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Arghya Ray Selected Research

Bortezomib (Velcade)

8/2017Blockade of Deubiquitylating Enzyme USP1 Inhibits DNA Repair and Triggers Apoptosis in Multiple Myeloma Cells.
12/2015Synergistic anti-myeloma activity of the proteasome inhibitor marizomib and the IMiD immunomodulatory drug pomalidomide.
1/2014A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance.
6/2013In vitro and in vivo antitumor activity of a novel alkylating agent, melphalan-flufenamide, against multiple myeloma cells.

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Arghya Ray Research Topics

Disease

12Multiple Myeloma
01/2023 - 12/2011
6Neoplasms (Cancer)
01/2023 - 07/2007
5BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
05/2010 - 02/2005
4Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2011 - 07/2007
4Leukemia
12/2008 - 03/2007
2Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
05/2010 - 12/2006
1Fanconi Anemia (Fanconi's Anemia)
08/2017
1Peripheral Nervous System Diseases (PNS Diseases)
12/2015
1Mitochondrial Diseases (Mitochondrial Disease)
06/2013
1Ataxia Telangiectasia (Louis Bar Syndrome)
12/2011
1Hypereosinophilic Syndrome (Loeffler Endocarditis)
05/2010
1Disease Progression
07/2007
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
02/2005
1Philadelphia Chromosome
02/2005

Drug/Important Bio-Agent (IBA)

4UbiquitinIBA
01/2023 - 08/2017
4Bortezomib (Velcade)FDA Link
08/2017 - 06/2013
3Proteasome InhibitorsIBA
01/2023 - 01/2014
3Proteasome Endopeptidase Complex (Proteasome)IBA
01/2023 - 08/2017
3EnzymesIBA
08/2017 - 06/2013
3Imatinib Mesylate (Gleevec)FDA Link
05/2008 - 03/2007
2Phosphopyruvate Hydratase (Enolase)IBA
10/2021 - 01/2020
2Caspase 8 (Caspase-8)IBA
08/2017 - 12/2011
2Caspase 3 (Caspase-3)IBA
08/2017 - 12/2011
2Caspase 9IBA
08/2017 - 12/2011
2Proteins (Proteins, Gene)FDA Link
08/2017 - 07/2007
2Alkylating AgentsIBA
01/2016 - 06/2013
2Melphalan (Alkeran)FDA LinkGeneric
01/2016 - 06/2013
2melflufenIBA
01/2016 - 06/2013
2Reactive Oxygen Species (Oxygen Radicals)IBA
06/2013 - 12/2011
2Phosphotransferases (Kinase)IBA
01/2011 - 07/2007
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
09/2010 - 07/2007
2midostaurinIBA
12/2008 - 07/2007
2nilotinibFDA Link
05/2008 - 03/2007
1nucleotidaseIBA
01/2022
1Tryptophan (L-Tryptophan)FDA Link
01/2020
1KynurenineIBA
01/2020
1DNA-Binding Proteins (DNA Binding Protein)IBA
08/2017
1Small Interfering RNA (siRNA)IBA
06/2013
1DipeptidesIBA
06/2013
1Dexamethasone (Maxidex)FDA LinkGeneric
06/2013
1CaspasesIBA
06/2013
1CD13 Antigens (Alanine Aminopeptidase)IBA
06/2013
1ProdrugsIBA
06/2013
1Lenalidomide (CC 5013)FDA Link
06/2013
1Cytochromes c (Cytochrome c)IBA
06/2013
1Checkpoint Kinase 2IBA
12/2011
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
12/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2011
1SRT1720IBA
12/2011
1Sirtuin 1IBA
12/2011
1Platelet-Derived Growth Factor alpha ReceptorIBA
05/2010
1Adenosine Triphosphate (ATP)IBA
05/2010
1NVP-AST487IBA
12/2008
1Indicators and Reagents (Reagents)IBA
12/2008
1Protein Kinases (Protein Kinase)IBA
12/2008
1Tyrosine Kinase InhibitorsIBA
05/2008
1LBW242IBA
07/2007
1Drug CombinationsIBA
07/2007
1Tyrosine (L-Tyrosine)FDA Link
07/2007
1Proto-Oncogene Proteins c-kit (Proto-Oncogene Protein c-kit)IBA
12/2006
1Platelet-Derived Growth Factor Receptors (Platelet-Derived Growth Factor Receptor)IBA
12/2006
1bcr-abl Fusion ProteinsIBA
02/2005

Therapy/Procedure

5Therapeutics
08/2017 - 09/2010