Merrilee Needham Selected Research

Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)

11/2016	Treatment and outcomes in necrotising autoimmune myopathy: An Australian perspective.
11/2011	Necrotizing autoimmune myopathy.
2/2007	Progressive myopathy with up-regulation of MHC-I associated with statin therapy.

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Merrilee Needham Research Topics

Disease

13	Inclusion Body Myositis 12/2023 - 07/2007
9	Muscular Diseases (Myopathy) 10/2023 - 02/2007
8	Myositis (Idiopathic Inflammatory Myopathies) 04/2024 - 07/2007
3	Muscle Weakness 10/2023 - 07/2007
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2023 - 01/2021
2	Motor Neuron Disease (Primary Lateral Sclerosis) 02/2024 - 06/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2021 - 11/2016
2	Disease Susceptibility (Diathesis) 09/2012 - 11/2009
1	Weight Loss (Weight Reduction) 02/2024
1	Dermatomyositis (Dermatopolymyositis) 05/2023
1	Disease Progression 01/2023
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2023
1	Proteostasis Deficiencies 01/2023
1	Bone Diseases (Bone Disease) 01/2023
1	Diarrhea 01/2021
1	Exanthema (Rash) 01/2021
1	Fatigue 01/2021
1	Nausea 01/2021
1	Infarction (Infarctions) 12/2020
1	Spinal Injuries (Spinal Injury) 12/2020
1	Cerebrospinal Fluid Leak 12/2020
1	Adenocarcinoma of Lung 01/2019
1	Myocardial Infarction 01/2019
1	Spasm (Spasms) 01/2019
1	Hemorrhage 01/2019
1	Encephalitis (Encephalitis, Rasmussen) 06/2018
1	Anti-N-Methyl-D-Aspartate Receptor Encephalitis 06/2018
1	Connective Tissue Diseases (Connective Tissue Disease) 11/2016
1	Neoplasms (Cancer) 11/2016
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 12/2015
1	Muscular Dystrophies (Muscular Dystrophy) 12/2015
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2013
1	Progeria (Hutchinson Gilford Syndrome) 01/2013
1	Multiple Sclerosis 01/2013
1	Atrophy 07/2007

Drug/Important Bio-Agent (IBA)

4	Biomarkers (Surrogate Marker)IBA 11/2023 - 11/2013
4	Creatine Kinase (Creatine Phosphokinase)IBA 10/2023 - 11/2011
3	AntibodiesIBA 12/2023 - 11/2016
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 11/2016 - 02/2007
3	Proteins (Proteins, Gene)FDA Link 03/2016 - 01/2013
2	Oxidoreductases (Dehydrogenase)IBA 10/2023 - 11/2016
2	Testosterone (Sustanon)FDA Link 01/2023 - 01/2022
2	Valosin Containing ProteinIBA 01/2023 - 11/2016
2	bimagrumabIBA 01/2021 - 01/2019
2	SteroidsIBA 11/2016 - 01/2016
2	HLA-DRB1*03:01 antigenIBA 09/2012 - 06/2011
2	HLA-DRB1 Chains (HLA DRB1)IBA 09/2012 - 11/2009
1	Riluzole FDA LinkGeneric 02/2024
1	5'-Nucleotidase (5' Nucleotidase)IBA 12/2023
1	Coenzyme A (CoA)IBA 10/2023
1	COVID-19 VaccinesIBA 01/2023
1	reldesemtivIBA 01/2021
1	Pentoxifylline (Trental)FDA LinkGeneric 12/2020
1	Oxygen (Dioxygen)IBA 12/2020
1	Antidepressive Agents (Antidepressants)IBA 01/2019
1	Hypnotics and Sedatives (Sedatives)IBA 01/2019
1	Monoclonal AntibodiesIBA 01/2019
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 06/2018
1	3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)IBA 11/2016
1	Signal Recognition ParticleIBA 11/2016
1	GlucocorticoidsIBA 01/2016
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2016
1	CollagenIBA 12/2015
1	Pyruvic Acid (Pyruvate)IBA 11/2013
1	fibroblast growth factor 21IBA 11/2013
1	Lactic Acid (Lactate)FDA LinkGeneric 11/2013
1	HLA-DRB3 Chains (HLA DRB3)IBA 01/2013
1	InterferonsIBA 01/2013
1	Interferon beta-1a FDA Link 01/2013
1	Lamin Type A (Lamin A)IBA 01/2013
1	HLA-B Antigens (HLA-B)IBA 06/2011
1	ApolipoproteinsIBA 02/2008
1	Apolipoproteins E (ApoE)IBA 02/2008

Therapy/Procedure

5	Therapeutics 12/2021 - 02/2007
3	Immunotherapy 11/2016 - 07/2007
1	Self-Help Devices (Assistive Technology) 04/2024
1	Enteral Nutrition (Feeding, Tube) 02/2024
1	Gastrostomy 02/2024
1	Noninvasive Ventilation 02/2024
1	Contraindications 01/2019