Akiyoshi Saitoh Selected Research

Schizophrenia (Dementia Praecox)

10/2023

Hydrogen sulfide and polysulfides induce GABA/glutamate/D-serine release, facilitate hippocampal LTP, and regulate behavioral hyperactivity.

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Akiyoshi Saitoh Research Topics

Disease

7	Hyperalgesia 01/2022 - 11/2004
6	Cough 09/2008 - 04/2003
5	Anxiety Disorders (Anxiety Disorder) 12/2023 - 01/2015
4	Mood Disorders (Mood Disorder) 01/2023 - 04/2003
3	Alzheimer Disease (Alzheimer's Disease) 10/2023 - 01/2019
3	Amnesia (Dissociative Amnesia) 12/2022 - 01/2013
3	Cognitive Dysfunction 12/2022 - 04/2006
2	Hypersensitivity (Allergy) 10/2023 - 01/2022
2	Catalepsy 01/2020 - 04/2018
2	Major Depressive Disorder (Major Depressive Disorders) 01/2020 - 04/2010
2	Treatment-Resistant Depressive Disorder 04/2013 - 04/2003
2	Painful Neuropathy 04/2006 - 09/2005
1	Schizophrenia (Dementia Praecox) 10/2023
1	Memory Disorders (Memory Loss) 10/2023
1	Dementia (Dementias) 10/2023
1	Neuroinflammatory Diseases 01/2023
1	Delirium 10/2022
1	Neoplasms (Cancer) 10/2022
1	COVID-19 03/2022
1	Virus Diseases (Viral Diseases) 03/2022
1	Alcoholism (Alcohol Abuse) 01/2022
1	Visceral Pain 01/2022
1	Tremor (Tremors) 01/2021
1	Chronic Pain 01/2021
1	Body Weight (Weight, Body) 01/2019
1	Weight Loss (Weight Reduction) 01/2017
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2014
1	Mental Disorders (Mental Disorder) 11/2013
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2011

Drug/Important Bio-Agent (IBA)

6	Antidepressive Agents (Antidepressants)IBA 01/2023 - 04/2003
6	KNT 127IBA 01/2023 - 01/2017
6	Capsaicin (Zostrix)FDA Link 01/2022 - 04/2003
5	delta Opioid Receptors (delta Opioid Receptor)IBA 12/2023 - 09/2008
4	Riluzole FDA LinkGeneric 10/2015 - 01/2011
4	Antitussive Agents (Antitussives)FDA Link 09/2008 - 04/2003
3	Oxycodone (Oxycontin)FDA LinkGeneric 10/2022 - 11/2005
3	Anti-Anxiety Agents (Anxiolytics)IBA 01/2022 - 01/2013
3	Streptozocin (Streptozotocin)FDA Link 04/2006 - 11/2005
2	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 10/2023 - 04/2014
2	Oxytocin (Pitocin)FDA LinkGeneric 10/2023 - 12/2022
2	AcidsIBA 01/2021 - 12/2005
2	4- (alpha- (4- allyl- 2,5- dimethyl- 1- piperazinyl)- 3- methoxybenzyl)- N,N- diethylbenzamideIBA 01/2021 - 04/2018
2	Vincristine (Oncovin)FDA LinkGeneric 04/2006 - 09/2005
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 04/2006 - 09/2005
2	Mexiletine (Mexitil)FDA LinkGeneric 04/2006 - 11/2004
1	AnkyrinsIBA 10/2023
1	Amyloidogenic ProteinsIBA 10/2023
1	Morphine (MS Contin)FDA LinkGeneric 10/2022
1	Tapentadol FDA Link 10/2022
1	Opioid Analgesics (Opioids)IBA 10/2022
1	TabletsIBA 10/2022
1	Alanine (L-Alanine)FDA Link 03/2022
1	Sulfhydryl Compounds (Thiols)IBA 03/2022
1	Glutathione (Reduced Glutathione)IBA 03/2022
1	Acetylcysteine (Siran)FDA LinkGeneric 03/2022
1	Disulfiram (Antabuse)FDA Link 01/2022
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2022
1	BenzodiazepinesIBA 01/2022
1	Charcoal (Charbon)IBA 01/2022
1	Diazepam (Valium)FDA LinkGeneric 01/2022
1	alphaxalone (alfaxalone)IBA 01/2022
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2022
1	alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA 01/2021
1	Glutamic Acid (Glutamate)FDA Link 01/2021
1	6-Cyano-7-nitroquinoxaline-2,3-dione (6 Cyano 7 nitroquinoxaline 2,3 dione)IBA 01/2021
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2020
1	4-hydroxyphenylethanolIBA 01/2019
1	Amyloid (Amyloid Fibrils)IBA 01/2019
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2017
1	Therapeutic UsesIBA 01/2017
1	Sertraline (Zoloft)FDA LinkGeneric 03/2015
1	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 04/2013
1	Glucagon (Glukagon)FDA Link 04/2013
1	Adrenocorticotropic Hormone (ACTH)FDA Link 04/2013
1	MorphinansIBA 09/2008
1	methanesulfonic acid (methanesulfonate)IBA 09/2008
1	NG-Nitroarginine Methyl Ester (L-NAME)IBA 04/2006
1	Tetrodotoxin (Tetradotoxin)IBA 04/2006
1	Sodium Channels (Sodium Channel)IBA 04/2006
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 03/2006
1	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 03/2006
1	AminesIBA 03/2006
1	LigandsIBA 03/2006
1	AerosolsIBA 03/2006
1	TRPV1 receptorIBA 03/2006
1	N- (2- methyl- 3- hydroxyphenyl)- 5,8,11,14- eicosatetraenamideIBA 03/2006
1	SolutionsIBA 03/2006
1	AM 251 (AM251)IBA 03/2006
1	anandamide (arachidonylethanolamide)IBA 03/2006
1	capsazepineIBA 03/2006
1	Membrane Transport Proteins (Biological Pump)IBA 03/2006
1	CannabinoidsIBA 03/2006
1	Cibacron Blue F 3GAIBA 12/2005
1	Purinergic Receptors (Receptors, Purine)IBA 12/2005
1	Adenosine Triphosphate (ATP)IBA 12/2005
1	Irritants (Vesicants)IBA 12/2005
1	pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acidIBA 12/2005
1	2',3'-O-(2,4,6-trinitrophenyl)adenosine 5'-triphosphateIBA 12/2005

Therapy/Procedure

1	Therapeutics 01/2017
1	Aftercare (After-Treatment) 03/2015