Luis A Ortiz Selected Research

Therapeutics

3/2023	Mesenchymal Stem Cells from COPD Patients Are Capable of Restoring Elastase-Induced Emphysema in a Murine Experimental Model.
1/2021	Metabolic Adaptation of Macrophages as Mechanism of Defense against Crystalline Silica.
1/2020	International Society for Extracellular Vesicles and International Society for Cell and Gene Therapy statement on extracellular vesicles from mesenchymal stromal cells and other cells: considerations for potential therapeutic agents to suppress coronavirus disease-19.
11/2018	Extracellular matrix in lung development, homeostasis and disease.
1/2014	Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report.
1/2011	Pneumonic tularemia in rabbits resembles the human disease as illustrated by radiographic and hematological changes after infection.
7/2008	Stem cells and cell therapies in lung biology and lung diseases.

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Luis A Ortiz Research Topics

Disease

10	Fibrosis (Cirrhosis) 01/2023 - 07/2002
9	Inflammation (Inflammations) 01/2022 - 09/2002
9	Lung Injury 01/2019 - 06/2002
8	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2023 - 09/2002
8	Lung Diseases (Lung Disease) 11/2018 - 07/2008
7	Silicosis 01/2023 - 01/2004
5	Idiopathic Pulmonary Fibrosis 01/2023 - 05/2009
1	Chronic Obstructive Pulmonary Disease (COPD) 03/2023
1	Emphysema 03/2023
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2023
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 01/2022
1	Pneumoconiosis 01/2021
1	COVID-19 01/2020
1	Acute Lung Injury 01/2019
1	Interstitial Lung Diseases (Interstitial Lung Disease) 10/2018
1	Vascular Diseases (Vascular Disease) 08/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 08/2013
1	Tularemia 01/2011
1	Lymphopenia (Lymphocytopenia) 01/2011
1	Infections 06/2007
1	Herpes Simplex 12/2004
1	Hypertension (High Blood Pressure) 02/2003
1	Body Weight (Weight, Body) 02/2003
1	Eosinophilia 09/2002
1	Pulmonary Hypertension 06/2002

Drug/Important Bio-Agent (IBA)

9	Silicon Dioxide (Silica)FDA LinkGeneric 01/2022 - 07/2002
8	Bleomycin (Blenoxane)FDA LinkGeneric 01/2023 - 06/2002
7	CollagenIBA 01/2023 - 09/2002
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2014 - 06/2002
4	CytokinesIBA 01/2021 - 04/2014
3	Proteins (Proteins, Gene)FDA Link 01/2023 - 06/2007
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 04/2014
2	4- ethoxymethylene- 2- phenyl- 2- oxazoline- 5- one (phOx)IBA 01/2022 - 04/2014
2	indium-bleomycinIBA 04/2014 - 06/2002
2	NF-kappa B (NF-kB)IBA 05/2009 - 06/2002
1	SmokeIBA 03/2023
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2023
1	Pancreatic Elastase (Elastase)IBA 03/2023
1	navitoclaxIBA 01/2023
1	InterferonsIBA 01/2022
1	Pattern Recognition ReceptorsIBA 01/2022
1	InflammasomesIBA 01/2022
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 11/2021
1	Interleukin-13IBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	Interleukin-33IBA 01/2019
1	AlarminsIBA 01/2019
1	Interleukin-4 (Interleukin 4)IBA 01/2019
1	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2019
1	Protein Tyrosine PhosphatasesIBA 10/2018
1	Tyrosine (L-Tyrosine)FDA Link 10/2018
1	Type I Tumor Necrosis Factor ReceptorsIBA 04/2014
1	Hydroxyproline (4 Hydroxyproline)IBA 04/2014
1	Alanine Transaminase (SGPT)IBA 01/2011
1	Biological Warfare AgentsIBA 01/2011
1	VaccinesIBA 01/2011
1	CholesterolIBA 01/2011
1	NF-KappaB Inhibitor alphaIBA 05/2009
1	Transcription Factors (Transcription Factor)IBA 05/2009
1	Matrix Metalloproteinases (MMPs)IBA 03/2008
1	Tissue Inhibitor of Metalloproteinase-1IBA 03/2008
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2007
1	Messenger RNA (mRNA)IBA 06/2007
1	Transforming Growth Factor beta (TGF-beta)IBA 08/2005
1	Ganciclovir (Cytovene)FDA LinkGeneric 12/2004
1	Thymidine KinaseIBA 12/2004
1	UteroglobinIBA 12/2004
1	Dexamethasone (Maxidex)FDA LinkGeneric 02/2003
1	Protein CIBA 09/2002
1	Surface-Active Agents (Surfactants)IBA 09/2002
1	Tumor Suppressor Protein p53IBA 09/2002
1	Becaplermin (PDGF-BB)FDA Link 09/2002
1	Enalapril FDA LinkGeneric 06/2002
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 06/2002
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 06/2002
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 06/2002
1	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 06/2002

Therapy/Procedure

7	Therapeutics 03/2023 - 07/2008
2	Cell- and Tissue-Based Therapy (Cell Therapy) 08/2013 - 07/2013
1	Lung Transplantation 05/2009
1	Intraperitoneal Injections 02/2003