James T Pearson Selected Research

Heart Failure

11/2020	Contribution of afferent pathway to vagal nerve stimulation-induced myocardial interstitial acetylcholine release in rats.
12/2019	Diastolic dysfunction is initiated by cardiomyocyte impairment ahead of endothelial dysfunction due to increased oxidative stress and inflammation in an experimental prediabetes model.
1/2017	Cardiac vagal control in a knock-in mouse model of dilated cardiomyopathy with a troponin mutation.
5/2013	Impaired pulmonary blood flow distribution in congestive heart failure assessed using synchrotron radiation microangiography.

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James T Pearson Research Topics

Disease

15	Hypoxia (Hypoxemia) 12/2021 - 07/2003
9	Pulmonary Hypertension 01/2021 - 11/2005
6	Fibrosis (Cirrhosis) 01/2021 - 08/2013
6	Ischemia 12/2020 - 04/2006
4	Inflammation (Inflammations) 01/2021 - 02/2013
4	Heart Failure 11/2020 - 05/2013
3	Diabetic Cardiomyopathies 11/2017 - 03/2013
3	Vascular Remodeling 09/2013 - 09/2011
2	Cardiomyopathies (Cardiomyopathy) 01/2023 - 12/2017
2	Hypertrophy 01/2021 - 11/2017
2	Pulmonary Arterial Hypertension 01/2021 - 04/2011
2	Peripheral Arterial Disease 12/2020 - 10/2020
2	Myocardial Ischemia (Ischemic Heart Diseases) 11/2019 - 01/2017
2	Coronary Occlusion 11/2019 - 01/2017
2	Hyperoxia 01/2019 - 12/2013
2	Infarction (Infarctions) 01/2017 - 01/2015
2	Right Ventricular Hypertrophy 09/2013 - 09/2011
1	Congenital Diaphragmatic Hernias 11/2023
1	Cardiomegaly (Heart Hypertrophy) 01/2023
1	Chorioamnionitis 01/2022
1	Hypotension (Low Blood Pressure) 01/2022
1	Hepatitis B 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Hypertension (High Blood Pressure) 01/2021
1	Insulin Resistance 01/2021
1	Diabetes Mellitus 11/2020
1	Microvascular Rarefaction 11/2020
1	Pulmonary Atelectasis 11/2020
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2020
1	Prediabetic State (Prediabetes) 12/2019
1	Congenital Heart Defects (Congenital Heart Defect) 01/2019
1	Vascular System Injuries 01/2019
1	Respiratory Insufficiency (Respiratory Failure) 01/2018

Drug/Important Bio-Agent (IBA)

6	GhrelinIBA 01/2021 - 09/2011
4	Serotonin (5 Hydroxytryptamine)IBA 12/2021 - 09/2013
4	Vasodilator Agents (Vasodilators)IBA 01/2021 - 01/2014
4	NG-Nitroarginine Methyl Ester (L-NAME)IBA 07/2013 - 11/2005
3	CytokinesIBA 01/2022 - 12/2013
3	MonocrotalineIBA 01/2021 - 07/2009
3	Myosins (Myosin)IBA 12/2019 - 03/2013
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2019 - 11/2005
2	Atrial Natriuretic Factor (ANF)IBA 01/2022 - 11/2017
2	Semaxinib (SU5416)IBA 01/2021 - 01/2021
2	MicroRNAs (MicroRNA)IBA 11/2020 - 01/2017
2	OsteopontinIBA 01/2020 - 11/2017
2	3-nitrotyrosineIBA 01/2020 - 08/2013
2	Biomarkers (Surrogate Marker)IBA 01/2020 - 12/2013
2	rho-Associated KinasesIBA 12/2019 - 04/2011
2	Monoamine Oxidase (MAO)IBA 11/2019 - 01/2017
2	Vasoconstrictor AgentsIBA 01/2019 - 01/2014
2	Endothelin-1 (Endothelin 1)IBA 01/2019 - 09/2011
2	Proteins (Proteins, Gene)FDA Link 09/2017 - 12/2014
2	Fluoxetine (Prozac)FDA LinkGeneric 01/2017 - 09/2013
2	Acetylcholine (Acetylcholine Chloride)FDA Link 05/2013 - 02/2012
2	Nitric Oxide Synthase (NO Synthase)IBA 02/2012 - 07/2003
1	Amino Acids FDA Link 01/2023
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2023
1	Histones (Histone)IBA 01/2023
1	ChromatinIBA 01/2023
1	Lysine (L-Lysine)FDA Link 01/2023
1	atrial natriuretic factor receptor AIBA 01/2022
1	Magnesium Sulfate (Sulfate, Magnesium)FDA LinkGeneric 01/2022
1	Dialysis SolutionsIBA 12/2021
1	Sodium CyanideIBA 12/2021
1	Growth Hormone (Somatotropin)IBA 01/2021
1	hexarelinIBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 01/2021
1	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 01/2021
1	Angiotensin Receptor AntagonistsIBA 01/2021
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2021
1	carbazoleIBA 01/2021
1	Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA 01/2021
1	SecretagoguesIBA 01/2021
1	SaltsIBA 01/2021
1	Qingdai compoundIBA 01/2021
1	Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA 01/2021
1	Blood Glucose (Blood Sugar)IBA 01/2020
1	ConnectinIBA 12/2019
1	Soluble Guanylyl CyclaseIBA 12/2019
1	Hydroxyindoleacetic AcidIBA 11/2019
1	pseudoisocyanineIBA 11/2019
1	CorticosteroneIBA 11/2019
1	CationsIBA 11/2019
1	Galectin 3 (LGALS3)IBA 01/2019
1	Interleukin-1 (Interleukin 1)IBA 01/2019
1	LigandsIBA 01/2019
1	Metformin (Glucophage)FDA LinkGeneric 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	Endothelin Receptors (Endothelin Receptor)IBA 01/2019
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 01/2019
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 01/2019
1	acyl-ghrelinIBA 01/2019
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2019
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2019

Therapy/Procedure

12	Synchrotrons 01/2021 - 01/2008
3	Artificial Respiration (Mechanical Ventilation) 11/2023 - 01/2017
3	Therapeutics 01/2022 - 02/2013
1	Vagus Nerve Stimulation 11/2020
1	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 11/2020
1	Injections 01/2019