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Edward A Ratovitski Selected Research

Cisplatin (Platino)

5/2015Phospho-ΔNp63α-responsive microRNAs contribute to the regulation of necroptosis in squamous cell carcinoma upon cisplatin exposure.
1/2015Delta Np63 alpha – Responsive microRNA Modulate the Expression of Metabolic Enzymes.
11/2013Phospho-ΔNp63α regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation.
8/2013Phospho-ΔNp63α-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death.
2/2013Phospho-ΔNp63α/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure.
10/2012Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance.
6/2012Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance.
3/2012Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation.
11/2011Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposure.
12/2010Phosphorylated TP63 induces transcription of RPN13, leading to NOS2 protein degradation.
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Edward A Ratovitski Research Topics

Disease

21Neoplasms (Cancer)
04/2017 - 10/2006
12Squamous Cell Carcinoma (Epidermoid Carcinoma)
08/2016 - 12/2010
4Carcinogenesis
11/2013 - 10/2006
3Squamous Cell Carcinoma of Head and Neck
02/2011 - 10/2004
3Breast Neoplasms (Breast Cancer)
08/2008 - 10/2006
2Glioblastoma (Glioblastoma Multiforme)
01/2017 - 08/2016
2Astrocytoma (Pilocytic Astrocytoma)
01/2017 - 01/2015
2Colorectal Neoplasms (Colorectal Cancer)
08/2016 - 10/2012
2Esophageal Squamous Cell Carcinoma
05/2011 - 02/2010
2Mitochondrial Diseases (Mitochondrial Disease)
07/2010 - 02/2010
1Head and Neck Neoplasms (Head and Neck Cancer)
08/2013
1Ataxia Telangiectasia (Louis Bar Syndrome)
03/2012
1Lung Neoplasms (Lung Cancer)
09/2010
1Urinary Bladder Neoplasms (Bladder Cancer)
08/2008
1Autosomal Dominant 5 Deafness
05/2008

Drug/Important Bio-Agent (IBA)

14Proteins (Proteins, Gene)FDA Link
01/2017 - 08/2008
11Cisplatin (Platino)FDA LinkGeneric
05/2015 - 12/2010
7MicroRNAs (MicroRNA)IBA
05/2015 - 10/2012
4ChromatinIBA
01/2017 - 09/2010
4SmokeIBA
05/2011 - 07/2010
3dehydroleucodineIBA
01/2017 - 01/2015
3Transcription Factors (Transcription Factor)IBA
06/2012 - 09/2010
2LuciferasesIBA
01/2017 - 08/2016
2PlatinumIBA
05/2015 - 10/2012
2EnzymesIBA
01/2015 - 01/2014
2Protein Isoforms (Isoforms)IBA
03/2012 - 12/2010
2COOH-terminal signal transamidaseIBA
08/2008 - 10/2006
2Messenger RNA (mRNA)IBA
08/2008 - 05/2008
1AntibodiesIBA
01/2017
1Tumor Protein p73IBA
01/2017
1Complementary DNA (cDNA)IBA
01/2017
1chromomycin A2IBA
08/2016
1psammaplin AIBA
08/2016
1ilimaquinoneIBA
08/2016
1Cytostatic AgentsIBA
01/2015
1ElementsIBA
02/2013
1coactivator-associated arginine methyltransferase 1IBA
02/2013
1Co-Repressor ProteinsIBA
02/2013
1Amino AcidsFDA Link
10/2012
1LipidsIBA
10/2012
1NucleotidesIBA
10/2012
1CarbohydratesIBA
10/2012
1DNA-Binding Proteins (DNA Binding Protein)IBA
05/2011
1Nitric Oxide Synthase (NO Synthase)IBA
02/2011
1NF-kappa B (NF-kB)IBA
09/2010
1Adenosine Triphosphate (ATP)IBA
07/2010
1API 2IBA
02/2010
1Pyruvic Acid (Pyruvate)IBA
02/2010
1Deoxyglucose (2 Deoxy D glucose)IBA
02/2010
1beta CateninIBA
02/2010
1Peptides (Polypeptides)IBA
02/2010
1Oxidoreductases (Dehydrogenase)IBA
02/2010
1Biomarkers (Surrogate Marker)IBA
05/2008
1Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
10/2006
1PaxillinIBA
10/2006
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2004

Therapy/Procedure

4Drug Therapy (Chemotherapy)
05/2015 - 12/2010
2Therapeutics
04/2017 - 10/2012