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John S Penn Selected Research

Cytochrome P-450 CYP2C9

6/2014The role of cytochrome P450 epoxygenases in retinal angiogenesis.

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John S Penn Research Topics

Disease

15Hypoxia (Hypoxemia)
12/2023 - 11/2004
12Retinal Neovascularization
12/2023 - 12/2003
12Inflammation (Inflammations)
01/2022 - 03/2013
10Choroidal Neovascularization
09/2023 - 11/2009
9Diabetic Retinopathy (Retinopathy, Diabetic)
01/2022 - 06/2014
9Retinopathy of Prematurity (Retrolental Fibroplasia)
06/2014 - 04/2003
6Pathologic Neovascularization
01/2021 - 12/2003
5Leukostasis
01/2020 - 01/2015
3Macular Degeneration (Age-Related Maculopathy)
09/2023 - 12/2018
3Hyperglycemia
01/2023 - 01/2018
3Burns
02/2011 - 10/2010
2Rupture
09/2023 - 12/2010
2Ischemia
01/2023 - 10/2013
2Hyperoxia
06/2014 - 11/2004
2Eye Diseases (Eye Disease)
02/2010 - 05/2004
1Hyperlipidemias (Hyperlipidemia)
01/2023
1Neuroinflammatory Diseases
01/2023
1Hypertension (High Blood Pressure)
01/2023
1Dyslipidemias (Dyslipidemia)
01/2022
1Retinal Degeneration
09/2019
1Retinal Diseases
01/2018
1Disease Progression
01/2018
1Retinal Vein Occlusion
01/2017
1Vascular Diseases (Vascular Disease)
12/2016
1Macular Edema
11/2014

Drug/Important Bio-Agent (IBA)

28Retinaldehyde (Retinal)IBA
01/2023 - 04/2003
11Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2016 - 11/2006
9Oxygen (Dioxygen)IBA
01/2016 - 02/2004
7Messenger RNA (mRNA)IBA
12/2023 - 11/2013
6CytokinesIBA
01/2022 - 01/2015
5Fatty Acids (Saturated Fatty Acids)IBA
01/2023 - 12/2016
4Prostaglandins EIBA
10/2010 - 02/2010
3LipidsIBA
12/2023 - 01/2018
3Nonesterified Fatty Acids (NEFA)IBA
01/2023 - 01/2020
3AcidsIBA
01/2021 - 11/2007
311,12-epoxy-5,8,14-eicosatrienoic acidIBA
01/2021 - 06/2014
3GoldIBA
05/2019 - 01/2017
3RNA (Ribonucleic Acid)IBA
01/2018 - 02/2010
3Proteins (Proteins, Gene)FDA Link
11/2013 - 01/2006
2InflammasomesIBA
09/2023 - 01/2022
2Glucose (Dextrose)FDA LinkGeneric
01/2023 - 01/2018
2Palmitic Acid (Hexadecanoic Acid)IBA
01/2023 - 01/2018
2CytochromesIBA
09/2021 - 01/2021
219,20-epoxydocosapentaenoic acidIBA
01/2021 - 12/2016
2Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
01/2021 - 06/2014
2Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2020 - 01/2015
2GSK0660IBA
01/2020 - 01/2015
2Transcription Factors (Transcription Factor)IBA
01/2020 - 01/2015
2Retinal Pigments (Pigments, Visual)IBA
09/2019 - 12/2016
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
12/2018 - 01/2018
2Biomarkers (Surrogate Marker)IBA
01/2018 - 03/2013
2pimonidazoleIBA
01/2017 - 01/2016
1Small Interfering RNA (siRNA)IBA
12/2023
1Angiotensin IIIBA
01/2023
1Dihydrotachysterol (AT 10)IBA
01/2022
1ChemokinesIBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
12/2018
1Interleukin-8 (Interleukin 8)IBA
12/2016
1Linoleic Acid (Linoleate)IBA
12/2016
1Oleic Acid (Oleate)IBA
12/2016
1Interleukin-6 (Interleukin 6)IBA
12/2016
1Protein Isoforms (Isoforms)IBA
11/2015
1Neutralizing AntibodiesIBA
08/2014
1EndoglinIBA
08/2014
1Cytochrome P-450 CYP2C9IBA
06/2014
1ProadifenIBA
06/2014
1IntegrinsIBA
06/2014
1cytochrome P-450 CYP2C subfamilyIBA
06/2014
1Cytochrome P-450 CYP2C8IBA
06/2014
1Tacrolimus (Prograf)FDA LinkGeneric
10/2013
1nutlin 3IBA
10/2013
1KetorolacIBA
10/2010
1Lubricant Eye Drops (Artificial Tears)IBA
10/2010
1ProstaglandinsIBA
07/2010
1amfenacIBA
02/2010
1nepafenac (Nevanac)FDA Link
02/2010
1SC 560IBA
02/2010
1Celecoxib (Celebrex)FDA Link
02/2010
1Phospholipases (Phospholipase)IBA
02/2010
1p38 Mitogen-Activated Protein KinasesIBA
02/2010
1Conditioned Culture MediaIBA
02/2010
1L-161982IBA
11/2009
1Arachidonic Acid (Vitamin F)IBA
11/2007
1ManganeseIBA
10/2007
1Eosine Yellowish-(YS) (Eosin)IBA
02/2007
1Ro 31-9790IBA
02/2007
1Matrix Metalloproteinases (MMPs)IBA
02/2007
1Apyrase (ATP Diphosphatase)IBA
02/2007
1Matrix Metalloproteinase InhibitorsIBA
02/2007
1Hematoxylin (Haematoxylon)IBA
02/2007
1src-Family KinasesIBA
11/2006
1AntibodiesIBA
05/2006
14,5,6,7-tetrabromobenzotriazoleIBA
05/2006
1Emodin (Archin)IBA
05/2006

Therapy/Procedure

11Lasers (Laser)
09/2023 - 11/2009
4Therapeutics
01/2023 - 12/2003
2Intravitreal Injections
02/2007 - 12/2003
1Glycemic Control
01/2023
1Intraperitoneal Injections
01/2022
1Cell- and Tissue-Based Therapy (Cell Therapy)
09/2019