Guy A Rutter Selected Research

zinc-binding protein (zinc binding protein)

1/2023	Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice.
11/2022	Lack of ZnT8 protects pancreatic islets from hypoxia- and cytokine-induced cell death.
1/2018	Sensors for measuring subcellular zinc pools.
1/2017	The Role of Oxidative Stress and Hypoxia in Pancreatic Beta-Cell Dysfunction in Diabetes Mellitus.
12/2016	Zinc and diabetes.
8/2015	The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion.
8/2015	The zinc transporter ZIP12 regulates the pulmonary vascular response to chronic hypoxia.
1/2010	Think zinc: New roles for zinc in the control of insulin secretion.
9/2009	Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

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Guy A Rutter Research Topics

Disease

62	Type 2 Diabetes Mellitus (MODY) 02/2024 - 08/2002
14	Obesity 01/2022 - 07/2006
13	Insulin Resistance 04/2024 - 06/2008
8	Body Weight (Weight, Body) 04/2024 - 09/2009
7	Hyperglycemia 04/2024 - 04/2005
7	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023 - 06/2008
7	Diabetes Mellitus 12/2018 - 10/2003
6	Hypoglycemia (Reactive Hypoglycemia) 01/2023 - 06/2005
6	Neoplasms (Cancer) 01/2023 - 06/2010
6	Hypoxia (Hypoxemia) 11/2022 - 01/2010
6	Insulinoma 01/2022 - 04/2003
5	Weight Loss (Weight Reduction) 12/2022 - 01/2018
4	Glucose Intolerance 01/2022 - 12/2014
4	Pancreatitis 01/2016 - 03/2008
3	COVID-19 01/2023 - 01/2020
3	Inflammation (Inflammations) 11/2022 - 01/2020
3	Weight Gain 01/2021 - 06/2010
3	Nausea 01/2018 - 12/2015
2	Infections 01/2020 - 03/2004
2	Pulmonary Hypertension 01/2018 - 08/2015
2	Wolfram Syndrome (Syndrome, Wolfram) 02/2015 - 01/2008
2	Neuroblastoma 02/2015 - 01/2008
2	Peutz-Jeghers Syndrome (Polyposis, Hamartomatous Intestinal) 11/2014 - 06/2010
2	Hyperinsulinism (Hyperinsulinemia) 07/2012 - 09/2007
1	Glycosuria 04/2024
1	Colorectal Neoplasms (Colorectal Cancer) 12/2023
1	Islet Cell Adenoma (Islet Cell Tumors) 01/2023
1	Disease Progression 01/2023
1	Hyperhomocysteinemia 01/2022
1	Homocystinuria 01/2022
1	Peripheral Nerve Injuries 11/2021
1	Body Weight Changes 08/2020

Drug/Important Bio-Agent (IBA)

37	Glucose (Dextrose)FDA LinkGeneric 04/2024 - 08/2002
28	Insulin (Novolin)FDA Link 02/2024 - 08/2002
10	Proteins (Proteins, Gene)FDA Link 04/2024 - 03/2004
9	zinc-binding protein (zinc binding protein)IBA 01/2023 - 09/2009
8	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2021 - 11/2014
7	Hormones (Hormone)IBA 01/2018 - 07/2006
6	Glucagon-Like Peptide-1 ReceptorIBA 01/2023 - 01/2018
6	ZincIBA 01/2023 - 08/2015
6	AMP-Activated Protein KinasesIBA 01/2022 - 06/2004
6	Phosphotransferases (Kinase)IBA 01/2018 - 06/2010
5	Glucagon (Glukagon)FDA Link 12/2018 - 06/2005
4	CytokinesIBA 04/2024 - 11/2022
4	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2003
3	C-PeptideIBA 01/2024 - 01/2021
3	LipidsIBA 01/2023 - 11/2006
3	Zinc Transporter 8IBA 01/2023 - 08/2014
3	Hypoglycemic Agents (Hypoglycemics)IBA 11/2022 - 09/2007
3	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2016
3	GlucocorticoidsIBA 01/2022 - 01/2018
3	Adenosine Triphosphate (ATP)IBA 10/2020 - 06/2008
3	Messenger RNA (mRNA)IBA 08/2020 - 08/2014
3	Proglucagon (Glucagon Precursors)IBA 01/2016 - 11/2014
3	Metformin (Glucophage)FDA LinkGeneric 05/2015 - 06/2004
3	Protein Kinases (Protein Kinase)IBA 11/2014 - 06/2010
3	Protein Isoforms (Isoforms)IBA 02/2011 - 04/2005
2	AntioxidantsIBA 04/2024 - 04/2005
2	ProinsulinIBA 01/2023 - 10/2020
2	Blood Glucose (Blood Sugar)IBA 11/2022 - 01/2021
2	Sirtuin 3IBA 01/2022 - 01/2021
2	IncretinsIBA 07/2018 - 12/2015
2	Exenatide (Byetta)FDA Link 03/2018 - 01/2014
2	Adenosine Triphosphatases (ATPase)IBA 02/2015 - 01/2008
2	Pyruvic Acid (Pyruvate)IBA 07/2012 - 09/2007
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2006 - 04/2003
2	(L)-Isomer Glucose (L-Glucose)IBA 04/2006 - 04/2005
2	enhanced green fluorescent proteinIBA 04/2006 - 04/2003
1	dapagliflozinIBA 04/2024
1	CorticosteroneIBA 04/2024
1	Interleukin-6 (Interleukin 6)IBA 04/2024
1	Penfluridol (Semap)IBA 12/2023
1	Terfenadine (Seldane)IBA 12/2023
1	14-3-3 Proteins (14-3-3 Protein)IBA 12/2023
1	BMS201038IBA 12/2023
1	Ion Pumps (Ion Pump)IBA 01/2023
1	Immunoglobulin G (IgG)IBA 01/2023
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2023
1	AutoantibodiesIBA 01/2023
1	AutoantigensIBA 01/2023
1	Biomarkers (Surrogate Marker)IBA 01/2023
1	semaglutideIBA 11/2022
1	N,N,N',N'- tetrakis(2- pyridylmethyl)ethylenediamineIBA 11/2022
1	GTP-Binding Proteins (G-Protein)IBA 11/2022
1	CystathionineIBA 01/2022
1	HomocysteineIBA 01/2022
1	salicylhydroxamic acid (SHAM)IBA 01/2022
1	Cystathionine beta-Synthase (Serine Sulfhydrase)IBA 01/2022
1	Serotonin (5 Hydroxytryptamine)IBA 01/2021
1	CateninsIBA 01/2021
1	ArrestinsIBA 01/2021
1	HDL CholesterolIBA 01/2021
1	ChromatinIBA 01/2021
1	Sucrose (Saccharose)IBA 01/2021
1	LigandsIBA 11/2020
1	Carrier Proteins (Binding Protein)IBA 10/2020
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2020
1	Polysaccharides (Glycans)IBA 01/2020

Therapy/Procedure

8	Therapeutics 01/2023 - 09/2015
5	Bariatric Surgery 12/2022 - 01/2020