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Tsutomu Ohta Selected Research

Poly(ADP-ribose) Polymerase Inhibitors

8/2016Synovial sarcoma cell lines showed reduced DNA repair activity and sensitivity to a PARP inhibitor.

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Tsutomu Ohta Research Topics

Disease

17Neoplasms (Cancer)
10/2022 - 07/2002
5Carcinogenesis
10/2022 - 08/2003
4Lung Neoplasms (Lung Cancer)
03/2008 - 05/2005
3Synovial Sarcoma (Synovioma)
08/2016 - 05/2004
3Neoplasm Metastasis (Metastasis)
05/2010 - 06/2004
3Carcinoma (Carcinomatosis)
12/2003 - 07/2002
2Chromosome Aberrations (Chromosome Abnormalities)
07/2014 - 10/2004
2Hepatocellular Carcinoma (Hepatoma)
10/2004 - 06/2004
2Colonic Neoplasms (Colon Cancer)
08/2004 - 08/2003
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2022
1Stomach Neoplasms (Stomach Cancer)
08/2020
1Ruptured Aneurysm
01/2016
1False Aneurysm (Pseudoaneurysm)
01/2016
1Cerebellar Ataxia (Dysmetria)
01/2016
1Abducens Nerve Diseases (Sixth Nerve Palsy)
01/2016
1Brain Stem Infarctions (Weber Syndrome)
01/2016
1Acoustic Neuroma (Acoustic Neurinoma)
01/2016
1Chromosomal Instability (Chromosome Stability)
07/2014
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
07/2014
1Aplastic Anemia (Anemia, Hypoplastic)
07/2014
1Sarcoma (Soft Tissue Sarcoma)
01/2013
1Breast Neoplasms (Breast Cancer)
10/2010
1Lymphoma (Lymphomas)
05/2010
1Pancreatic Neoplasms (Pancreatic Cancer)
04/2009
1Liver Neoplasms (Liver Cancer)
03/2009
1Fibrosis (Cirrhosis)
03/2009
1Chronic Hepatitis (Chronic Active Hepatitis)
03/2009
1Gallbladder Neoplasms (Gallbladder Cancer)
10/2008
1Intestinal Polyps
10/2007
1Hyperlipidemias (Hyperlipidemia)
10/2007
1Adenocarcinoma of Lung
07/2007
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
12/2006
1Male Infertility (Male Sterility)
05/2006
1Autosomal Dominant 5 Deafness
01/2006
1B-Cell Lymphoma (Lymphoma, B Cell)
11/2005
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
05/2005
1Adenocarcinoma
05/2005

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
04/2009 - 05/2004
7OligonucleotidesIBA
07/2007 - 07/2002
3Amino AcidsFDA Link
07/2014 - 05/2005
3Messenger RNA (mRNA)IBA
10/2007 - 08/2004
32- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA
08/2004 - 07/2002
3benzocycloheptapyridineIBA
08/2004 - 07/2002
2DNA (Deoxyribonucleic Acid)IBA
08/2020 - 07/2014
2Etoposide (VP 16)FDA LinkGeneric
08/2016 - 01/2006
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
08/2016 - 05/2003
2EnzymesIBA
04/2011 - 05/2003
2Small Interfering RNA (siRNA)IBA
10/2010 - 09/2008
2Complementary DNA (cDNA)IBA
03/2009 - 07/2002
2CarcinogensIBA
08/2004 - 07/2002
2Methylnitronitrosoguanidine (MNNG)IBA
12/2003 - 05/2003
16-methyladenineIBA
10/2022
1N-methyladenosineIBA
10/2022
1RNA (Ribonucleic Acid)IBA
10/2022
1Alkylating AgentsIBA
08/2016
1Temozolomide (Temodar)FDA LinkGeneric
08/2016
1Topoisomerase II InhibitorsIBA
08/2016
1Poly(ADP-ribose) Polymerase InhibitorsIBA
08/2016
1olaparibIBA
08/2016
1Valine (L-Valine)FDA Link
07/2014
1Isoleucine (L-Isoleucine)FDA Link
07/2014
11,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA
07/2014
1Stearoyl-CoA DesaturaseIBA
01/2013
1Macrophage Migration-Inhibitory FactorsIBA
01/2013
1RibonucleoproteinsIBA
04/2011
1Telomerase (Telomerase Reverse Transcriptase)IBA
04/2011
1Guanine Nucleotide Exchange Factors (Guanine Nucleotide Exchange Factor)IBA
05/2010
1Guanylate KinasesIBA
05/2010
1Adenylyl Cyclases (Adenylyl Cyclase)IBA
04/2009
1CAP1-6DIBA
04/2009
1alpha-Fetoproteins (alpha-Fetoprotein)IBA
03/2009
1Vitamin KFDA Link
03/2009
1Fluorouracil (Carac)FDA LinkGeneric
10/2008
1Indicators and Reagents (Reagents)IBA
09/2008
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
09/2008
1Cisplatin (Platino)FDA LinkGeneric
03/2008
1Triglycerides (Triacylglycerol)IBA
10/2007
1Indomethacin (Indometacin)FDA LinkGeneric
10/2007
1Cyclooxygenase InhibitorsIBA
10/2007
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
10/2007
1PPAR alphaIBA
10/2007
1LipidsIBA
10/2007
1Biomarkers (Surrogate Marker)IBA
07/2007
1ErbB Receptors (EGF Receptor)IBA
07/2007
1Epidermal Growth Factor (EGF)IBA
07/2007
1SYT-SSX fusion proteinIBA
02/2007
1Immunoglobulins (Immunoglobulin)IBA
05/2006
1Cell Adhesion MoleculesIBA
05/2006
1Cysteine (L-Cysteine)FDA Link
03/2006
1Glycine (Aminoacetic Acid)FDA LinkGeneric
03/2006
1ChromatinIBA
01/2006
1Interleukin-6 (Interleukin 6)IBA
11/2005
1alanyl-alanyl-alanineIBA
05/2005
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
05/2005
1prolyl-proline (Pro-Pro)IBA
05/2005
1arginylarginine (Arg-Arg)IBA
05/2005
1A-Form DNA (A-DNA)IBA
05/2005

Therapy/Procedure

2Drug Therapy (Chemotherapy)
08/2016 - 10/2008
1Activities of Daily Living (ADL)
01/2016
1Radiotherapy
01/2016