Christine Roffe Selected Research

Thrombolytic Therapy

1/2019	The association between early neurological deterioration and whole blood purine concentration during acute stroke.
6/2016	Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke.

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Christine Roffe Research Topics

Disease

52	Stroke (Strokes) 12/2023 - 11/2003
13	Ischemic Stroke 09/2023 - 03/2010
8	Hypoxia (Hypoxemia) 01/2019 - 01/2010
6	Cerebral Hemorrhage 06/2021 - 01/2016
6	Pneumonia (Pneumonitis) 06/2021 - 02/2015
3	Hemorrhage 10/2023 - 01/2018
3	Thrombosis (Thrombus) 09/2016 - 03/2010
2	Brain Edema (Cerebral Edema) 12/2023 - 01/2023
2	Urinary Tract Infections (Urinary Tract Infection) 01/2022 - 01/2021
2	Hematoma 01/2021 - 01/2020
2	Hypertension (High Blood Pressure) 02/2019 - 01/2018
2	Wounds and Injuries (Trauma) 01/2019 - 01/2018
2	Deglutition Disorders (Dysphagia) 01/2018 - 01/2016
1	MELAS Syndrome (Syndrome, MELAS) 02/2024
1	Lower Urinary Tract Symptoms 12/2023
1	Infarction (Infarctions) 12/2023
1	Lacunar Stroke 01/2023
1	Cerebral Small Vessel Diseases 01/2023
1	Cognitive Dysfunction 01/2023
1	Conversion Disorder (Astasia Abasia) 01/2022
1	Urinary Incontinence 01/2022
1	Thrombocytopenia (Thrombopenia) 01/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2021
1	COVID-19 01/2021
1	Hyperglycemia 01/2019
1	Body Weight (Weight, Body) 06/2016
1	Aspiration Pneumonia 01/2016
1	Malnutrition (Nutritional Deficiencies) 01/2016
1	Respiratory Tract Infections (Respiratory Tract Infection) 08/2015
1	Heart Failure 09/2014
1	Renal Insufficiency (Renal Failure) 09/2014
1	Infections 03/2014
1	Charles Bonnet Syndrome 11/2010
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2010
1	Psychomotor Agitation (Akathisia) 01/2010
1	Muscle Cramp (Cramp) 05/2002
1	Sleep-Wake Transition Disorders (Sleep Talking) 05/2002

Drug/Important Bio-Agent (IBA)

15	Oxygen (Dioxygen)IBA 01/2021 - 11/2003
5	Nitroglycerin (Dynamite)FDA LinkGeneric 06/2023 - 01/2018
5	Anti-Bacterial Agents (Antibiotics)IBA 06/2021 - 08/2015
5	Tranexamic Acid (AMCA)FDA Link 01/2021 - 01/2016
4	salicylhydroxamic acid (SHAM)IBA 06/2023 - 11/2019
4	Tissue Plasminogen Activator (Alteplase)FDA Link 02/2019 - 03/2010
3	4- Acetamido- 4'- isothiocyanatostilbene- 2,2'- disulfonic Acid (SITS)IBA 12/2023 - 01/2019
3	PurinesIBA 05/2021 - 01/2019
3	Biomarkers (Surrogate Marker)IBA 12/2019 - 08/2015
2	purineIBA 05/2021 - 01/2019
2	fibrin fragment D (D-dimer)IBA 01/2021 - 01/2021
2	Adenosine Triphosphate (ATP)IBA 01/2019 - 01/2019
2	C-Reactive ProteinIBA 01/2016 - 08/2015
2	Botulinum Toxins (Botulinum Toxin)IBA 06/2010 - 07/2009
1	Lactic Acid (Lactate)FDA LinkGeneric 02/2024
1	Indicators and Reagents (Reagents)IBA 12/2023
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 10/2023
1	CholesterolIBA 01/2023
1	isosorbide-5-mononitrate (Ismo)FDA LinkGeneric 01/2023
1	Cilostazol (Pletal)FDA LinkGeneric 01/2023
1	VaccinesIBA 01/2021
1	Immunoglobulins (Immunoglobulin)IBA 01/2021
1	Platelet Factor 4IBA 01/2021
1	AntibodiesIBA 01/2021
1	Heparin (Liquaemin)FDA LinkGeneric 01/2021
1	AnticoagulantsIBA 01/2021
1	Vasodilator Agents (Vasodilators)IBA 11/2019
1	Adenosine (Adenocard)FDA LinkGeneric 01/2019
1	Inosine FDA Link 01/2019
1	HypoxanthineIBA 01/2019
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018
1	ElementsIBA 01/2016
1	ProcalcitoninIBA 08/2015
1	2,6-dinitrotoluene (DNT)IBA 05/2015
1	AntiemeticsIBA 02/2015
1	Metoclopramide (Reglan)FDA LinkGeneric 02/2015
1	DiureticsIBA 09/2014
1	Glutamic Acid (Glutamate)FDA Link 09/2014
1	Free RadicalsIBA 03/2014
1	N 30IBA 01/2011
1	Ringer's LactateIBA 01/2011
1	MagnesiumIBA 05/2002
1	magnesium citrateIBA 05/2002
1	SaltsIBA 05/2002

Therapy/Procedure

12	Therapeutics 03/2023 - 10/2012
11	Thrombectomy 12/2023 - 03/2010
3	Contraindications 01/2023 - 01/2017
3	Catheters 09/2016 - 03/2010
2	Thrombolytic Therapy 01/2019 - 06/2016
2	Stroke Rehabilitation 10/2012 - 03/2010
1	Activities of Daily Living (ADL) 12/2023
1	Urinary Catheters 01/2022
1	Hypnosis (Mesmerism) 01/2022
1	Stents 09/2016
1	Institutionalization (Institutionalized Persons) 01/2016
1	Secondary Prevention 01/2016
1	Percutaneous Coronary Intervention 01/2016
1	Early Ambulation 03/2014
1	Cannula 01/2010