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Stephen J Nicholls Selected Research

Atorvastatin (Lipitor)

1/2022Pharmacological Inhibition of CETP (Cholesteryl Ester Transfer Protein) Increases HDL (High-Density Lipoprotein) That Contains ApoC3 and Other HDL Subspecies Associated With Higher Risk of Coronary Heart Disease.
1/2021Combination of bempedoic acid, ezetimibe, and atorvastatin in patients with hypercholesterolemia: A randomized clinical trial.
11/2019Effect of selective BET protein inhibitor apabetalone on cardiovascular outcomes in patients with acute coronary syndrome and diabetes: Rationale, design, and baseline characteristics of the BETonMACE trial.
1/2019Association of Initial and Serial C-Reactive Protein Levels With Adverse Cardiovascular Events and Death After Acute Coronary Syndrome: A Secondary Analysis of the VISTA-16 Trial.
1/2018Modeling Statin-Induced Reductions of Cardiovascular Events in Primary Prevention: A VOYAGER Meta-Analysis.
8/2017Lipoprotein(a) and coronary atheroma progression rates during long-term high-intensity statin therapy: Insights from SATURN.
1/2017Comparative effects of cholesteryl ester transfer protein inhibition, statin or ezetimibe on lipid factors: The ACCENTUATE trial.
11/2016Coronary atheroma progression rates in men and women following high-intensity statin therapy: A pooled analysis of REVERSAL, ASTEROID and SATURN.
8/2015Statin-induced coronary artery disease regression rates differ in men and women.
11/2014Antiatherosclerotic effects of long-term maximally intensive statin therapy after acute coronary syndrome: insights from Study of Coronary Atheroma by Intravascular Ultrasound: Effect of Rosuvastatin Versus Atorvastatin.
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Stephen J Nicholls Research Topics

Disease

107Coronary Artery Disease (Coronary Atherosclerosis)
06/2024 - 10/2004
105Atherosclerotic Plaque (Atheroma)
06/2024 - 08/2005
85Cardiovascular Diseases (Cardiovascular Disease)
06/2024 - 01/2005
75Atherosclerosis
02/2024 - 10/2004
54Myocardial Infarction
04/2024 - 07/2007
36Inflammation (Inflammations)
03/2024 - 06/2005
36Acute Coronary Syndrome
11/2023 - 01/2008
32Stroke (Strokes)
04/2024 - 09/2007
29Type 2 Diabetes Mellitus (MODY)
06/2024 - 09/2007
28Coronary Disease (Coronary Heart Disease)
11/2023 - 04/2006
21Disease Progression
02/2021 - 04/2006
18Heart Failure
06/2023 - 09/2007
17Dyslipidemias (Dyslipidemia)
07/2023 - 03/2007
15Hypertension (High Blood Pressure)
11/2023 - 06/2006
15Unstable Angina
10/2022 - 11/2012
14Thrombosis (Thrombus)
03/2024 - 08/2006
14Vascular Diseases (Vascular Disease)
10/2022 - 09/2007
10ST Elevation Myocardial Infarction
01/2022 - 08/2013
10Diabetes Mellitus
01/2021 - 01/2010
9Hypertriglyceridemia
12/2020 - 05/2010
8Pathologic Constriction (Stenosis)
02/2024 - 11/2006
8AIDS-Related Complex (ARC)
01/2023 - 08/2014
7Ischemia
12/2022 - 03/2014
7Hemorrhage
10/2022 - 01/2018
6Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2024 - 04/2008
5Hypoxia (Hypoxemia)
03/2024 - 01/2018
5Obesity
02/2024 - 06/2006
5Hypercholesterolemia
01/2024 - 03/2007
5Neoplasms (Cancer)
12/2023 - 01/2019
5Hyperlipidemias (Hyperlipidemia)
11/2023 - 11/2011
4Hyperlipoproteinemia Type II (Familial Hypercholesterolemia)
05/2024 - 01/2017
4Body Weight (Weight, Body)
02/2024 - 04/2008
4Cholelithiasis
01/2024 - 04/2023
4Gout
01/2024 - 04/2023
4Genetic Risk Score
10/2023 - 10/2019
4Chronic Renal Insufficiency
01/2023 - 05/2013
4Rupture
01/2022 - 08/2013
3Aortic Valve Stenosis (Aortic Stenosis)
04/2024 - 01/2023
3Ischemic Stroke
02/2024 - 11/2012
3Heart Diseases (Heart Disease)
01/2022 - 01/2019

