Alison O'Mahony Selected Research

RN486

4/2012

RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents.

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Alison O'Mahony Research Topics

Disease

4	Inflammation (Inflammations) 01/2023 - 04/2012
3	Rheumatoid Arthritis 01/2019 - 04/2012
3	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 01/2013
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 08/2022 - 12/2015
2	Hypersensitivity (Allergy) 07/2017 - 04/2012
2	Neoplasms (Cancer) 12/2015 - 04/2014
1	Skin Diseases (Skin Disease) 01/2024
1	Body Weight (Weight, Body) 01/2023
1	Frailty 01/2023
1	Primary Myelofibrosis (Myelosclerosis) 01/2019
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2019
1	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2018
1	Leukemia 12/2015
1	Genetic Translocation (Chromosomal Translocation) 12/2015
1	Ankylosing Spondylitis 08/2015
1	Psoriatic Arthritis 08/2015
1	Thrombosis (Thrombus) 01/2015
1	Hypoxia (Hypoxemia) 01/2015
1	Immune Complex Diseases (Immune Complex Disease) 04/2012
1	Experimental Arthritis 04/2012
1	Arthritis (Polyarthritis) 04/2012
1	Seizures (Absence Seizure) 10/2006
1	AIDS-Related Complex (ARC) 10/2006

Drug/Important Bio-Agent (IBA)

2	Agammaglobulinaemia Tyrosine KinaseIBA 01/2019 - 04/2012
2	Methotrexate (Mexate)FDA LinkGeneric 01/2018 - 04/2012
2	Interleukin-17 (Interleukin 17)IBA 08/2015 - 01/2013
1	isomyosmineIBA 01/2023
1	TubulinIBA 08/2022
1	11- (2- pyrrolidin- 1- ylethoxy)- 14,19- dioxa- 5,7,26- triazatetracyclo(19.3.1.1(2,6).1(8,12))heptacosa- 1(25),2(26),3,5,8,10,12(27),16,21,23- decaeneIBA 01/2019
1	fedratinibIBA 01/2019
1	Fc Receptors (Fc Receptor)IBA 01/2019
1	N- (cyanomethyl)- 4- (2- ((4- (4- morpholinyl)phenyl)amino)- 4- pyrimidinyl)benzamideIBA 01/2019
1	ruxolitinibIBA 01/2019
1	evobrutinibIBA 01/2019
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2018
1	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 07/2017
1	I-CBP112IBA 12/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2015
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 12/2015
1	Monoclonal AntibodiesIBA 08/2015
1	Interleukin-23 (Interleukin 23)IBA 08/2015
1	LipidsIBA 01/2015
1	Thromboplastin (Tissue Factor)IBA 01/2015
1	Phosphotransferases (Kinase)IBA 04/2014
1	AntibodiesIBA 01/2013
1	CytokinesIBA 01/2013
1	Phosphatidylinositols (Phosphatidylinositol)IBA 04/2012
1	RN486IBA 04/2012
1	NF-KappaB Inhibitor alphaIBA 10/2006
1	Proteins (Proteins, Gene)FDA Link 10/2006

Therapy/Procedure

2	Therapeutics 12/2015 - 04/2014
1	Topical Administration 01/2024
1	Cell Transplantation 01/2018