Frits R Rosendaal Selected Research

Hemorrhage

12/2023	Genomic science of risk prediction for venous thromboembolic disease: convenient clarification or compounding complexity.
1/2022	Von Willebrand factor propeptide and pathophysiological mechanisms in European and Iranian patients with type 3 von Willebrand disease enrolled in the 3WINTERS-IPS study.
1/2022	Risk of drug-related upper gastrointestinal bleeding in the total population of the Netherlands: a time-trend analysis.
6/2021	Differential effect of statin use on coagulation markers: an active comparative analysis in the NEO study.
1/2020	Dosage reduction of low weight heparin in patients with renal dysfunction: Effects on anti-Xa levels and clinical outcomes.
10/2019	Prediction of recurrent venous thrombosis in all patients with a first venous thrombotic event: The Leiden Thrombosis Recurrence Risk Prediction model (L-TRRiP).
1/2019	Rosuvastatin use reduces thrombin generation potential in patients with venous thromboembolism: a randomized controlled trial.
11/2016	Can we prevent venous thrombosis with statins: an epidemiologic review into mechanism and clinical utility.
1/2016	Statins and Risk of Bleeding: An Analysis to Evaluate Possible Bias Due to Prevalent Users and Healthy User Aspects.
2/2014	Suspected survivor bias in case-control studies: stratify on survival time and use a negative control.

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Frits R Rosendaal Research Topics

Disease

105	Venous Thrombosis (Deep-Vein Thrombosis) 03/2024 - 01/2002
61	Thrombosis (Thrombus) 12/2020 - 01/2002
37	Obesity 03/2024 - 03/2003
30	Myocardial Infarction 11/2019 - 02/2002
25	Hemorrhage 12/2023 - 04/2002
25	Thrombophilia 05/2021 - 01/2002
24	Venous Thromboembolism 03/2024 - 01/2001
16	Neoplasms (Cancer) 07/2023 - 02/2004
16	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 04/2002
13	Ischemic Stroke 08/2023 - 02/2002
10	COVID-19 03/2024 - 01/2020
10	Inflammation (Inflammations) 10/2023 - 01/2002
9	Hypertension (High Blood Pressure) 04/2024 - 04/2002
9	Hemophilia A (Haemophilia) 01/2024 - 12/2004
9	Infections 07/2023 - 10/2002
9	Pain (Aches) 01/2023 - 11/2003
8	Atrial Fibrillation 01/2021 - 11/2003
7	Osteoarthritis 01/2023 - 05/2005
7	Insulin Resistance 01/2023 - 01/2019
7	Stroke (Strokes) 12/2020 - 04/2002
6	Pulmonary Embolism 03/2014 - 04/2006
6	Activated Protein C Resistance (APC Resistance) 04/2009 - 03/2002
5	Coronary Artery Disease (Coronary Atherosclerosis) 01/2023 - 01/2018
5	Type 2 Diabetes Mellitus (MODY) 01/2023 - 01/2016
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 07/2009
5	Overweight 05/2016 - 10/2004
4	Coronary Disease (Coronary Heart Disease) 08/2023 - 11/2008
4	Atherosclerosis 01/2023 - 07/2009
4	Wounds and Injuries (Trauma) 08/2015 - 07/2006
4	Thromboembolism 07/2009 - 11/2003
4	Hyperhomocysteinemia 01/2007 - 10/2002
3	Genetic Risk Score 06/2023 - 10/2017
3	Synovitis 01/2022 - 11/2019
3	Hepatitis C 01/2021 - 12/2004

Drug/Important Bio-Agent (IBA)

