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Vlad Ratziu Selected Research

Aspartate Aminotransferases (Aspartate Transaminase)

4/2024Impact of age on NIS2+™ and other non-invasive blood tests for the evaluation of liver disease and detection of at-risk MASH.
12/2023FibroScan-aspartate aminotransferase (FAST) score for monitoring histological improvement in non-alcoholic steatohepatitis activity during semaglutide treatment: post-hoc analysis of a randomised, double-blind, placebo-controlled, phase 2b trial.
12/2020Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis.
1/2020Development and Validation of Hepamet Fibrosis Scoring System-A Simple, Noninvasive Test to Identify Patients With Nonalcoholic Fatty Liver Disease With Advanced Fibrosis.
1/2020Cenicriviroc Treatment for Adults With Nonalcoholic Steatohepatitis and Fibrosis: Final Analysis of the Phase 2b CENTAUR Study.
1/2017Age as a Confounding Factor for the Accurate Non-Invasive Diagnosis of Advanced NAFLD Fibrosis.
3/2016Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR Phase 2b study design.
9/2014Variability in definitions of transaminase upper limit of the normal impacts the APRI performance as a biomarker of fibrosis in patients with chronic hepatitis C: "APRI c'est fini ?".
7/2011Prognostic value of liver fibrosis biomarkers: a meta-analysis.
1/2009The diagnostic value of combining carbohydrate-deficient transferrin, fibrosis, and steatosis biomarkers for the prediction of excessive alcohol consumption.
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Vlad Ratziu Research Topics

Disease

114Fibrosis (Cirrhosis)
04/2024 - 09/2002
90Non-alcoholic Fatty Liver Disease
04/2024 - 12/2005
53Liver Cirrhosis (Hepatic Cirrhosis)
04/2024 - 09/2002
33Liver Diseases (Liver Disease)
01/2024 - 12/2002
28Alcoholic Fatty Liver
12/2023 - 09/2007
25Fatty Liver
12/2023 - 12/2005
25Chronic Hepatitis C
11/2018 - 09/2002
16Inflammation (Inflammations)
03/2022 - 02/2010
12Insulin Resistance
11/2021 - 02/2004
11Type 2 Diabetes Mellitus (MODY)
05/2023 - 07/2008
8Infections
05/2015 - 12/2003
8Hepatitis C
03/2009 - 06/2002
7Hepatocellular Carcinoma (Hepatoma)
01/2024 - 05/2015
7Disease Progression
12/2023 - 09/2011
7Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2023 - 12/2003
7Hepatitis
01/2020 - 01/2006
7Chronic Hepatitis B
11/2014 - 08/2003
5Obesity
03/2022 - 08/2011
5Alcoholic Liver Diseases (Alcoholic Liver Disease)
11/2018 - 02/2005
4Weight Loss (Weight Reduction)
05/2023 - 08/2011
4Pruritus (Itching)
01/2023 - 12/2019
4Body Weight (Weight, Body)
01/2023 - 01/2019
3Weight Gain
10/2021 - 07/2008
3Liver Neoplasms (Liver Cancer)
08/2021 - 12/2003
3Dyslipidemias (Dyslipidemia)
12/2020 - 05/2015
3Cardiovascular Diseases (Cardiovascular Disease)
01/2016 - 02/2006
2Nausea
01/2024 - 10/2021
2Diarrhea
01/2024 - 10/2021
2Gilbert Disease
10/2023 - 01/2019
2Lipodystrophy
01/2023 - 01/2019
2COVID-19
03/2022 - 01/2020
2Neoplasms (Cancer)
01/2021 - 03/2003
2Abdominal Obesity
01/2020 - 03/2012
2Wolman Disease (Wolman's Disease)
01/2020 - 01/2018
2Cryptogenic Cirrhosis
12/2018 - 12/2016
2Morbid Obesity
01/2017 - 01/2012
2Chemical and Drug Induced Liver Injury
01/2017 - 02/2014
2Hypertension (High Blood Pressure)
01/2016 - 05/2015
2Overweight
05/2015 - 12/2003

Drug/Important Bio-Agent (IBA)

