Rojina Ranjit Selected Research

Sarcopenia

11/2022	Acylated Ghrelin Receptor Agonist HM01 Decreases Lean Body and Muscle Mass, but Unacylated Ghrelin Protects against Redox-Dependent Sarcopenia.
1/2022	Scavenging mitochondrial hydrogen peroxide by peroxiredoxin 3 overexpression attenuates contractile dysfunction and muscle atrophy in a murine model of accelerated sarcopenia.
1/2022	Age Related Changes in Muscle Mass and Force Generation in the Triple Transgenic (3xTgAD) Mouse Model of Alzheimer's Disease.
12/2021	Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia.
1/2021	Transgenic expression of SOD1 specifically in neurons of Sod1 deficient mice prevents defects in muscle mitochondrial function and calcium handling.
12/2020	Restoration of Sarcoplasmic Reticulum Ca2+ ATPase (SERCA) Activity Prevents Age-Related Muscle Atrophy and Weakness in Mice.
1/2020	Molecular changes in transcription and metabolic pathways underlying muscle atrophy in the CuZnSOD null mouse model of sarcopenia.
1/2020	Targeting cPLA2 derived lipid hydroperoxides as a potential intervention for sarcopenia.
1/2019	Using MRI to measure in vivo free radical production and perfusion dynamics in a mouse model of elevated oxidative stress and neurogenic atrophy.

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Rojina Ranjit Research Topics

Disease

10	Muscular Atrophy (Muscle Atrophy) 11/2022 - 01/2019
9	Sarcopenia 11/2022 - 01/2019
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2022 - 02/2016
4	Atrophy 01/2022 - 01/2019
2	Cognitive Dysfunction 01/2022 - 01/2022
2	Muscle Weakness 01/2019 - 10/2018
1	Infections 12/2023
1	Body Weight (Weight, Body) 11/2022
1	Neuroinflammatory Diseases 01/2022
1	Alzheimer Disease (Alzheimer's Disease) 01/2022
1	Gliosis 01/2022
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022
1	Chronic Disease (Chronic Diseases) 02/2021
1	Hypertrophy 02/2021
1	Neoplasms (Cancer) 12/2020
1	Cachexia 12/2020
1	Lewis Lung Carcinoma 12/2020
1	Obesity 01/2018
1	Insulin Resistance 01/2018

Drug/Important Bio-Agent (IBA)

7	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 10/2018
3	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022 - 01/2020
2	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2022
2	AntioxidantsIBA 01/2022 - 02/2021
2	Free RadicalsIBA 02/2021 - 01/2019
2	Superoxide DismutaseIBA 02/2021 - 01/2020
2	Superoxides (Superoxide)IBA 01/2020 - 01/2019
2	Peptide Hydrolases (Proteases)FDA Link 01/2018 - 02/2016
1	IronIBA 12/2023
1	GhrelinIBA 11/2022
1	acyl-ghrelinIBA 11/2022
1	Hormones (Hormone)IBA 11/2022
1	HM01IBA 11/2022
1	Ghrelin ReceptorsIBA 11/2022
1	Peroxiredoxin IIIIBA 01/2022
1	A 17 (A-17)IBA 01/2022
1	Amyloid (Amyloid Fibrils)IBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	Neurotransmitter Agents (Neurotransmitter)IBA 01/2022
1	PresenilinsIBA 01/2022
1	PeroxidesIBA 12/2021
1	CatalaseIBA 12/2021
1	Superoxide Dismutase-1IBA 01/2021
1	Adenosine Triphosphate (ATP)IBA 01/2021
1	CalciumIBA 01/2021
1	Calcium-Transporting ATPases (Ca2+ ATPase)IBA 12/2020
1	Phosphates (Orthophosphate)IBA 12/2020
1	EnzymesIBA 12/2020
1	Phospholipases A2 (Phospholipase A2)IBA 01/2020
1	EicosanoidsIBA 01/2020
1	Arachidonic Acid (Vitamin F)IBA 01/2020
1	ProteomeIBA 01/2020
1	LipidsIBA 01/2020
1	Oxygen (Dioxygen)IBA 01/2019
1	Adenosine Triphosphatases (ATPase)IBA 01/2019

Therapy/Procedure

2	Therapeutics 12/2023 - 11/2022
2	Denervation 12/2021 - 01/2020