate Marker)IBA 12/2006
1	Messenger RNA (mRNA)IBA 10/2005
1	OxysterolsIBA 10/2005
1	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 10/2004
1	EnzymesIBA 10/2004
1	AminesIBA 04/2004
1	3- beta- (2- (diethylamino)ethoxy)androst- 5- en- 17- oneIBA 04/2004
1	SphingomyelinsIBA 04/2004
1	Adenosine Triphosphate (ATP)IBA 08/2003
1	Triglycerides (Triacylglycerol)IBA 08/2003
1	CholatesIBA 08/2003
1	Phosphatidylcholine-Sterol O-Acyltransferase (Lecithin Cholesterol Acyltransferase)IBA 08/2003
1	ApolipoproteinsIBA 06/2003
1	paraform (paraformaldehyde)IBA 04/2003