Bruce J Roth Selected Research

Vascular Endothelial Growth Factor Receptors (VEGF Receptors)

10/2021	Vorolanib (X-82), an oral anti-VEGFR/PDGFR/CSF1R tyrosine kinase inhibitor, with everolimus in solid tumors: results of a phase I study.
11/2015	Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma.

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Bruce J Roth Research Topics

Disease

14	Neoplasms (Cancer) 10/2021 - 01/2004
10	Prostatic Neoplasms (Prostate Cancer) 01/2023 - 05/2005
9	Carcinoma (Carcinomatosis) 02/2019 - 07/2002
4	Renal Cell Carcinoma (Grawitz Tumor) 10/2021 - 11/2015
3	Disease Progression 07/2016 - 06/2003
2	Urinary Bladder Neoplasms (Bladder Cancer) 01/2021 - 01/2019
2	Fatigue 07/2016 - 09/2009
2	Testicular Neoplasms (Testicular Cancer) 01/2007 - 07/2002
2	Transitional Cell Carcinoma 07/2006 - 11/2002
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 02/2019
1	Nausea 10/2018
1	Diarrhea 10/2018
1	Dyspnea (Shortness of Breath) 10/2018
1	Neoplasm Metastasis (Metastasis) 10/2018
1	Aspiration Pneumonia 07/2016
1	Hypertension (High Blood Pressure) 07/2016
1	Aspergillosis 07/2016
1	Hand-Foot Syndrome 09/2009
1	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 01/2007
1	Adenocarcinoma 05/2006
1	Neutropenia 01/2004

Drug/Important Bio-Agent (IBA)

4	Everolimus FDA Link 10/2021 - 11/2015
4	Tyrosine Kinase InhibitorsIBA 10/2021 - 09/2009
3	AndrogensIBA 10/2022 - 05/2006
3	cabozantinibIBA 10/2018 - 11/2015
3	Paclitaxel (Taxol)FDA LinkGeneric 01/2018 - 04/2004
3	Docetaxel (Taxotere)FDA Link 08/2007 - 06/2003
2	Hormones (Hormone)IBA 10/2022 - 01/2018
2	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 10/2021 - 11/2015
2	Cisplatin (Platino)FDA LinkGeneric 09/2009 - 04/2004
2	Pemetrexed (MTA)FDA Link 06/2008 - 07/2006
2	Gemcitabine FDA Link 06/2008 - 06/2003
2	Methotrexate (Mexate)FDA LinkGeneric 04/2004 - 11/2002
1	enzalutamideIBA 01/2023
1	abirateroneIBA 01/2023
1	Prednisone (Sone)FDA LinkGeneric 01/2023
1	antiarrhythmic peptide (AAP)IBA 01/2023
1	Abiraterone AcetateIBA 01/2023
1	orteronelIBA 10/2022
1	bicalutamide (Casodex)FDA LinkGeneric 10/2022
1	vorolanibIBA 10/2021
1	MTOR InhibitorsIBA 10/2021
1	Estramustine FDA Link 01/2018
1	Prostate-Specific Antigen (Semenogelase)IBA 09/2012
1	Sorafenib (BAY 43-9006)FDA Link 09/2009
1	Epirubicin (Ellence)FDA LinkGeneric 10/2008
1	Irinotecan (Camptosar)FDA LinkGeneric 10/2008
1	Biomarkers (Surrogate Marker)IBA 07/2008
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 07/2008
1	Proteins (Proteins, Gene)FDA Link 07/2008
1	ixabepilone (BMS 247550)FDA Link 08/2007
1	epothilone B (EPO906)IBA 08/2007
1	E 3800IBA 08/2007
1	VA 061 (VA061)IBA 05/2006
1	Carboplatin (JM8)FDA LinkGeneric 04/2004
1	Vinblastine (Vinblastine Sulfate)FDA Link 04/2004
1	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2004
1	brostallicinIBA 01/2004
1	DNA (Deoxyribonucleic Acid)IBA 01/2004
1	piritreximIBA 11/2002

Therapy/Procedure

6	Therapeutics 10/2022 - 04/2004
6	Drug Therapy (Chemotherapy) 01/2019 - 05/2005
4	Castration 01/2023 - 08/2013
2	Radiotherapy 02/2019 - 01/2019
1	Chemoradiotherapy 01/2021
1	Treatment Delay 01/2021
1	Transurethral Resection of Bladder 01/2021
1	Cystectomy 01/2019
1	Prostatectomy (Retropubic Prostatectomy) 05/2007
1	Aftercare (After-Treatment) 01/2007
1	Salvage Therapy 01/2007
1	Lymph Node Excision (Lymph Node Dissection) 07/2002