Drug/Important Bio-Agent (IBA)

79Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2024 - 11/2005
67LipidsIBA
05/2024 - 12/2005
53LDL CholesterolIBA
05/2024 - 02/2007
40oxidized low density lipoproteinIBA
05/2024 - 01/2006
39HDL CholesterolIBA
07/2023 - 02/2007
27CholesterolIBA
04/2024 - 06/2005
26Lipoproteins (Lipoprotein)IBA
05/2024 - 02/2007
26HDL LipoproteinsIBA
04/2024 - 08/2005
26Atorvastatin (Lipitor)FDA Link
01/2022 - 11/2005
25Triglycerides (Triacylglycerol)IBA
04/2024 - 03/2007
24omega-Chloroacetophenone (Mace)IBA
02/2024 - 05/2010
24C-Reactive ProteinIBA
01/2024 - 06/2006
22Rosuvastatin Calcium (Crestor)FDA Link
11/2019 - 04/2006
17Cholesterol Ester Transfer ProteinsIBA
07/2023 - 06/2005
14Lipoprotein(a)IBA
04/2024 - 08/2017
14CalciumIBA
10/2023 - 01/2007
14evacetrapibIBA
10/2022 - 11/2011
13Apolipoprotein A-I (Apolipoprotein A1)IBA
04/2024 - 02/2007
13Biomarkers (Surrogate Marker)IBA
01/2023 - 01/2008
12Proteins (Proteins, Gene)FDA Link
04/2024 - 10/2007
12evolocumabIBA
01/2023 - 06/2016
12apabetaloneIBA
09/2022 - 03/2011
12LDL Lipoproteins (beta Lipoproteins)IBA
01/2022 - 05/2007
9Glucose (Dextrose)FDA LinkGeneric
10/2023 - 04/2012
9ApolipoproteinsIBA
07/2023 - 02/2007
9Peroxidase (Myeloperoxidase)IBA
02/2014 - 10/2004
88- hydroxy- 2,2,14,14- tetramethylpentadecanedioic acidIBA
01/2024 - 01/2021
7PCSK9 InhibitorsIBA
11/2023 - 06/2016
5CreatinineIBA
01/2024 - 03/2007
5Immune Checkpoint InhibitorsIBA
12/2023 - 12/2022
5Proprotein Convertase 9IBA
11/2023 - 12/2016
5Ezetimibe (Zetia)FDA Link
01/2023 - 09/2013
5empagliflozinIBA
12/2022 - 10/2020
5Insulin (Novolin)FDA Link
02/2022 - 04/2008
5Phenobarbital (Luminal)FDA Link
01/2020 - 03/2006
5aleglitazarIBA
01/2020 - 09/2013
4EnzymesIBA
11/2023 - 07/2006
4TicagrelorIBA
01/2022 - 01/2018
4Clopidogrel (Plavix)FDA Link
01/2022 - 01/2018
4Apolipoproteins B (ApoB)IBA
12/2020 - 01/2016
4Peroxisome Proliferator-Activated Receptors (PPAR)IBA
01/2020 - 09/2013
4Albuterol (Salbutamol)FDA LinkGeneric
01/2018 - 11/2014
4Pioglitazone (Actos)FDA Link
07/2015 - 09/2007
4Oxidants (Oxidizing Agents)IBA
03/2010 - 10/2004
3CSL112IBA
04/2024 - 01/2021
3Messenger RNA (mRNA)IBA
03/2024 - 01/2021
3tirzepatideIBA
02/2024 - 01/2022
3Apolipoproteins E (ApoE)IBA
01/2023 - 01/2021
3Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
10/2022 - 11/2018
3torcetrapibIBA
01/2022 - 03/2007

Therapy/Procedure

116Therapeutics
05/2024 - 06/2005
8Secondary Prevention
12/2023 - 08/2019
8Percutaneous Coronary Intervention
10/2022 - 07/2012
7Stents
03/2024 - 01/2018
6Glycemic Control
02/2024 - 09/2007
6Transcatheter Aortic Valve Replacement
01/2023 - 08/2016
4Drug-Eluting Stents
10/2022 - 07/2012
4Thrombolytic Therapy
01/2022 - 01/2018
3Cardiac Rehabilitation
02/2022 - 04/2019
3Drug Therapy (Chemotherapy)
01/2021 - 06/2014