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Jong Min Oh Selected Research

Monoamine Oxidase (MAO)

1/2024Machine learning driven web-based app platform for the discovery of monoamine oxidase B inhibitors.
1/2024Enzyme Inhibition Assays for Monoamine Oxidase.
12/2023Repurposing Azoles to Resolve Serotogenic Toxicity Associated with Linezolid to Combat Multidrug-Resistant Tuberculosis.
8/2023Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease.
8/2023Halogenated class of oximes as a new class of monoamine oxidase-B inhibitors for the treatment of Parkinson's disease: Synthesis, biochemistry, and molecular dynamics study.
2/2023Development of Isopropyl-Tailed Chalcones as a New Class of Selective MAO-B Inhibitors for the Treatment of Parkinson's Disorder.
1/2023Exploration of a new class of monoamine oxidase B inhibitors by assembling benzyloxy pharmacophore on halogenated chalcones.
9/2022Synthesis of 4-substituted benzyl-2-triazole-linked-tryptamine-paeonol derivatives and evaluation of their selective inhibitions against butyrylcholinesterase and monoamine oxidase-B.
3/2022Conjugated Dienones from Differently Substituted Cinnamaldehyde as Highly Potent Monoamine Oxidase-B Inhibitors: Synthesis, Biochemistry, and Computational Chemistry.
11/2021Replacement of Chalcone-Ethers with Chalcone-Thioethers as Potent and Highly Selective Monoamine Oxidase-B Inhibitors and Their Protein-Ligand Interactions.
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Jong Min Oh Research Topics

Disease

8Neurodegenerative Diseases (Neurodegenerative Disease)
01/2024 - 11/2020
7Parkinson Disease (Parkinson's Disease)
01/2024 - 08/2021
6Alzheimer Disease (Alzheimer's Disease)
01/2024 - 11/2020
4Nervous System Diseases (Neurological Disorders)
11/2021 - 05/2018
3Neuroblastoma
01/2024 - 08/2023
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2024
1Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
12/2023
1Dementia (Dementias)
09/2022
1Infections
11/2018

Drug/Important Bio-Agent (IBA)

18Monoamine Oxidase (MAO)IBA
01/2024 - 05/2018
3Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA
01/2024 - 09/2022
3EnzymesIBA
12/2023 - 05/2018
2RotenoneIBA
11/2023 - 08/2023
2Cholinesterases (Cholinesterase)IBA
09/2022 - 08/2021
2ChalconesIBA
08/2021 - 06/2021
1Neuroprotective AgentsIBA
01/2024
1IsatinIBA
01/2024
1LipopolysaccharidesIBA
01/2024
1AzolesIBA
12/2023
1Linezolid (Zyvox)FDA Link
12/2023
1OximesIBA
08/2023
1Proteins (Proteins, Gene)FDA Link
08/2021
1Amyloid (Amyloid Fibrils)IBA
08/2021
1Oxidoreductases (Dehydrogenase)IBA
08/2021
1PiperazineIBA
08/2021
12-(N-cyclohexylamino)ethanesulfonic acid (CHES)IBA
08/2021
1Anti-Infective Agents (Microbicides)IBA
11/2018
1divaricatic acidIBA
11/2018
1GlycosidesIBA
05/2018
1tilianinIBA
05/2018
1flavoneIBA
05/2018
1acacetinIBA
05/2018

Therapy/Procedure

2Therapeutics
07/2021 - 01/2021