D S Postma Selected Research

Proteins (Proteins, Gene)

12/2015	Regulation of YKL-40 expression by corticosteroids: effect on pro-inflammatory macrophages in vitro and its modulation in COPD in vivo.
1/2012	Childhood overweight and asthma symptoms, the role of pro-inflammatory proteins.
4/2010	Novel strategy to identify genetic risk factors for COPD severity: a genetic isolate.
2/2010	TLR-related pathway analysis: novel gene-gene interactions in the development of asthma and atopy.
9/2006	Altered expression of the Smad signalling pathway: implications for COPD pathogenesis.
11/2005	Effect of 1-year smoking cessation on airway inflammation in COPD and asymptomatic smokers.
5/2002	Multidrug resistance related molecules in human and murine lung.
1/2000	Ongoing airway inflammation in patients with COPD who do not currently smoke.

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D S Postma Research Topics

Disease

76	Asthma (Bronchial Asthma) 10/2018 - 01/2000
37	Chronic Obstructive Pulmonary Disease (COPD) 01/2018 - 01/2000
29	Inflammation (Inflammations) 01/2018 - 01/2000
9	Hypersensitivity (Allergy) 11/2016 - 05/2001
8	Respiratory Hypersensitivity 05/2016 - 10/2000
8	Airway Obstruction (Choking) 02/2014 - 09/2000
6	Airway Remodeling 01/2017 - 09/2007
3	Rhinitis 01/2018 - 03/2001
3	Eczema 08/2015 - 09/2002
3	Dyspnea (Shortness of Breath) 12/2014 - 04/2010
3	Infections 06/2011 - 05/2007
3	Eosinophilia 03/2005 - 06/2003
3	Bronchiolitis Obliterans Syndrome 02/2001 - 06/2000
2	Pneumonia (Pneumonitis) 01/2018 - 01/2016
2	Respiratory Tract Diseases (Respiratory Tract Disease) 01/2018 - 01/2017
2	Seasonal Allergic Rhinitis (Hay Fever) 12/2009 - 03/2001
2	Necrosis 01/2007 - 01/2000
2	Allergic Rhinitis 06/2002 - 03/2001
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Frailty 01/2017
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2017
1	Virus Diseases (Viral Diseases) 01/2016
1	Overweight 01/2016
1	Obesity 08/2012
1	Wounds and Injuries (Trauma) 02/2012
1	Alcoholism (Alcohol Abuse) 01/2012
1	Pediatric Obesity 01/2012
1	Body Weight (Weight, Body) 01/2012

Drug/Important Bio-Agent (IBA)

30	Adrenal Cortex Hormones (Corticosteroids)IBA 05/2017 - 01/2001
16	Methacholine Chloride (Methacholine)FDA Link 04/2016 - 09/2000
14	AllergensIBA 01/2018 - 09/2000
13	Immunoglobulin E (IgE)IBA 01/2018 - 11/2000
12	SmokeIBA 01/2018 - 01/2000
11	Adenosine Monophosphate (AMP)IBA 03/2011 - 05/2000
10	Adenosine (Adenocard)FDA LinkGeneric 09/2008 - 05/2000
9	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2014 - 09/2000
8	Budesonide (Pulmicort)FDA LinkGeneric 01/2018 - 01/2000
8	Fluticasone (Cutivate)FDA LinkGeneric 01/2018 - 12/2001
8	Bronchodilator Agents (Bronchodilators)IBA 01/2017 - 08/2000
8	Proteins (Proteins, Gene)FDA Link 12/2015 - 01/2000
8	CytokinesIBA 09/2008 - 07/2000
6	Histamine (Histamine Dihydrochloride)FDA Link 09/2010 - 10/2000
6	Formoterol Fumarate (Oxis)FDA Link 01/2003 - 01/2000
5	SteroidsIBA 06/2015 - 10/2001
4	InterleukinsIBA 09/2008 - 01/2000
3	Interleukin-13IBA 10/2018 - 09/2001
3	prednylidene (Pred)IBA 04/2016 - 06/2001
3	OvalbuminIBA 12/2015 - 09/2001
3	GlucocorticoidsIBA 06/2015 - 01/2000
3	GoldIBA 04/2010 - 01/2006
3	ciclesonide FDA Link 08/2009 - 06/2001
3	Interleukin-4 (Interleukin 4)IBA 12/2007 - 01/2000
2	EnzymesIBA 01/2018 - 01/2000
2	AntibodiesIBA 01/2018 - 02/2011
2	Messenger RNA (mRNA)IBA 12/2016 - 09/2004
2	Cadherins (E-Cadherin)IBA 11/2011 - 04/2010
2	Immunoglobulins (Immunoglobulin)IBA 11/2011 - 09/2008
2	AutoantibodiesIBA 05/2011 - 02/2011
2	DecorinIBA 05/2011 - 09/2006
2	CollagenIBA 05/2011 - 01/2010
2	Metalloproteases (Metalloproteinases)IBA 04/2011 - 04/2010
2	Transforming Growth Factor beta1 (TGF beta 1)IBA 04/2010 - 09/2006
2	Prednisolone (Predate)FDA LinkGeneric 08/2009 - 07/2002
2	Purinergic P1 Receptors (Adenosine Receptor)IBA 09/2008 - 01/2008
2	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2007 - 12/2000
2	Interleukin-6 (Interleukin 6)IBA 12/2007 - 12/2000
2	Interleukin-5 (Interleukin 5)IBA 12/2007 - 10/2002
2	Carbon MonoxideIBA 12/2007 - 04/2003
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2006 - 01/2000
2	Salmeterol Xinafoate (Serevent)FDA Link 11/2005 - 06/2005
2	Terbutaline (Brethaire)FDA LinkGeneric 01/2003 - 01/2001
2	Anti-Allergic Agents (Antiallergic Agents)IBA 09/2002 - 01/2002
2	Reactive Nitrogen SpeciesIBA 01/2002 - 09/2001
2	Phenobarbital (Luminal)FDA Link 01/2002 - 01/2000
2	Interleukin-8 (Interleukin 8)IBA 12/2000 - 01/2000
1	MetallothioneinIBA 01/2018
1	XenobioticsIBA 01/2018
1	Urokinase Plasminogen Activator ReceptorsIBA 03/2017
1	Glutathione (Reduced Glutathione)IBA 01/2017
1	TransferasesIBA 01/2017
1	alpha-latrotoxin receptorIBA 01/2017
1	Intergenic DNA (Junk DNA)IBA 01/2017
1	CholesterolIBA 01/2016
1	ChitinasesIBA 12/2015
1	Dexamethasone (Maxidex)FDA LinkGeneric 12/2015
1	GasesIBA 02/2014
1	SolventsIBA 02/2014
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2013
1	MineralocorticoidsIBA 12/2012
1	Glucocorticoid Receptors (Glucocorticoid Receptor)IBA 12/2012
1	Biomarkers (Surrogate Marker)IBA 09/2012
1	ResveratrolIBA 02/2012
1	C-Reactive ProteinIBA 01/2012
1	Complement System Proteins (Complement)IBA 01/2012
1	Nicotine FDA Link 01/2012

Therapy/Procedure

11	Therapeutics 11/2016 - 01/2000
4	Lung Transplantation 02/2001 - 06/2000
2	Medical Day Care (Partial Hospitalization) 12/2013 - 10/2003
1	Polypharmacy 01/2017
1	Precision Medicine 11/2016