Aziz Sancar Selected Research

Therapeutics

1/2019	Differential damage and repair of DNA-adducts induced by anti-cancer drug cisplatin across mouse organs.
6/2009	Circadian regulation of DNA excision repair: implications for chrono-chemotherapy.
7/2008	cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.

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Aziz Sancar Research Topics

Disease

22	Neoplasms (Cancer) 02/2024 - 10/2003
6	Genomic Instability 01/2024 - 06/2003
5	Ataxia Telangiectasia (Louis Bar Syndrome) 04/2016 - 11/2009
3	Xeroderma Pigmentosum (Kaposi's Disease) 12/2019 - 02/2009
2	Liver Neoplasms (Liver Cancer) 10/2023 - 09/2023
2	Carcinogenesis 01/2020 - 04/2016
2	Colorectal Neoplasms (Colorectal Cancer) 01/2020 - 07/2008
2	Lung Neoplasms (Lung Cancer) 01/2019 - 01/2017
2	Melanoma (Melanoma, Malignant) 04/2015 - 06/2010
2	Skin Neoplasms (Skin Cancer) 04/2015 - 10/2003
2	Complementation Group E Xeroderma Pigmentosum 11/2005 - 01/2002
1	Complementation Group C Xeroderma Pigmentosum 03/2024
1	Homocystinuria 01/2021
1	Shock 01/2020
1	Cockayne Syndrome (Syndrome, Cockayne) 11/2019
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2016
1	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2016
1	Bites and Stings (Sting) 05/2015
1	Sunburn 04/2015
1	Erythema 04/2015
1	Sleep Deprivation 12/2002
1	Retinal Degeneration 07/2002

Drug/Important Bio-Agent (IBA)

17	DNA (Deoxyribonucleic Acid)IBA 01/2018 - 06/2003
8	Cisplatin (Platino)FDA LinkGeneric 10/2023 - 06/2009
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 11/2005
5	Phosphotransferases (Kinase)IBA 04/2016 - 11/2009
4	PlatinumIBA 02/2024 - 07/2008
4	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2020 - 07/2008
4	CryptochromesIBA 06/2011 - 07/2002
3	DNA AdductsIBA 03/2024 - 01/2019
3	Pyrimidine DimersIBA 08/2012 - 01/2002
2	NucleotidesIBA 01/2021 - 01/2020
2	Checkpoint Kinase 1IBA 10/2012 - 06/2011
2	Carrier Proteins (Binding Protein)IBA 06/2011 - 12/2002
2	DDBIBA 11/2005 - 01/2002
1	PyrimidinonesIBA 01/2024
1	pyrimidineIBA 01/2024
1	Diethylnitrosamine (N-Nitrosodiethylamine)IBA 10/2023
1	MycotoxinsIBA 09/2023
1	Aflatoxin B1 (Aflatoxin B)IBA 09/2023
1	8-Hydroxy-2'-DeoxyguanosineIBA 12/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020
1	Oncogene Proteins (Oncogene Protein)IBA 01/2020
1	Transcription Factor TFIIHIBA 12/2019
1	Replication Protein AIBA 12/2019
1	RNA (Ribonucleic Acid)IBA 12/2019
1	Staphylococcal Protein A (Protein A)IBA 11/2019
1	deoxyguanylyl-(3'-5')-guanosineIBA 01/2018
1	Polycyclic Aromatic Hydrocarbons (Polynuclear Aromatic Hydrocarbons)IBA 01/2017
1	Benzo(a)pyreneIBA 01/2017
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 04/2016
1	Protein Kinases (Protein Kinase)IBA 04/2016
1	ChromatinIBA 04/2016
1	RibonucleotidesIBA 12/2015
1	Ribonucleases (Ribonuclease)IBA 12/2015
1	EnzymesIBA 12/2015
1	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 05/2015
1	Transcription Factors (Transcription Factor)IBA 05/2015
1	InterferonsIBA 05/2015
1	CytokinesIBA 04/2015
1	DNA Repair EnzymesIBA 01/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2013
1	Single-Stranded DNA (DNA, Single Stranded)IBA 10/2012
1	DNA-Activated Protein KinaseIBA 06/2011
1	A-Form DNA (A-DNA)IBA 02/2009
1	OxalatesIBA 07/2008
1	cis-diammine(pyridine)chloroplatinum(II)IBA 07/2008
1	1,2-cyclohexanediamine (dach)IBA 07/2008
1	CationsIBA 07/2008
1	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2005
1	AlbuminsIBA 12/2002
1	Messenger RNA (mRNA)IBA 12/2002

Therapy/Procedure

7	Drug Therapy (Chemotherapy) 01/2020 - 06/2009
3	Therapeutics 01/2019 - 07/2008