Sridhar Ramaswamy Selected Research

niraparib

12/2019	Niraparib activates interferon signaling and potentiates anti-PD-1 antibody efficacy in tumor models.
12/2018	A comparative pharmacokinetic study of PARP inhibitors demonstrates favorable properties for niraparib efficacy in preclinical tumor models.

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Sridhar Ramaswamy Research Topics

Disease

58	Neoplasms (Cancer) 01/2021 - 09/2002
20	Breast Neoplasms (Breast Cancer) 01/2019 - 09/2002
13	Neoplasm Metastasis (Metastasis) 08/2017 - 06/2004
10	Melanoma (Melanoma, Malignant) 01/2018 - 06/2002
5	Carcinogenesis 01/2019 - 06/2005
4	Circulating Neoplastic Cells 01/2018 - 11/2012
4	Pancreatic Neoplasms (Pancreatic Cancer) 08/2015 - 07/2012
3	Prostatic Neoplasms (Prostate Cancer) 01/2019 - 11/2012
3	Lung Neoplasms (Lung Cancer) 01/2017 - 12/2014
2	Triple Negative Breast Neoplasms 01/2021 - 08/2017
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2019 - 12/2005
2	Adenocarcinoma 06/2016 - 07/2013
2	Hypoxia (Hypoxemia) 01/2016 - 12/2005
1	Infections 11/2023
1	Endometrial Neoplasms (Endometrial Cancer) 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 12/2019
1	Neoplasm Micrometastasis 01/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Pathologic Complete Response 08/2017
1	Genomic Instability 12/2016
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 03/2015
1	Cholangiocarcinoma 09/2014
1	Liver Neoplasms (Liver Cancer) 09/2014

Drug/Important Bio-Agent (IBA)

11	RNA (Ribonucleic Acid)IBA 01/2019 - 07/2012
10	Proteins (Proteins, Gene)FDA Link 01/2019 - 09/2002
7	Estrogen ReceptorsIBA 01/2018 - 09/2002
6	Biomarkers (Surrogate Marker)IBA 03/2017 - 02/2010
5	Poly(ADP-ribose) Polymerase InhibitorsIBA 12/2019 - 03/2012
5	Transcription Factors (Transcription Factor)IBA 03/2017 - 08/2003
5	Phosphotransferases (Kinase)IBA 05/2015 - 12/2004
4	PlatinumIBA 01/2021 - 12/2018
3	AntibodiesIBA 01/2021 - 07/2003
3	LigandsIBA 01/2021 - 01/2018
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2021 - 11/2012
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 12/2018 - 03/2012
3	Androgen Receptors (Androgen Receptor)IBA 01/2018 - 11/2012
3	AndrogensIBA 01/2018 - 11/2012
3	MicroRNAs (MicroRNA)IBA 06/2016 - 12/2013
3	Messenger RNA (mRNA)IBA 01/2016 - 07/2003
3	DNA (Deoxyribonucleic Acid)IBA 12/2015 - 05/2003
3	ChromatinIBA 09/2015 - 06/2002
3	ErbB Receptors (EGF Receptor)IBA 03/2015 - 03/2014
2	niraparibIBA 12/2019 - 12/2018
2	Immune Checkpoint InhibitorsIBA 12/2019 - 01/2018
2	PlasticsIBA 01/2019 - 08/2017
2	Oncogene Proteins (Oncogene Protein)IBA 01/2018 - 02/2010
2	Estrogens (Estrogen)FDA Link 03/2017 - 08/2009
2	IntegrinsIBA 01/2017 - 02/2015
2	CytokinesIBA 01/2017 - 12/2014
2	Ligases (Synthetase)IBA 11/2016 - 09/2002
2	UbiquitinIBA 11/2016 - 09/2002
2	Cadherins (E-Cadherin)IBA 05/2015 - 06/2004
2	Tyrosine Kinase InhibitorsIBA 03/2015 - 12/2014
2	Drug CombinationsIBA 12/2014 - 07/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2013 - 12/2005
2	Cyclin-Dependent Kinases (cdk Proteins)IBA 11/2012 - 07/2005
1	16S Ribosomal RNAIBA 11/2023
1	Programmed Cell Death 1 ReceptorIBA 01/2021
1	dostarlimabIBA 01/2021
1	InterferonsIBA 12/2019
1	Interferon-gamma (Interferon, gamma)IBA 12/2019
1	Celecoxib (Celebrex)FDA Link 01/2019
1	Dinoprostone (PGE2)FDA Link 01/2019
1	Prolactin Receptors (Prolactin Receptor)IBA 01/2019
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2019
1	ProlactinIBA 01/2019
1	TSR-033IBA 01/2019
1	olaparibIBA 12/2018
1	Epidermal Growth Factor (EGF)IBA 03/2017
1	Small Interfering RNA (siRNA)IBA 03/2017
1	CarcinogensIBA 01/2017
1	GlobinsIBA 01/2017
1	NAD (NADH)IBA 06/2016
1	SirtuinsIBA 06/2016
1	Histone Deacetylases (Histone Deacetylase)IBA 06/2016
1	human ERBB2 proteinIBA 01/2016
1	Paclitaxel (Taxol)FDA LinkGeneric 01/2016
1	Polytetrafluoroethylene (Teflon)FDA Link 08/2015
1	Co-Repressor ProteinsIBA 06/2015
1	(5- (2,4- bis((3S)- 3- methylmorpholin- 4- yl)pyrido(2,3- d)pyrimidin- 7- yl)- 2- methoxyphenyl)methanolIBA 03/2015
1	navitoclaxIBA 03/2015
1	Mechanistic Target of Rapamycin Complex 2IBA 02/2015
1	PLX 4720IBA 01/2015
1	cediranib (AZD2171)IBA 01/2015
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 12/2014
1	Anaplastic Lymphoma KinaseIBA 12/2014
1	EpitopesIBA 09/2014
1	alpha-hydroxyglutarateIBA 09/2014
1	DioxygenasesIBA 09/2014
1	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 09/2014
1	gamma Catenin (Plakoglobin)IBA 08/2014
1	Tamoxifen FDA LinkGeneric 05/2014
1	Temozolomide (Temodar)FDA LinkGeneric 03/2014

Therapy/Procedure

18	Therapeutics 12/2019 - 09/2002
7	Drug Therapy (Chemotherapy) 01/2021 - 07/2005
2	Lab-On-A-Chip Devices 07/2015 - 07/2012
1	Aftercare (After-Treatment) 08/2017
1	Neoadjuvant Therapy 08/2017
1	Heterologous Transplantation (Xenotransplantation) 01/2016
1	Transplantation 12/2014