Akinobu Nakamura Selected Research

Atherosclerotic Plaque (Atheroma)

2/2023	Lipid Droplet Protein PLIN1 Regulates Inflammatory Polarity in Human Macrophages and is Involved in Atherosclerotic Plaque Development by Promoting Stable Lipid Storage.
8/2018	The data of change in macrophage gene expression which induced by perilipin 1 overexpression.
1/2018	Overexpression of perilipin1 protects against atheroma progression in apolipoprotein E knockout mice.

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Akinobu Nakamura Research Topics

Disease

55	Type 2 Diabetes Mellitus (MODY) 05/2024 - 01/2009
15	Body Weight (Weight, Body) 04/2024 - 03/2009
13	Insulin Resistance 05/2024 - 01/2007
12	Hypoglycemia (Reactive Hypoglycemia) 05/2022 - 01/2016
9	Fatty Liver 05/2024 - 05/2011
8	Hyperglycemia 12/2023 - 05/2014
6	Hypertension (High Blood Pressure) 10/2021 - 01/2015
5	Hypertriglyceridemia 02/2024 - 09/2020
5	Neoplasms (Cancer) 12/2023 - 01/2016
5	Adenoma (Adenomas) 10/2023 - 11/2018
5	Non-alcoholic Fatty Liver Disease 08/2023 - 11/2011
5	Atherosclerosis 02/2023 - 10/2017
5	Pituitary Neoplasms (Pituitary Adenoma) 07/2021 - 01/2019
5	Insulinoma 09/2018 - 08/2006
4	Chronic Renal Insufficiency 02/2024 - 11/2019
4	Glucose Intolerance 10/2021 - 03/2017
4	Diabetes Mellitus 08/2021 - 03/2017
4	Dyslipidemias (Dyslipidemia) 02/2021 - 11/2017
3	Ketosis 12/2023 - 09/2019
3	Disease Progression 12/2023 - 01/2019
3	Adrenal Insufficiency (Adrenal Gland Hypofunction) 12/2023 - 07/2014
3	Atherosclerotic Plaque (Atheroma) 02/2023 - 01/2018
3	Obesity 02/2021 - 12/2019
3	Hyperinsulinism (Hyperinsulinemia) 07/2020 - 11/2013
3	Albuminuria 01/2020 - 01/2015
3	Gitelman Syndrome 07/2019 - 01/2006
2	Renal Cell Carcinoma (Grawitz Tumor) 12/2023 - 10/2019
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/2022 - 01/2016
2	Hypophosphatemia 11/2021 - 09/2017
2	Weight Loss (Weight Reduction) 07/2021 - 07/2014
2	Infections 04/2021 - 01/2021
2	Fever (Fevers) 04/2021 - 01/2019
2	Acromegaly 01/2021 - 01/2019
2	Hyperaldosteronism (Conn Syndrome) 06/2020 - 11/2018
2	Hyponatremia 10/2019 - 01/2017
2	Hypocalcemia 07/2019 - 09/2017
2	Alkalosis 07/2019 - 07/2008
2	Edema (Dropsy) 01/2016 - 10/2010

Drug/Important Bio-Agent (IBA)