27	factor V LeidenIBA 01/2023 - 01/2002
25	Oral ContraceptivesIBA 12/2020 - 05/2002
23	Factor VIII (Coagulation Factor VIII)IBA 07/2023 - 01/2002
22	AnticoagulantsIBA 12/2023 - 04/2002
19	Blood Coagulation Factors (Coagulation Factor)IBA 02/2024 - 03/2003
16	Glucose (Dextrose)FDA LinkGeneric 02/2023 - 01/2006
16	Hormones (Hormone)IBA 01/2021 - 10/2004
15	Triglycerides (Triacylglycerol)IBA 01/2023 - 10/2004
15	Protein CIBA 01/2023 - 06/2003
13	Thrombin FDA Link 02/2024 - 03/2002
13	Prothrombin (Factor II)IBA 01/2023 - 01/2002
13	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 06/2021 - 01/2001
12	von Willebrand FactorIBA 07/2023 - 03/2007
10	LipidsIBA 06/2021 - 10/2004
10	Estrogens (Estrogen)FDA Link 04/2009 - 02/2003
9	Combined Oral ContraceptivesIBA 03/2024 - 02/2003
9	C-Reactive ProteinIBA 01/2023 - 01/2002
9	Insulin (Novolin)FDA Link 11/2021 - 01/2006
9	AntigensIBA 01/2021 - 10/2002
9	HomocysteineIBA 10/2019 - 01/2002
9	Tyr sulfate(1)- enkephalinamide-Leu (LETS)IBA 08/2012 - 01/2002
8	Progestins (Progestagens)IBA 03/2024 - 05/2002
8	Proteins (Proteins, Gene)FDA Link 01/2023 - 02/2007
8	Biomarkers (Surrogate Marker)IBA 05/2021 - 03/2005
8	Factor XIII (Coagulation Factor XIII)IBA 05/2011 - 02/2002
7	Fibrinogen (Factor I)FDA Link 06/2023 - 03/2003
7	Blood Group Antigens (Blood Groups)IBA 01/2023 - 04/2010
7	Opioid Analgesics (Opioids)IBA 01/2023 - 01/2019
7	Levonorgestrel (Plan B)FDA LinkGeneric 10/2020 - 05/2002
6	LeptinIBA 04/2024 - 01/2018
6	AntithrombinsIBA 01/2023 - 06/2003
6	Protein SIBA 01/2023 - 11/2002
5	AdiponectinIBA 04/2024 - 01/2018
5	Contraceptive Agents (Contraceptives)IBA 03/2024 - 02/2003
5	AntibodiesIBA 01/2024 - 12/2004
5	ORALIT (ORS)IBA 01/2023 - 05/2011
5	Hemostatics (Antihemorrhagics)IBA 01/2019 - 01/2002
5	Vitamin K FDA Link 06/2017 - 10/2005
4	VaccinesIBA 06/2023 - 10/2019
4	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2023 - 01/2013
4	oxidized low density lipoproteinIBA 01/2023 - 01/2019
4	Lipoproteins (Lipoprotein)IBA 01/2022 - 01/2019
4	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2022 - 11/2019
4	fibrin fragment D (D-dimer)IBA 07/2021 - 01/2002
4	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 03/2007
4	lipoprotein-associated coagulation inhibitor (TFPI)IBA 04/2018 - 02/2006
4	Factor V (Coagulation Factor V)IBA 04/2018 - 10/2004
4	HDL CholesterolIBA 01/2018 - 10/2004
4	CholesterolIBA 01/2016 - 10/2004
4	Desogestrel FDA LinkGeneric 03/2014 - 05/2002
4	GestodeneIBA 03/2014 - 05/2002
4	Tissue Plasminogen Activator (Alteplase)FDA Link 07/2010 - 05/2007
4	PlasminogenIBA 07/2010 - 05/2007
4	Carboxypeptidase B2 (Thrombin Activatable Fibrinolysis Inhibitor)IBA 07/2009 - 02/2007
3	Neutralizing AntibodiesIBA 01/2024 - 05/2016
3	remdesivirIBA 10/2023 - 01/2021
3	Dexamethasone (Maxidex)FDA LinkGeneric 10/2023 - 01/2022
3	InterleukinsIBA 04/2023 - 03/2005
3	Prednisolone (Predate)FDA LinkGeneric 01/2022 - 11/2019
3	CreatinineIBA 11/2021 - 01/2020
3	NucleotidesIBA 01/2021 - 01/2016
3	Messenger RNA (mRNA)IBA 01/2021 - 03/2005

Therapy/Procedure

31	Therapeutics 01/2023 - 04/2002
4	Hormone Replacement Therapy (Therapy, Hormone Replacement) 01/2015 - 06/2002
4	Central Venous Catheters 01/2008 - 11/2003
3	Arthroplasty 01/2023 - 01/2022