David Roife Selected Research

Irinotecan (Camptosar)

1/2022	CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop.
11/2020	CES2 Expression in Pancreatic Adenocarcinoma Is Predictive of Response to Irinotecan and Is Associated With Type 2 Diabetes.

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David Roife Research Topics

Disease

12	Neoplasms (Cancer) 01/2022 - 09/2014
6	Adenocarcinoma 01/2022 - 12/2014
6	Pancreatic Neoplasms (Pancreatic Cancer) 10/2021 - 09/2014
2	Fibrosis (Cirrhosis) 04/2020 - 09/2007
2	Hepatocellular Carcinoma (Hepatoma) 04/2020 - 01/2020
2	Wounds and Injuries (Trauma) 01/2020 - 05/2009
2	Hiatal Hernia 10/2017 - 08/2017
1	Mesothelioma 12/2020
1	Type 2 Diabetes Mellitus (MODY) 11/2020
1	End Stage Liver Disease 04/2020
1	Carcinogenesis 01/2020
1	Neoplasm Metastasis (Metastasis) 01/2020
1	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020
1	Ovarian Neoplasms (Ovarian Cancer) 10/2019
1	Ileus 10/2017
1	Thrombocytopenia (Thrombopenia) 10/2017
1	Atrial Fibrillation 10/2017
1	Brain Neoplasms (Brain Tumor) 01/2017
1	Cicatrix (Scar) 08/2015
1	Breast Neoplasms (Breast Cancer) 08/2015
1	Hypoxia (Hypoxemia) 12/2014
1	Disease Progression 12/2014
1	B-Cell Lymphoma (Lymphoma, B Cell) 09/2014
1	Inflammation (Inflammations) 01/2013
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 09/2007
1	Asthma (Bronchial Asthma) 09/2007

Drug/Important Bio-Agent (IBA)

4	CollagenIBA 10/2016 - 09/2007
3	Proteins (Proteins, Gene)FDA Link 11/2020 - 01/2017
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2022 - 11/2020
2	Fluorouracil (Carac)FDA LinkGeneric 11/2020 - 09/2014
2	folfirinoxIBA 11/2020 - 09/2014
2	CytokinesIBA 01/2020 - 05/2009
2	LumicanIBA 10/2016 - 12/2014
2	Amyloid (Amyloid Fibrils)IBA 05/2009 - 09/2007
1	Carboxylesterase (Hydrolase S)IBA 01/2022
1	Epoxide HydrolasesIBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	ProdrugsIBA 01/2022
1	HydrolasesIBA 01/2022
1	AsparagineIBA 10/2021
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2020
1	Leucovorin (Folinic Acid)FDA Link 11/2020
1	BilirubinIBA 04/2020
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 04/2020
1	CreatinineIBA 04/2020
1	A-factor (Streptomyces)IBA 01/2020
1	Antineoplastic Agents (Antineoplastics)IBA 10/2019
1	Antirheumatic Agents (DMARD)IBA 10/2019
1	Auranofin (Ridaura)FDA Link 10/2019
1	Heparin (Liquaemin)FDA LinkGeneric 10/2017
1	PhosphatidylserinesIBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 10/2016
1	Hormones (Hormone)IBA 01/2016
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2016
1	Estrogen ReceptorsIBA 01/2016
1	Carrier Proteins (Binding Protein)IBA 08/2015
1	Galectin 3 (LGALS3)IBA 08/2015
1	Lactic Acid (Lactate)FDA LinkGeneric 12/2014
1	Adenosine Triphosphate (ATP)IBA 12/2014
1	Glucose (Dextrose)FDA LinkGeneric 12/2014
1	GenisteinIBA 09/2014
1	Cytotoxins (Cytolysins)IBA 09/2014
1	Beclin-1IBA 09/2014
1	Extracellular Matrix ProteinsIBA 01/2013
1	Sepharose (Agarose)IBA 05/2009
1	HydrogelsIBA 05/2009
1	Bleomycin (Blenoxane)FDA LinkGeneric 09/2007
1	Hemoglobins (Hemoglobin)IBA 09/2007

Therapy/Procedure

7	Therapeutics 10/2021 - 09/2007
1	Hyperthermic Intraperitoneal Chemotherapy 12/2020
1	Combination Drug Therapy (Combination Chemotherapy) 11/2020
1	Drug Therapy (Chemotherapy) 01/2020
1	Perioperative Period 10/2017
1	Length of Stay 08/2017
1	Heterologous Transplantation (Xenotransplantation) 01/2017
1	Transcutaneous Electric Nerve Stimulation (TENS) 09/2007
1	Treatment Delay 09/2007
1	Injections 09/2007