81Biomarkers (Surrogate Marker)IBA
12/2023 - 09/2002
12nasIBA
12/2023 - 02/2010
11Aspartate Aminotransferases (Aspartate Transaminase)IBA
04/2024 - 01/2008
10Insulin (Novolin)FDA Link
01/2021 - 07/2008
10Transaminases (Aminotransferases)IBA
01/2020 - 08/2003
8EnzymesIBA
01/2023 - 08/2011
8LipidsIBA
05/2022 - 08/2013
8Alanine Transaminase (SGPT)IBA
01/2019 - 06/2004
8Ribavirin (Virazole)FDA LinkGeneric
05/2015 - 07/2003
7obeticholic acidIBA
11/2023 - 05/2016
7Proteins (Proteins, Gene)FDA Link
05/2023 - 01/2019
7CollagenIBA
05/2023 - 10/2018
7Triglycerides (Triacylglycerol)IBA
12/2020 - 07/2003
6semaglutideIBA
12/2023 - 01/2019
6cenicrivirocIBA
10/2023 - 03/2016
6BilirubinIBA
10/2023 - 01/2003
6HaptoglobinsIBA
03/2022 - 01/2003
6Glucose (Dextrose)FDA LinkGeneric
01/2022 - 12/2003
6Antiviral Agents (Antivirals)IBA
08/2021 - 12/2003
6InterferonsIBA
04/2015 - 12/2003
5Apolipoprotein A-I (Apolipoprotein A1)IBA
03/2022 - 01/2003
5ThiazolidinedionesIBA
11/2014 - 02/2010
5gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
06/2010 - 01/2003
4RNA (Ribonucleic Acid)IBA
01/2023 - 06/2002
4Peroxisome Proliferator-Activated Receptors (PPAR)IBA
12/2021 - 12/2013
3tropifexorIBA
10/2023 - 01/2020
3Complement C3 (C3 Complement)IBA
08/2023 - 09/2019
3Protein Kinases (Protein Kinase)IBA
01/2023 - 01/2020
3LeptinIBA
12/2022 - 10/2009
3Syntex adjuvant formulationIBA
02/2022 - 01/2020
3Protons (Proton)IBA
11/2021 - 03/2003
3simtuzumabIBA
12/2019 - 05/2016
3C-Reactive ProteinIBA
01/2019 - 10/2009
32- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA
05/2016 - 12/2013
3Rosiglitazone (Avandia)FDA Link
11/2014 - 07/2008
3AdiponectinIBA
03/2012 - 07/2008
3adefovirIBA
03/2012 - 01/2005
3Lamivudine (Epivir)FDA Link
09/2005 - 12/2003
2resmetiromIBA
01/2024 - 01/2024
2Hypoglycemic Agents (Hypoglycemics)IBA
05/2023 - 01/2016
2Glucagon-Like Peptide 1 (GLP 1)IBA
01/2023 - 01/2019
2LDL CholesterolIBA
01/2023 - 08/2013
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2023 - 01/2016
2Monoclonal AntibodiesIBA
01/2022 - 10/2018
2TransferasesIBA
08/2021 - 06/2006
2CC ChemokinesIBA
01/2020 - 03/2016
2Choline (Choline Chloride)IBA
01/2020 - 12/2013
2Metformin (Glucophage)FDA LinkGeneric
01/2019 - 12/2010
2CreatinineIBA
10/2018 - 01/2016
2Interferon-alpha (Interferon Alfa)IBA
05/2015 - 12/2004
2asunaprevirIBA
12/2014 - 01/2013
2Dihydrotachysterol (AT 10)IBA
04/2014 - 10/2013
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2013 - 04/2003
2Transforming Growth Factor beta (TGF-beta)IBA
12/2013 - 12/2002
2Transcription Factors (Transcription Factor)IBA
06/2012 - 12/2002
2Hepatitis B e AntigensIBA
03/2012 - 07/2008

Therapy/Procedure

33Therapeutics
12/2023 - 04/2003
7Drug Therapy (Chemotherapy)
12/2023 - 08/2011
6Liver Transplantation
07/2023 - 05/2015
4Bariatric Surgery
05/2023 - 01/2017
2Aftercare (After-Treatment)
01/2022 - 10/2013