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Derek J Richard Selected Research

DNA-Binding Proteins (DNA Binding Protein)

11/2023An Exploration of Small Molecules That Bind Human Single-Stranded DNA Binding Protein 1.
12/2016Novel insight into the composition of human single-stranded DNA-binding protein 1 (hSSB1)-containing protein complexes.
4/2013Human single-stranded DNA binding proteins are essential for maintaining genomic stability.
8/2009HSSB1 and hSSB2 form similar multiprotein complexes that participate in DNA damage response.
5/2008Single-stranded DNA-binding protein hSSB1 is critical for genomic stability.

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Derek J Richard Research Topics

Disease

30Neoplasms (Cancer)
01/2024 - 10/2009
20Genomic Instability
11/2023 - 05/2008
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2021 - 02/2015
7Lung Neoplasms (Lung Cancer)
12/2023 - 08/2011
6Ataxia Telangiectasia (Louis Bar Syndrome)
01/2023 - 05/2008
4Breast Neoplasms (Breast Cancer)
01/2024 - 01/2012
4Triple Negative Breast Neoplasms
01/2024 - 06/2021
3Prostatic Neoplasms (Prostate Cancer)
01/2023 - 01/2015
3Progeria (Hutchinson Gilford Syndrome)
01/2021 - 12/2014
3Carcinogenesis
01/2016 - 04/2012
2Adenocarcinoma
09/2021 - 10/2020
2Chromosomal Instability (Chromosome Stability)
04/2010 - 08/2009
2Hypersensitivity (Allergy)
04/2010 - 08/2009
1Colorectal Neoplasms (Colorectal Cancer)
01/2024
1Eclampsia
02/2023
1Pre-Eclampsia (Preeclampsia)
02/2023
1Cicatrix (Scar)
01/2023
1Xeroderma Pigmentosum (Kaposi's Disease)
10/2021
1Urinary Bladder Neoplasms (Bladder Cancer)
06/2021
1Carcinoma (Carcinomatosis)
06/2021
1Premature Aging
01/2021
1Pathologic Processes
07/2020
1Ovarian Neoplasms (Ovarian Cancer)
01/2020
1Disease Progression
01/2018
1Hypoxia (Hypoxemia)
01/2016
1Chromosome Aberrations (Chromosome Abnormalities)
06/2014
1Genetic Translocation (Chromosomal Translocation)
01/2014

Drug/Important Bio-Agent (IBA)

27Proteins (Proteins, Gene)FDA Link
01/2024 - 10/2009
18DNA (Deoxyribonucleic Acid)IBA
09/2023 - 05/2008
5Phosphotransferases (Kinase)IBA
11/2023 - 05/2008
5DNA-Binding Proteins (DNA Binding Protein)IBA
11/2023 - 05/2008
5Biomarkers (Surrogate Marker)IBA
02/2022 - 06/2012
5PlatinumIBA
09/2021 - 12/2014
41,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
01/2023 - 04/2010
4Cisplatin (Platino)FDA LinkGeneric
01/2021 - 12/2014
3ErbB Receptors (EGF Receptor)IBA
11/2023 - 09/2020
3AndrogensIBA
01/2023 - 01/2015
3ChromatinIBA
01/2021 - 08/2012
3Indicators and Reagents (Reagents)IBA
10/2020 - 08/2009
3Messenger RNA (mRNA)IBA
10/2020 - 08/2011
2Small Interfering RNA (siRNA)IBA
01/2024 - 11/2016
2Hormones (Hormone)IBA
01/2024 - 01/2015
2Androgen Receptors (Androgen Receptor)IBA
01/2023 - 01/2015
2A-Form DNA (A-DNA)IBA
09/2021 - 06/2021
2chloropyramineIBA
10/2020 - 11/2016
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020 - 02/2015
2Neuropilin-1IBA
01/2020 - 02/2015
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2020 - 02/2015
2Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2020 - 10/2009
2Tumor Biomarkers (Tumor Markers)IBA
01/2018 - 01/2014
1Aurora Kinase BIBA
01/2024
1Fluorouracil (Carac)FDA LinkGeneric
01/2024
1emerinIBA
01/2024
13,3,5,5-tetramethyl-1-pyrroline N-oxide (TMPO)IBA
01/2024
1AntibodiesIBA
11/2023
1tyrosine receptor (receptor, tyrosine)IBA
11/2023
1Epidermal Growth Factor (EGF)IBA
11/2023
1OligonucleotidesIBA
11/2023
1OligosaccharidesIBA
11/2023
1Single-Stranded DNA (DNA, Single Stranded)IBA
11/2023
1EndoglinIBA
02/2023
1Thyroid Hormone-Binding ProteinsIBA
02/2023
1Prealbumin (Transthyretin)IBA
02/2023
1DNA-Activated Protein KinaseIBA
01/2023
1Glucose (Dextrose)FDA LinkGeneric
01/2023
1Transcription Factors (Transcription Factor)IBA
01/2023
1Tyrosine Kinase InhibitorsIBA
09/2021
1Phenobarbital (Luminal)FDA Link
06/2021
1Polynucleotide 5'-Hydroxyl-Kinase (Kinase, Polynucleotide)IBA
06/2021
1MethyltransferasesIBA
01/2021
1Cytotoxins (Cytolysins)IBA
01/2021
1Carboplatin (JM8)FDA LinkGeneric
01/2021
1lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA
01/2021
1Histone Deacetylases (Histone Deacetylase)IBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2020
1LipidsIBA
01/2018
1Nucleic AcidsIBA
01/2018
1MicroRNAs (MicroRNA)IBA
01/2018
1Histone Deacetylase InhibitorsIBA
01/2018
1CytokinesIBA
01/2016
1Oxygen (Dioxygen)IBA
01/2016
1SolutionsIBA
01/2016
1Testosterone (Sustanon)FDA Link
01/2016
1NucleophosminIBA
01/2016
1Sex Hormone-Binding GlobulinIBA
01/2016
1Bevacizumab (Avastin)FDA Link
02/2015
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2015
1Alanine (L-Alanine)FDA Link
12/2014
1Threonine (L-Threonine)FDA Link
12/2014
1CamptothecinIBA
06/2014
1Estrogens (Estrogen)FDA Link
05/2014
1Estrogen ReceptorsIBA
05/2014
1HeterochromatinIBA
08/2012
1Co-Repressor ProteinsIBA
08/2012

Therapy/Procedure

25Therapeutics
01/2024 - 10/2009
11Drug Therapy (Chemotherapy)
01/2024 - 10/2009
3Immunotherapy
01/2021 - 01/2020
1Radiotherapy
01/2023
1Subcutaneous Injections
02/2015
1Castration
01/2015