42	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 05/2011
20	Insulin (Novolin)FDA Link 12/2023 - 01/2009
9	LipidsIBA 12/2023 - 03/2009
8	SodiumIBA 05/2022 - 10/2010
8	Dipeptidyl-Peptidase IV InhibitorsIBA 01/2022 - 01/2017
8	Blood Glucose (Blood Sugar)IBA 01/2022 - 03/2015
7	semaglutideIBA 05/2024 - 03/2021
6	GlucokinaseIBA 05/2022 - 01/2007
6	Hypoglycemic Agents (Hypoglycemics)IBA 05/2022 - 08/2006
5	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 04/2024 - 01/2018
5	Adrenocorticotropic Hormone (ACTH)FDA Link 12/2023 - 10/2019
5	Hydrocortisone (Cortisol)FDA LinkGeneric 12/2023 - 10/2019
5	Liraglutide FDA Link 01/2023 - 07/2015
5	Triglycerides (Triacylglycerol)IBA 07/2021 - 03/2009
5	ipragliflozinIBA 11/2019 - 06/2016
4	Metformin (Glucophage)FDA LinkGeneric 05/2024 - 10/2017
4	(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA 02/2024 - 10/2022
4	ProinsulinIBA 02/2024 - 01/2020
4	NivolumabIBA 12/2023 - 01/2017
4	Sodium-Glucose Transport ProteinsIBA 05/2022 - 01/2020
4	VildagliptinIBA 10/2017 - 01/2013
4	Insulin Receptor Substrate ProteinsIBA 05/2014 - 03/2009
3	C-PeptideIBA 02/2024 - 01/2018
3	Hormones (Hormone)IBA 10/2023 - 04/2017
3	Semaphorins (Semaphorin)IBA 08/2023 - 03/2021
3	Glucagon-Like Peptide-1 Receptor AgonistsIBA 08/2023 - 05/2019
3	Proteins (Proteins, Gene)FDA Link 02/2023 - 12/2020
3	dulaglutideIBA 01/2023 - 05/2019
3	AlbuminsIBA 01/2022 - 03/2019
3	dapagliflozinIBA 07/2021 - 01/2017
3	Pioglitazone (Actos)FDA Link 07/2021 - 10/2010
3	Hemoglobins (Hemoglobin)IBA 05/2021 - 01/2017
3	oxidized low density lipoproteinIBA 01/2021 - 01/2018
3	PotassiumIBA 07/2019 - 01/2006
3	MagnesiumIBA 09/2017 - 01/2006
3	Sitagliptin Phosphate (Januvia)FDA Link 04/2017 - 07/2015
2	imegliminIBA 05/2024 - 11/2022
2	Fibric Acids (Fibrates)IBA 02/2024 - 10/2022
2	Immune Checkpoint InhibitorsIBA 12/2023 - 10/2019
2	Messenger RNA (mRNA)IBA 10/2023 - 01/2021
2	AdiponectinIBA 01/2023 - 09/2018
2	IncretinsIBA 01/2022 - 01/2022
2	insulin degludecIBA 01/2022 - 01/2016
2	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2018
2	Phosphates (Orthophosphate)IBA 11/2021 - 09/2017
2	Fibroblast Growth Factor-23IBA 11/2021 - 09/2017
2	1,5- anhydro- 1- (5- (4- ethoxybenzyl)- 2- methoxy- 4- methylphenyl)- 1- thioglucitolIBA 10/2021 - 01/2020
2	CanagliflozinIBA 08/2021 - 01/2020
2	3- (4- (4- (3- methyl- 1- phenyl- 1H- pyrazol- 5- yl)piperazin- 1- yl)pyrrolidin- 2- ylcarbonyl)thiazolidineIBA 08/2021 - 01/2020
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 07/2021 - 01/2019
2	Antiviral Agents (Antivirals)IBA 04/2021 - 01/2018
2	Glucagon-Like Peptide-1 ReceptorIBA 03/2021 - 05/2019
2	CholesterolIBA 01/2021 - 05/2011
2	AldosteroneIBA 06/2020 - 11/2018
2	Sodium-Glucose Transporter 2 InhibitorsIBA 01/2020 - 01/2017
2	Octreotide (Sandostatin)FDA LinkGeneric 01/2019 - 01/2016
2	ApolipoproteinsIBA 08/2018 - 01/2018
2	SymportersIBA 01/2017 - 06/2016
2	voglibose (Basen)IBA 09/2014 - 02/2014

Therapy/Procedure

21	Therapeutics 12/2023 - 01/2009
16	Glycemic Control 04/2024 - 01/2015
2	Injections 12/2019 - 01/2009