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Victoria M Richon Selected Research

Non-Hodgkin Lymphoma (Lymphosarcoma)

4/2014Selective inhibition of EZH2 by EPZ-6438 leads to potent antitumor activity in EZH2-mutant non-Hodgkin lymphoma.
10/2011The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states.

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Victoria M Richon Research Topics

Disease

31Neoplasms (Cancer)
01/2021 - 03/2002
7Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
05/2015 - 01/2007
7Leukemia
05/2014 - 08/2006
3Lymphoma (Lymphomas)
02/2016 - 05/2008
3Multiple Myeloma
07/2009 - 05/2003
2Breast Neoplasms (Breast Cancer)
07/2015 - 10/2009
2Non-Hodgkin Lymphoma (Lymphosarcoma)
04/2014 - 10/2011
2Weight Loss (Weight Reduction)
08/2013 - 01/2010
2Hematologic Neoplasms (Hematological Malignancy)
03/2013 - 07/2009
2Myelodysplastic Syndromes (Myelodysplastic Syndrome)
07/2009 - 02/2008
2Glioblastoma (Glioblastoma Multiforme)
07/2009 - 04/2009
1T-Cell Lymphoma (Lymphoma, T Cell)
07/2015
1Rhabdoid Tumor (Rhabdoid Tumors)
05/2013
1Rare Diseases (Rare Disease)
01/2013
1B-Cell Lymphoma (Lymphoma, B Cell)
12/2010
1Brain Neoplasms (Brain Tumor)
10/2009
1Triple Negative Breast Neoplasms
10/2009
1Neoplasm Micrometastasis
10/2009
1Neoplasm Metastasis (Metastasis)
10/2009
1Anorexia
07/2009
1Diarrhea
07/2009
1Vomiting
07/2009
1Fatigue
07/2009
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
07/2009
1Nausea
07/2009
1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
04/2009
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
04/2009
1Colonic Neoplasms (Colon Cancer)
09/2008
1Mycosis Fungoides
05/2008
1Prostatic Neoplasms (Prostate Cancer)
01/2007
1Pruritus (Itching)
01/2007
1Melanoma (Melanoma, Malignant)
08/2006
1Retinoblastoma (Glioblastoma, Retinal)
05/2005
1Thyroid Neoplasms (Thyroid Cancer)
05/2005
1Medullary Carcinoma
05/2005
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
09/2004
1Rhabdomyosarcoma
11/2003
1Thrombocytopenia (Thrombopenia)
09/2003
1Leukopenia
09/2003
1Huntington Disease (Huntington's Disease)
02/2003
1Nervous System Diseases (Neurological Disorders)
02/2003

Drug/Important Bio-Agent (IBA)

25Histone Deacetylase InhibitorsIBA
07/2015 - 03/2002
24VorinostatFDA Link
07/2015 - 05/2002
12Histones (Histone)IBA
02/2016 - 09/2003
7Lysine (L-Lysine)FDA Link
02/2016 - 12/2003
5Histone Deacetylases (Histone Deacetylase)IBA
06/2010 - 09/2002
3Histone MethyltransferasesIBA
05/2014 - 08/2013
3ChromatinIBA
03/2013 - 08/2006
3Proteins (Proteins, Gene)FDA Link
05/2005 - 05/2003
2tazemetostatIBA
02/2016 - 04/2014
2EPZ-5676IBA
05/2014 - 08/2013
2MethyltransferasesIBA
05/2013 - 07/2011
2EnzymesIBA
09/2008 - 12/2003
1Messenger RNA (mRNA)IBA
01/2021
1Nucleic AcidsIBA
01/2021
1Immune Checkpoint InhibitorsIBA
01/2021
1Interferon Type IIBA
01/2021
1Buthionine SulfoximineIBA
07/2015
1Glutathione (Reduced Glutathione)IBA
07/2015
1AntioxidantsIBA
07/2015
1A-factor (Streptomyces)IBA
07/2015
1Puromycin AminonucleosideIBA
05/2014
1tetrahydrofuranIBA
05/2014
1Sucrose (Saccharose)IBA
05/2013
1diphenyl (biphenyl)IBA
05/2013
1PyransIBA
05/2013
1Oncogene Proteins (Oncogene Protein)IBA
03/2013
1Tyrosine (L-Tyrosine)FDA Link
10/2011
1histone H3 trimethyl Lys4IBA
07/2011
1DNA (Deoxyribonucleic Acid)IBA
10/2009
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
04/2009
1Gamma Secretase Inhibitors and ModulatorsIBA
04/2009
1Notch ReceptorsIBA
04/2009
1Fatty Acids (Saturated Fatty Acids)IBA
09/2008
1Androgen Receptors (Androgen Receptor)IBA
01/2007
1AndrogensIBA
01/2007
1Androgen Receptor AntagonistsIBA
01/2007
1thiamine triphosphorate (TTP)IBA
01/2007
1AnthracyclinesIBA
08/2006
1Caspase 8 (Caspase-8)IBA
05/2005
1AcidsIBA
05/2005
1CaspasesIBA
05/2005
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2005
1Complementary DNA (cDNA)IBA
05/2005
1Death Domain ReceptorsIBA
05/2005
1pyroxamideIBA
11/2003
1Hydroxamic Acids (Hydroxamic Acid)IBA
05/2003
1polyglutamineIBA
02/2003
1ThioredoxinsIBA
09/2002
1human TXNIP proteinIBA
09/2002
1Methylnitrosourea (N-Methyl-N-nitrosourea)IBA
05/2002
1CarcinogensIBA
05/2002

Therapy/Procedure

10Therapeutics
01/2021 - 02/2003
3Drug Therapy (Chemotherapy)
10/2009 - 05/2005