Clemens Ruppert Selected Research

Hyperplasia

12/2019	WNT/RYK signaling restricts goblet cell differentiation during lung development and repair.
11/2014	Altered surfactant homeostasis and alveolar epithelial cell stress in amiodarone-induced lung fibrosis.

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Clemens Ruppert Research Topics

Disease

20	Fibrosis (Cirrhosis) 04/2024 - 12/2003
17	Idiopathic Pulmonary Fibrosis 04/2024 - 02/2009
10	Pulmonary Fibrosis (Fibrosing Alveolitis) 10/2023 - 12/2003
9	Lung Injury 05/2024 - 01/2006
9	Interstitial Lung Diseases (Interstitial Lung Disease) 10/2023 - 07/2002
7	Pulmonary Arterial Hypertension 05/2024 - 01/2019
7	Vascular Remodeling 04/2024 - 01/2018
7	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 07/2010 - 12/2003
6	Neoplasms (Cancer) 04/2024 - 03/2004
6	Chronic Obstructive Pulmonary Disease (COPD) 01/2022 - 10/2008
5	Hypoxia (Hypoxemia) 04/2024 - 01/2019
5	Pneumonia (Pneumonitis) 01/2022 - 03/2004
5	Acute Lung Injury 01/2017 - 07/2007
4	Lung Neoplasms (Lung Cancer) 01/2023 - 08/2005
4	Lung Diseases (Lung Disease) 01/2022 - 09/2004
3	Pulmonary Hypertension 04/2024 - 01/2022
3	Sarcoidosis (Schaumann Disease) 12/2021 - 02/2009
2	COVID-19 01/2022 - 01/2021
2	Hyperplasia 12/2019 - 11/2014
2	Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis) 05/2019 - 02/2009
2	Body Weight (Weight, Body) 12/2018 - 12/2003
2	Surfactant Dysfunction 01/2017 - 07/2015
2	Lewis Lung Carcinoma 11/2012 - 03/2010
1	Familial Primary Pulmonary Hypertension 05/2024
1	Necrosis 04/2024
1	Glioma (Gliomas) 04/2024
1	Heart Diseases (Heart Disease) 01/2022
1	Infections 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Right Ventricular Hypertrophy 01/2021
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Ulcerative Colitis 01/2019

Drug/Important Bio-Agent (IBA)

14	Bleomycin (Blenoxane)FDA LinkGeneric 05/2024 - 12/2003
14	Surface-Active Agents (Surfactants)IBA 01/2023 - 03/2004
9	Proteins (Proteins, Gene)FDA Link 04/2024 - 10/2005
7	FibrinIBA 06/2010 - 07/2002
6	CollagenIBA 10/2023 - 12/2003
6	Pulmonary Surfactants (Pulmonary Surfactant)IBA 06/2011 - 03/2004
5	indium-bleomycinIBA 10/2023 - 03/2004
5	Transcription Factors (Transcription Factor)IBA 01/2023 - 10/2008
4	RNA (Ribonucleic Acid)IBA 04/2024 - 04/2007
4	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 06/2010 - 12/2003
3	AntibodiesIBA 10/2023 - 06/2010
3	Amiodarone (Amiodarona)FDA LinkGeneric 10/2015 - 11/2014
3	Hydroxyproline (4 Hydroxyproline)IBA 11/2014 - 12/2003
3	Protein CIBA 04/2011 - 01/2006
2	Insulin-Like Growth Factor Binding ProteinsIBA 05/2024 - 01/2022
2	DisulfidesIBA 12/2023 - 01/2019
2	ChromatinIBA 01/2023 - 01/2022
2	Long Noncoding RNAIBA 01/2023 - 01/2022
2	Semaxinib (SU5416)IBA 01/2022 - 01/2019
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022 - 11/2012
2	ProteomeIBA 01/2022 - 06/2013
2	AerosolsIBA 07/2010 - 12/2003
2	Heparin (Liquaemin)FDA LinkGeneric 06/2010 - 12/2003
1	Insulin-Like Growth Factor Binding Protein 3IBA 05/2024
1	Insulin-Like Growth Factor Binding Protein 2IBA 05/2024
1	Insulin-Like Growth Factor Binding Protein 1IBA 05/2024
1	nintedanibIBA 04/2024
1	Peptides (Polypeptides)IBA 04/2024
1	caveolin-1 (82-101)IBA 04/2024
1	SmokeIBA 04/2024
1	Auranofin (Ridaura)FDA Link 12/2023
1	CyclinsIBA 12/2023
1	Histones (Histone)IBA 10/2023
1	Neutralizing AntibodiesIBA 10/2023
1	Interleukin-27 (Interleukin 27)IBA 10/2023
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2023
1	CytokinesIBA 01/2023
1	Janus KinasesIBA 01/2023
1	Red DND-99IBA 11/2022
1	LectinsIBA 01/2022
1	AlarminsIBA 01/2022
1	Insulin-Like PeptidesIBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Tamoxifen FDA LinkGeneric 01/2022
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 01/2022
1	Tacrolimus Binding Proteins (FKBP)IBA 01/2022
1	jugloneIBA 01/2022
1	CREB-Binding ProteinIBA 01/2022
1	CateninsIBA 01/2022
1	CD40 Ligand (CD40L)IBA 12/2021
1	interleukin-21 (interleukin 21)IBA 12/2021
1	Angiotensin Receptor AntagonistsIBA 01/2021
1	ruxolitinibIBA 01/2021
1	Ethylnitrosourea (N-Ethyl-N-nitrosourea)IBA 12/2019
1	Bone Morphogenetic Protein ReceptorsIBA 12/2019
1	Cathepsin AIBA 11/2019
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 11/2019
1	Autophagy-Related ProteinsIBA 11/2019
1	EicosanoidsIBA 05/2019
1	Dinoprostone (PGE2)FDA Link 05/2019
1	EnzymesIBA 05/2019
1	ImmunosorbentsIBA 05/2019
1	8-epi-prostaglandin F2alphaIBA 05/2019
1	IsoprostanesIBA 05/2019
1	Biomarkers (Surrogate Marker)IBA 05/2019
1	palbociclibIBA 01/2019

Therapy/Procedure

6	Therapeutics 01/2021 - 08/2005
4	Artificial Respiration (Mechanical Ventilation) 05/2024 - 07/2007